Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Patrick W Marsh"'
Autor:
Robert Verity, Ozkan Aydemir, Nicholas F. Brazeau, Oliver J. Watson, Nicholas J. Hathaway, Melchior Kashamuka Mwandagalirwa, Patrick W. Marsh, Kyaw Thwai, Travis Fulton, Madeline Denton, Andrew P. Morgan, Jonathan B. Parr, Patrick K. Tumwebaze, Melissa Conrad, Philip J. Rosenthal, Deus S. Ishengoma, Jeremiah Ngondi, Julie Gutman, Modest Mulenga, Douglas E. Norris, William J. Moss, Benedicta A. Mensah, James L. Myers-Hansen, Anita Ghansah, Antoinette K. Tshefu, Azra C. Ghani, Steven R. Meshnick, Jeffrey A. Bailey, Jonathan J. Juliano
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The genome of the malaria parasite Plasmodium falciparum contains a record of past evolutionary forces. Here, using 2537 parasite sequences from the Democratic Republic of the Congo, the authors demonstrate how drug pressure and human movement have s
Externí odkaz:
https://doaj.org/article/66be251847414c22986caeb0cfc8324e
Autor:
Ozkan Aydemir, Benedicta Mensah, Patrick W. Marsh, Benjamin Abuaku, James Leslie Myers-Hansen, Jeffrey A. Bailey, Anita Ghansah
Publikováno v:
PeerJ, Vol 9, p e11794 (2021)
Antimalarial resistance surveillance in sub-Saharan Africa is often constrained by logistical and financial challenges limiting its breadth and frequency. At two sites in Ghana, we have piloted a streamlined sample pooling process created immediately
Externí odkaz:
https://doaj.org/article/e20a1fa2d4284d5fa75b4791c9fbc788
Autor:
Gaurav Chauhan, Jesse McClure, Jessica Hekman, Patrick W. Marsh, Jeffrey A. Bailey, Rachel F. Daniels, Diane P. Genereux, Elinor K. Karlsson
Publikováno v:
Frontiers in Genetics, Vol 10 (2020)
The prevalence of tickborne diseases worldwide is increasing virtually unchecked due to the lack of effective control strategies. The transmission dynamics of tickborne pathogens are influenced by the tick microbiome, tick co-infection with other pat
Externí odkaz:
https://doaj.org/article/113e4633ff824fed812326606ef3c65b
Autor:
Yu Bin Na, Ozkan Aydemir, Mariusz Wojnarski, Michele D. Spring, Patrick W Marsh, Zackary Park, Panita Gosi, Andreea Waltmann, David L. Saunders, Chanthap Lon, Somethy Sok, Kara A. Moser, Nicholas F Brazeau, Jessica T. Lin, Meredith S. Muller, Jeffrey A. Bailey
Publikováno v:
Antimicrobial Agents and Chemotherapy. 65
Atovaquone-proguanil remains effective against multidrug-resistant Plasmodium falciparum in Southeast Asia, but resistance is mediated by a single point mutation in cytochrome b (cytb) that can arise during treatment. Among 14 atovaquone-proguanil tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a77d3116a0530a90c1ffaf0793aa47
https://doi.org/10.1128/aac.01249-20
https://doi.org/10.1128/aac.01249-20
Autor:
Anita Ghansah, Benjamin Abuaku, James L. Myers-Hansen, Benedicta A. Mensah, Ozkan Aydemir, Jeffrey A. Bailey, Patrick W Marsh
Publikováno v:
PeerJ
PeerJ, Vol 9, p e11794 (2021)
PeerJ, Vol 9, p e11794 (2021)
Antimalarial resistance surveillance in sub-Saharan Africa is often constrained by logistical and financial challenges limiting its breadth and frequency. At two sites in Ghana, we have piloted a streamlined sample pooling process created immediately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e42797380bf3384dad81d0e92b13b0
https://pubmed.ncbi.nlm.nih.gov/34820155
https://pubmed.ncbi.nlm.nih.gov/34820155
Autor:
Jessica T, Lin, Andreea, Waltmann, Kara A, Moser, Zackary, Park, Yu Bin, Na, Ozkan, Aydemir, Nicholas F, Brazeau, Panita, Gosi, Patrick W, Marsh, Meredith S, Muller, Michele, Spring, Somethy, Sok, Jeffrey A, Bailey, David L, Saunders, Chanthap, Lon, Mariusz, Wojnarski
Publikováno v:
