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pro vyhledávání: '"Patrick W. Adams"'
Publikováno v:
Human Immunology. 80:65-66
Publikováno v:
Human Immunology. 80:173
Autor:
Aisha A. Eltayeb, Joseph Williamson, Audrey Ai Chin Lee, Nathan Johnson, Hemant K. Parekh, Paula L. Steller, Patrick W. Adams
Publikováno v:
Human Immunology. 79:151
Aim To systematically assess the effectiveness of EDTA in unmasking clinically relevant HLA alloantibodies Methods Serum samples from transplant (txp) patients collected for clinical testing were pre-treated with various concentrations of EDTA for 15
Autor:
Gregg A. Hadley, Ronald P. Pelletier, Patrick W. Adams, Ronald M. Ferguson, Mitchell L. Henry, Zhangsheng Yu
Publikováno v:
Ibnosina Journal of Medicine and Biomedical Sciences. :7-15
Background: Chronic renal allograft loss is considered as immunologically mediated when donor-specific alloantibodies are detected. However, remotely detected alloantibodies with lack of detection more proximate to graft loss occurrence may obscure t
Publikováno v:
American Journal of Transplantation. 2:926-933
Evidence of transplant recipient cellular sensitization towards donor antigens has rarely been directly measured. Rather, sensitization has been generally inferred by the presence of detectable allo-reactive or donor-reactive antibodies. In this stud
Autor:
Charles G. Orosz, Ronald P. Pelletier, Patrice Hennessey, Alice A. Bickerstaff, Patrick W. Adams
Publikováno v:
Transplant Immunology. 9:143-147
Based on discrepancies between various laboratory and clinical observations, skepticism has developed regarding the pre-clinical value of rodent immunologic studies. In this article, we review the progression of our murine and human studies over the
Autor:
Patrick W. Adams, Hemant K. Parekh, Joseph Williamson, Aisha Eltayeb, Paula Steller, Nebila Abdulwahab, Todd Hertel, Adam Schoen
Publikováno v:
Human Immunology. 78:229
Solid phase assays (SPAs) have significantly improved our ability to assess the presence of anti-HLA antibody (Abs) that would be deleterious to the allograft post-transplant. SPAs have also demonstrated increased specificity and sensitivity for allo
Publikováno v:
Human Immunology. 60:855-861
The complement-dependent lymphocytotoxicity crossmatch (CXM) is the presently accepted standard for detection of donor-reactive alloantibodies in transplant patients. However, the newer flow cytometric (FXM) and ELISA (EXM) crossmatch technologies ar
Publikováno v:
Transplantation. 66:67-77
Background Cytomegalovirus (CMV) has been implicated as an exacerbating agent in the development of transplant vascular sclerosis; however, specific etiologic mechanisms remain unresolved. Based upon our previous observations that CMV-infected endoth
Autor:
Patrick W. Adams, Ronald P. Pelletier, Elmahdi A. Elkhammas, Ronald M. Ferguson, Ginny L. Bumgardner, Elizabeth A. Davies, Mitchell L. Henry, Charles G. Orosz
Publikováno v:
Transplantation. 63:1639-1645
We retrospectively compared the clinical and financial impact of a final cross-match by T cell flow cytometry (FXM) versus conventional complement-dependent cytotoxicity (CXM) in consecutive primary cadaveric kidney (K) and primary simultaneous cadav