Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Patrick W Hales"'
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75717 (2013)
The ability to assess brain tumor perfusion and abnormalities in the vascular structure in vivo could provide significant benefits in terms of lesion diagnosis and assessment of treatment response. Arterial spin labeling (ASL) has emerged as an incre
Externí odkaz:
https://doaj.org/article/1df08e5ceafb4fa69aa6f653f1c391c9
Autor:
Russell Murdoch, Hanne Stotesbury, Patrick W. Hales, Jamie M. Kawadler, Melanie Kölbel, Christopher A. Clark, Fenella J. Kirkham, Karin Shmueli
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
In recent years, interest has grown in the potential for magnetic resonance imaging (MRI) measures of venous oxygen saturation (Yv) to improve neurological risk prediction. T2-relaxation-under-spin-tagging (TRUST) is an MRI technique which has reveal
Externí odkaz:
https://doaj.org/article/66f8a0d4fead491e8235da54a7a7e257
Autor:
Hanne Stotesbury, Patrick W. Hales, Anna M. Hood, Melanie Koelbel, Jamie M. Kawadler, Dawn E. Saunders, Sati Sahota, David C. Rees, Olu Wilkey, Mark Layton, Maria Pelidis, Baba P. D. Inusa, Jo Howard, Subarna Chakravorty, Chris A. Clark, Fenella J. Kirkham
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Previous studies have pointed to a role for regional cerebral hemodynamic stress in neurological complications in patients with sickle cell anemia (SCA), with watershed regions identified as particularly at risk of ischemic tissue injury. Using singl
Externí odkaz:
https://doaj.org/article/72f7c88f701c47aea7fb2b9583d683dc
Autor:
Natalie R. Boonzaier, Patrick W. Hales, Felice D'Arco, Bronwen C. Walters, Ramneek Kaur, Kshitij Mankad, Jessica Cooper, Alki Liasis, Victoria Smith, Patricia O'Hare, Darren Hargrave, Christopher A. Clark
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102447- (2020)
Background: The subventricular zone of the third ventricle (TVZ) is a germinal stem cell niche, identified as the possible location of optic pathway glioma (OPG) cell origin. Paediatric OPGs are predominantly diagnosed as low-grade astrocytomas, whic
Externí odkaz:
https://doaj.org/article/61a189f666f04397863aa0c2d55d4c34
Autor:
Hanne Stotesbury, Patrick W Hales, Melanie Koelbel, Anna M Hood, Jamie M Kawadler, Dawn E Saunders, Sati Sahota, David C Rees, Olu Wilkey, Mark Layton, Maria Pelidis, Baba PD Inusa, Jo Howard, Subarna Chakravorty, Chris A Clark, Fenella J Kirkham
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 42:1061-1077
Prior studies have described high venous signal qualitatively using arterial spin labelling (ASL) in patients with sickle cell anemia (SCA), consistent with arteriovenous shunting. We aimed to quantify the effect and explored cross-sectional associat
Publikováno v:
Magnetic resonance materials in physics biology and medicine, 34, 261-271. SPRINGER
Magma (New York, N.y.)
Magma (New York, N.y.)
Objective ADC (Apparent Diffusion Coefficient) derived from Diffusion-Weighted Imaging (DWI) has shown promise as a non-invasive quantitative imaging biomarker in Wilms’ tumours. However, many non-Gaussian models could be applied to DWI. This study
Autor:
Dorothee P. Auer, Shivaram Avula, Chris A. Clark, Ramneek Kaur, Simon Bailey, Tim Jaspan, Heather E. L. Rose, Darren Hargrave, Laurence Abernethy, Patrick W. Hales, Theodoros N. Arvanitis, Adam Oates, Daniel Rodriguez Gutierrez, Jan Novak, Lesley MacPherson, Nigel P. Davies, Richard Grundy, Benjamin Pinkey, Dipayan Mitra, Niloufar Zarinabad, Andrew C. Peet
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
To determine if apparent diffusion coefficients (ADC) can discriminate between posterior fossa brain tumours on a multicentre basis. A total of 124 paediatric patients with posterior fossa tumours (including 55 Medulloblastomas, 36 Pilocytic Astrocyt
Autor:
Christopher Clark, Luis Miguel Lacerda, Kristian Aquilina, Sebastian Toescu, Enrico Kaden, Patrick W. Hales
Publikováno v:
Cerebral Cortex. 31:2595-2609
The dentato-rubro-thalamo-cortical tract (DRTC) is the main outflow pathway of the cerebellum, contributing to a finely balanced corticocerebellar loop involved in cognitive and sensorimotor functions. Damage to the DRTC has been implicated in cerebe
Autor:
Giuseppe Barone, Kate Cross, Paul D. Humphries, Layla Musleh, Laura Privitera, Elizabeth Morris, Stefano Giuliani, Lorenzo Biassoni, Natalie Sizer, Patrick W. Hales
Publikováno v:
Journal of Magnetic Resonance Imaging. 53:1486-1497
Background: High-risk neuroblastoma (HR-NB) has a variable response to preoperative chemotherapy. It is not possible to differentiate viable vs. nonviable residual tumor before surgery. Purpose: To explore the association between apparent diffusion c
Publikováno v:
Journal of Magnetic Resonance Imaging. 52:1413-1426
BACKGROUND Arterial spin labeling (ASL) is a useful tool for measuring cerebral blood flow (CBF). However, due to the low signal-to-noise ratio (SNR) of the technique, multiple repetitions are required, which results in prolonged scan times and incre