Antimicrob Agents Chemother
Atovaquone-proguanil remains effective against multidrug-resistant Plasmodium falciparum in Southeast Asia, but resistance is mediated by a single point mutation in cytochrome b (cytb) that can arise during treatment. Among 14 atovaquone-proguanil tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a87edfa8f7272a70a17391e71f3df792
https://pubmed.ncbi.nlm.nih.gov/33361308
https://pubmed.ncbi.nlm.nih.gov/33361308
Autor:
Robert Verity, Rashid A. Madebe, Linda Mlunde, Erik Reaves, Billy Ngasala, Abdunoor M. Kabanywanyi, Frank Chaky, Patrick W Marsh, Ozkan Aydemir, Madeline Denton, Deus S. Ishengoma, Susan F. Rumisha, Ritha Njau, Chonge Kitojo, Erasmus Kamugisha, Marian Warsame, Oliver J Watson, Sigsbert Mkude, Reginald A. Kavishe, George Greer, Fabrizio Molteni, Celine I. Mandara, Jonathan J. Juliano, Dunstan Bishanga, Muhidin K. Mahende, Kara A. Moser, Mercy G. Chiduo, Maimuna Ahmed, Ally Mohamed, Jeffrey A. Bailey, Renata Mandike
Publikováno v:
Mol Ecol
High-throughput Plasmodium genomic data is increasingly useful in assessing prevalence of clinically important mutations and malaria transmission patterns. Understanding parasite diversity is important for identification of specific human or parasite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1cdf8cdcf17fdeb580f29fb79889d6
https://doi.org/10.1101/2020.05.09.085225
https://doi.org/10.1101/2020.05.09.085225
Autor:
James L. Myers-Hansen, Benedicta A. Mensah, Patrick W Marsh, Anita Ghansah, Jeffrey A. Bailey, Nicholas J. Hathaway, Ozkan Aydemir, Benjamin Abuaku, Millicent Opoku, Francis Anto
Publikováno v:
Antimicrob Agents Chemother
A key drawback to monitoring the emergence and spread of antimalarial drug resistance in sub-Saharan Africa is early detection and containment. Next-generation sequencing methods offer the resolution, sensitivity, and scale required to fill this gap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2e80ace1958e8f3c42dce2d64d0a9f
https://pubmed.ncbi.nlm.nih.gov/31932374
https://pubmed.ncbi.nlm.nih.gov/31932374
Autor:
Nicholas J. Hathaway, Patrick W Marsh, Nicholas F Brazeau, Patrick K Tumwebaze, Jonathan B. Parr, Melchior Kashamuka Mwandagalirwa, Azra C. Ghani, Travis Fulton, James L. Myers-Hansen, Jonathan J. Juliano, Steven R Meshnick, Julie Gutman, William J. Moss, Robert Verity, Jeffrey A. Bailey, Modest Mulenga, Deus S. Ishengoma, Jeremiah Ngondi, Melissa D. Conrad, Douglas E. Norris, Anita Ghansah, Andrew P. Morgan, Philip J. Rosenthal, Ozkan Aydemir, Benedicta A. Mensah, Kyaw L. Thwai, Oliver J Watson, Antoinette K. Tshefu, Madeline Denton
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications
The Democratic Republic of the Congo (DRC) harbors 11% of global malaria cases, yet little is known about the spatial and genetic structure of the parasite population in that country. We sequence 2537 Plasmodium falciparum infections, including a nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9411a4e19cc64b3e1bede174c4cbbb
https://doi.org/10.1101/656561
https://doi.org/10.1101/656561
Autor:
Frank Bearoff, Patrick W Marsh, Elizabeth P. Blankenhorn, Åke Lernmark, Ozkan Aydemir, Janelle A. Noble, Jeffrey A. Bailey, John P. Mordes, Agnes Andersson Svärd
Publikováno v:
Diabetes
Type 1 diabetes (T1D) involves the interaction of multiple gene variants, environmental factors, and immunoregulatory dysfunction. Major T1D genetic risk loci encode HLA-DR and -DQ. Genetic heterogeneity and linkage disequilibrium in the highly polym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c58011882c7a3bda6a882a15599e6bb
https://europepmc.org/articles/PMC6609989/
https://europepmc.org/articles/PMC6609989/