Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Patrick W Hanley"'
Autor:
Paige Fletcher, Chad S Clancy, Kyle L O'Donnell, Brianna M Doratt, Delphine C Malherbe, Joseph F Rhoderick, Friederike Feldmann, Patrick W Hanley, Ayato Takada, Ilhem Messaoudi, Andrea Marzi
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012290 (2024)
Taï Forest virus (TAFV) is a negative-sense RNA virus in the Filoviridae family. TAFV has caused only a single human infection, but several disease outbreaks in chimpanzees have been linked to this virus. Limited research has been done on this human
Externí odkaz:
https://doaj.org/article/6cdcafda9edb4689a6f82abbd530c61b
Autor:
Rebecca M Broeckel, Friederike Feldmann, Kristin L McNally, Abhilash I Chiramel, Gail L Sturdevant, Jacqueline M Leung, Patrick W Hanley, Jamie Lovaglio, Rebecca Rosenke, Dana P Scott, Greg Saturday, Fadila Bouamr, Angela L Rasmussen, Shelly J Robertson, Sonja M Best
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1009678 (2021)
Kyasanur Forest disease virus (KFDV) and the closely related Alkhurma hemorrhagic disease virus (AHFV) are emerging flaviviruses that cause severe viral hemorrhagic fevers in humans. Increasing geographical expansion and case numbers, particularly of
Externí odkaz:
https://doaj.org/article/e75b0f0e8a774ab2b7bf41f32357fe43
Autor:
Scott L Nuismer, Christopher H Remien, Andrew J Basinski, Tanner Varrelman, Nathan Layman, Kyle Rosenke, Brian Bird, Michael Jarvis, Peter Barry, Patrick W Hanley, Elisabeth Fichet-Calvet
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 9, p e0007920 (2020)
Lassa virus is a significant burden on human health throughout its endemic region in West Africa, with most human infections the result of spillover from the primary rodent reservoir of the virus, the natal multimammate mouse, M. natalensis. Here we
Externí odkaz:
https://doaj.org/article/05aae84dc3084d4e8da061756aece8e5
Autor:
Pramod N Nehete, Patrick W Hanley, Bharti P Nehete, Guojun Yang, Julio C Ruiz, Lawrence Williams, Christian R Abee, K Jagannadha Sastry
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79836 (2013)
Due to many physiological and genetic characteristic similarities to humans, squirrel monkeys provide an ideal animal model specifically for studying malaria, and transmissible spongiform encephalopathies (Creutzfeldt-Jacob disease). While squirrel m
Externí odkaz:
https://doaj.org/article/cc31f8c914e44ae8acfa126c3338e984
Autor:
Eric A Weaver, Pramod N Nehete, Bharti P Nehete, Guojun Yang, Stephanie J Buchl, Patrick W Hanley, Donna Palmer, David C Montefiori, Guido Ferrari, Philip Ng, K Jagannadha Sastry, Michael A Barry
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67574 (2013)
Most HIV-1 infections are thought to occur at mucosal surfaces during sexual contact. It has been hypothesized that vaccines delivered at mucosal surfaces may mediate better protection against HIV-1 than vaccines that are delivered systemically. To t
Externí odkaz:
https://doaj.org/article/5ffa11f663e248b9a83ae41302d80f5d
Autor:
Paige Fletcher, Kyle L. O’Donnell, Brianna M. Doratt, Delphine C. Malherbe, Chad S. Clancy, Joseph F. Rhoderick, Friederike Feldmann, Patrick W. Hanley, Thomas G. Ksiazek, Thomas W. Geisbert, Ilhem Messaoudi, Andrea Marzi
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Taï Forest virus (TAFV) is a lesser-known ebolavirus that causes lethal infections in chimpanzees and is responsible for a single human case. Limited research has been done on this human pathogen; however, with the recent emergence of filoviruses in
Externí odkaz:
https://doaj.org/article/f1a3f2fcd8214a4ba60d2e193a246435
Autor:
Thomas P. Monath, Richard Nichols, Friederike Feldmann, Amanda Griffin, Elaine Haddock, Julie Callison, Kimberly Meade-White, Atsushi Okumura, Jamie Lovaglio, Patrick W. Hanley, Chad S. Clancy, Carl Shaia, Wasima Rida, Joan Fusco
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionImmune correlates of protection afforded by PHV02, a recombinant vesicular stomatitis (rVSV) vector vaccine against Nipah virus (NiV) disease, were investigated in the African green monkey (AGM) model. Neutralizing antibody to NiV has bee
Externí odkaz:
https://doaj.org/article/040301b818554706ad4fda037c526189
Autor:
Neeltje van Doremalen, Victoria A. Avanzato, Kerry Goldin, Friederike Feldmann, Jonathan E. Schulz, Elaine Haddock, Atsushi Okumura, Jamie Lovaglio, Patrick W. Hanley, Kathleen Cordova, Greg Saturday, Emmie de Wit, Teresa Lambe, Sarah C. Gilbert, Vincent J. Munster
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Nipah virus (NiV) is a highly pathogenic and re-emerging virus, which causes sporadic but severe infections in humans. Currently, no vaccines against NiV have been approved. We previously showed that ChAdOx1 NiV provides full protection agai
Externí odkaz:
https://doaj.org/article/83a42009c7d8459eafa1e723eb0e5001
Autor:
Kyle L. O'Donnell, Friederike Feldmann, Benjamin Kaza, Chad S. Clancy, Patrick W. Hanley, Paige Fletcher, Andrea Marzi
Publikováno v:
EBioMedicine, Vol 89, Iss , Pp 104463- (2023)
Summary: Background: Marburg virus (MARV) is the causative agent of Marburg virus disease (MVD) which has a case fatality rate up to ∼90% in humans. Recently, there were cases reported in Guinea and Ghana highlighting this virus as a high-consequen
Externí odkaz:
https://doaj.org/article/220c79f91dff4870adbf1107b039130d
Autor:
Danielle R. Adney, Jamie Lovaglio, Jonathan E. Schulz, Claude Kwe Yinda, Victoria A. Avanzato, Elaine Haddock, Julia R. Port, Myndi G. Holbrook, Patrick W. Hanley, Greg Saturday, Dana Scott, Carl Shaia, Andrew M. Nelson, Jessica R. Spengler, Cassandra Tansey, Caitlin M. Cossaboom, Natalie M. Wendling, Craig Martens, John Easley, Seng Wai Yap, Stephanie N. Seifert, Vincent J. Munster
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
An animal model that fully recapitulates severe COVID-19 presentation in humans has been a top priority since the discovery of SARS-CoV-2 in 2019. Although multiple animal models are available for mild to moderate clinical disease, models that develo
Externí odkaz:
https://doaj.org/article/031af6abe49245eab4d9857ca6bed35e