Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Patrick W. Keeley"'
Autor:
Bridget Kulesh, Rachel Bozadjian, Ryan J. Parisi, Stephanie A. Leong, Amanda G. Kautzman, Benjamin E. Reese, Patrick W. Keeley
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Sequence variants modulating gene function or expression affect various heritable traits, including the number of neurons within a population. The present study employed a forward-genetic approach to identify candidate causal genes and their sequence
Externí odkaz:
https://doaj.org/article/87bdd516047d4affb725e0d70ea2bd8a
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Multiple factors regulate the differentiation of neuronal morphology during development, including interactions with afferents, targets, and homotypic neighbors, as well as cell-intrinsic transcriptional regulation. Retinal bipolar cells provide an e
Externí odkaz:
https://doaj.org/article/01d28de2ff8f413988cdc284da4307e5
Autor:
Amanda G. Kautzman, Patrick W. Keeley, Caroline R. Ackley, Stephanie Leong, Irene E. Whitney, Benjamin E. Reese
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The present study interrogated a quantitative trait locus (QTL) on Chr 4 associated with the population sizes of two types of bipolar cell in the mouse retina. This locus was identified by quantifying the number of rod bipolar cells and Type 2 cone b
Externí odkaz:
https://doaj.org/article/ae0ed00fe46a4202a17bd37f98a71eb8
Autor:
Amanda G. Kautzman, Patrick W. Keeley, Sarra Borhanian, Caroline R. Ackley, Benjamin E. Reese
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Genetic variants modulate the numbers of various retinal cell types in mice. For instance, there is minimal variation in the number of rod bipolar cells (RBCs) in two inbred strains of mice (A/J and C57BL/6J), yet their F1 offspring contain significa
Externí odkaz:
https://doaj.org/article/f48ddf9532314d76af50c7d632d216a2
Autor:
Patrick W. Keeley, Benjamin E. Reese
Publikováno v:
Frontiers in Neuroanatomy, Vol 8 (2014)
Retinal neurons are often arranged as non-random distributions called mosaics, as their somata minimize proximity to neighboring cells of the same type. The horizontal cells serve as an example of such a mosaic, but little is known about the developm
Externí odkaz:
https://doaj.org/article/4bb8a41dda774a73b3f4564928083e00
Publikováno v:
Development (Cambridge, England).
The population sizes of different retinal cell types vary between different strains of mice, and that variation can be mapped to genomic loci in order to identify its polygenic origin. In some cases, controlling genes act independently, whereas in ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabfd8684a58e7beb40864dda6f9bd7b
https://pubmed.ncbi.nlm.nih.gov/36537573
https://pubmed.ncbi.nlm.nih.gov/36537573
Publikováno v:
Journal of anatomyREFERENCES.
The precise specification of cellular fate is thought to ensure the production of the correct number of neurons within a population. Programmed cell death may be an additional mechanism controlling cell number, believed to refine the proper ratio of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5652f80c4dc7ebf36cd5d0f15f7bb113
https://pubmed.ncbi.nlm.nih.gov/35292986
https://pubmed.ncbi.nlm.nih.gov/35292986
Autor:
Peter J. Coffey, Alexander Smolentsev, Madison D. Lockwood, Patrick W. Keeley, Ryan Sadjadi, James A. Thomson, Barbara A Blodi, Dennis O. Clegg, Benjamin E. Reese, Huishi Toh, Rachel V. Bozadjian
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology, vol 99, iss 10
Laboratory investigation; a journal of technical methods and pathology
Laboratory investigation; a journal of technical methods and pathology
Diabetic retinopathy is the most common microvascular complication of diabetes and is a major cause of blindness, but an understanding of the pathogenesis of the disease has been hampered by a lack of accurate animal models. Here, we explore the dyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c26cad1e597cb66d15d25520dc3e97
https://doi.org/10.1038/s41374-019-0264-3
https://doi.org/10.1038/s41374-019-0264-3
Autor:
Benjamin E. Reese, Ace J. St. John, Patrick W. Keeley, Jordan D. Vieler, Jason J Kim, Mikayla C. Lebo
Publikováno v:
J Neurosci
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 1
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 1
Amacrine cells of the retina are conspicuously variable in their morphologies, their population demographics, and their ensuing functions. Vesicular glutamate transporter 3 (VGluT3) amacrine cells are a recently characterized type of amacrine cell ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c157f4c039270f639a1ed4bb253a4698
https://pubmed.ncbi.nlm.nih.gov/33208470
https://pubmed.ncbi.nlm.nih.gov/33208470
