Zobrazeno 1 - 10
of 259
pro vyhledávání: '"Patrick W. Mantyh"'
Autor:
Lisa A. Majuta, Jean-Marc G. Guedon, Stefanie A.T. Mitchell, Michael A. Kuskowski, Patrick W. Mantyh
Publikováno v:
PAIN Reports, Vol 2, Iss 5, p e614 (2017)
Abstract. Introduction:. Cancer-induced bone pain (CIBP) is the most common type of pain with cancer. In humans, this pain can be difficult to control and highly disabling. A major problem with CIBP in humans is that it increases on weight-bearing an
Externí odkaz:
https://doaj.org/article/72b6241c34274ad09fc0d44f6a85393e
Autor:
Patrick W. Mantyh, Geraldine Longo, Stephane Chartier, Michelle N. Fealk, Lisa Majuta, Michelle L. Thompson, Gwen McCaffrey
This film depicts the spontaneous nocifensive behavior of a mouse at Day 17 post-cancer cell injection. Throughout the film there are several visual cues that are indicative of nocifensive behavior. The pronounced changes in behavior and movements of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd9dc3033d5eb7310609014f602e5e8
https://doi.org/10.1158/0008-5472.22403099.v1
https://doi.org/10.1158/0008-5472.22403099.v1
Autor:
Patrick W. Mantyh, Geraldine Longo, Stephane Chartier, Michelle N. Fealk, Lisa Majuta, Michelle L. Thompson, Gwen McCaffrey
This film depicts the nocifensive behavior of a naïve mouse. During the film, when the mouse is stationary, the toes of the left foot are spread out and a range of brightness appears on the bottom of the foot because it is bearing weight on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c95f5facc642f34099e63bd6a8dd7d9
https://doi.org/10.1158/0008-5472.22403105.v1
https://doi.org/10.1158/0008-5472.22403105.v1
Autor:
Patrick W. Mantyh, Geraldine Longo, Stephane Chartier, Michelle N. Fealk, Lisa Majuta, Michelle L. Thompson, Gwen McCaffrey
This file provides supplemental materials and methods, supplemental video legends, and supplemental material references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6670b67cad6fd76d02f057f994787843
https://doi.org/10.1158/0008-5472.22403114
https://doi.org/10.1158/0008-5472.22403114
Autor:
Patrick W. Mantyh, Geraldine Longo, Stephane Chartier, Michelle N. Fealk, Lisa Majuta, Michelle L. Thompson, Gwen McCaffrey
Supplementary Figure 1. Patella displacement is a confounding factor in bone cancer pain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4339e2b70ef841ed739b538881d15cde
https://doi.org/10.1158/0008-5472.22403111.v1
https://doi.org/10.1158/0008-5472.22403111.v1
Publikováno v:
Journal of Pain Research. 13:1223-1241
Nerve growth factor (NGF) is a neurotrophic protein essential for the growth, differentiation, and survival of sympathetic and sensory afferent neurons during development. A substantial body of evidence, based on both animal and human studies, demons
Autor:
Tony L. Yaksh, Sean D. Donevan, Patrick W. Mantyh, Lars Viktrup, Mojgan Sadrarhami, Yvonne D'Arcy, J. Hall
Publikováno v:
Postgraduate medicine. 133(8)
Osteoarthritis (OA) is a common difficult-to-treat condition where the goal, in the absence of disease-modifying treatments, is to alleviate symptoms such as pain and loss of function. Acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), and
Autor:
Patrick W. Mantyh
Publikováno v:
Br J Clin Pharmacol
Disorders of the skeleton are frequently accompanied by bone pain and a decline in the functional status of the patient. Bone pain occurs following a variety of injuries and diseases including bone fracture, osteoarthritis, low back pain, orthopedic
Autor:
Ashish Bhandari, Patrick W. Mantyh, Edgar L. Ross, Jason D. Ross, Tony L. Yaksh, Roshni Ramachandran
Publikováno v:
Future Drug Discovery. 2
Opioids have long been the mainstay of cancer pain treatment and have been used without any consideration for their effect on cancer growth and long-term prognosis. There is now growing evidence that the continued use of opioids for this indication s
Publikováno v:
Neuroscience. 387:178-190
Although bone is continually being remodeled and ultimately declines with aging, little is known whether similar changes occur in the sensory and sympathetic nerve fibers that innervate bone. Here, immunohistochemistry and confocal microscopy were us