Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Patrick Viatour"'
Autor:
Eunsun Kim, Amanda Lisby, Connie Ma, Nathanael Lo, Ursula Ehmer, Katharina E. Hayer, Emma E. Furth, Patrick Viatour
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Aberrant Wnt/b-catenin signaling is thought to be a major driver of hepatocellular carcinoma. Here, the authors show that β-Catenin is predominantly integrated within the AJ complex during the early stages of this cancer and enhance EGFR signaling t
Externí odkaz:
https://doaj.org/article/23d83511c5b14bb7b618f8c1a6766131
Autor:
Rebecca Windmueller, John P. Leach, Apoorva Babu, Su Zhou, Michael P. Morley, Aoi Wakabayashi, Nataliya B. Petrenko, Patrick Viatour, Edward E. Morrisey
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 3105-3116.e4 (2020)
Summary: The mammalian heart is incapable of regenerating a sufficient number of cardiomyocytes to ameliorate the loss of contractile muscle after acute myocardial injury. Several reports have demonstrated that mononucleated cardiomyocytes are more r
Externí odkaz:
https://doaj.org/article/4cc9d514ae934b469d3b2fc8c7e2809f
Autor:
Patrick Viatour, Julien Sage
Publikováno v:
Disease Models & Mechanisms, Vol 4, Iss 5, Pp 581-585 (2011)
The retinoblastoma (RB) tumor suppressor belongs to a cellular pathway that plays a crucial role in restricting the G1-S transition of the cell cycle in response to a large number of extracellular and intracellular cues. Research in the last decade h
Externí odkaz:
https://doaj.org/article/3cc79505b8b24c24840083cb244e9642
Autor:
Jesús M Paramio, Federico de la Rosa, Jose L. Rodriguez-Peralto, Daniel Castellano, Julien Sage, Miguel A. Morcillo, Patrick Viatour, Manoli Fernández, Ma Luisa Martín, Ma José Gómez-Rodriguez, Victor Martínez, José Duarte, Marta Oteo, Clotilde Costa, Cristina Saiz-Ladera, Felipe Villacampa, Begoña Alfaya, Ramón García-Escudero, Marta Dueñas, Mónica Martínez-Fernández, Mirentxu Santos
Supp Table S12. Gene Ontology of Biological processes of the upregulated genes in human recurrent bladder tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff4c6c9d195c7ffb1ea85f97324adf8
https://doi.org/10.1158/0008-5472.22403774
https://doi.org/10.1158/0008-5472.22403774
Autor:
Jesús M Paramio, Federico de la Rosa, Jose L. Rodriguez-Peralto, Daniel Castellano, Julien Sage, Miguel A. Morcillo, Patrick Viatour, Manoli Fernández, Ma Luisa Martín, Ma José Gómez-Rodriguez, Victor Martínez, José Duarte, Marta Oteo, Clotilde Costa, Cristina Saiz-Ladera, Felipe Villacampa, Begoña Alfaya, Ramón García-Escudero, Marta Dueñas, Mónica Martínez-Fernández, Mirentxu Santos
Supplementary Information. Supplementary Methods Supplementary Figures 1-6. Supp Fig. 1: Identification of bladder tumors by Computerized tomography (CT). Supp Fig 2: Determination of effective elimination of pRb and p130 in bladder tumors. Supp Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ce56bf4f0fb362292cce9c31932ba2
https://doi.org/10.1158/0008-5472.22403744
https://doi.org/10.1158/0008-5472.22403744
Autor:
Eunsun Kim, Patrick Viatour
Publikováno v:
Experimental & Molecular Medicine
Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and a leading cause of cancer-related deaths worldwide. Ninety percent of HCC cases arise from cirrhosis, during which liver cells undergo chronic cycles of necrosis and regene
Autor:
John Leach, Michael Morley, Aoi Wakabayashi, Rebecca Windmueller, Apoorva Babu, Edward E. Morrisey, Nataliya B. Petrenko, Su Zhou, Patrick Viatour
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 3105-3116.e4 (2020)
Cell reports
Cell reports
SUMMARY The mammalian heart is incapable of regenerating a sufficient number of cardiomyocytes to ameliorate the loss of contractile muscle after acute myocardial injury. Several reports have demonstrated that mononucleated cardiomyocytes are more re
Autor:
Amy Tarangelo, Gerald Wertheim, Elisabeth Bolton-Gillespie, Katharina E. Hayer, Madhumita Jambhekar, Ying Cheng, Linh Le, Connie Ma, Xiongwei Cai, Patrick Viatour, Wei Tong, Pichai Raman, Nancy A. Speck, Eunsun Kim
Publikováno v:
The Journal of Experimental Medicine
The mechanisms regulating the homeostasis of HSCs remain poorly understood. Here, Kim et al. identify the Rb/E2f module as a central molecular hub in the regulation of cell cycle and homeostasis in HSCs. This mechanism drives the enforced differentia
Autor:
Connie Ma, Katharina E. Hayer, Emma E. Furth, Nathanael Lo, Patrick Viatour, Eunsun Kim, Ursula Ehmer, Amanda Lisby
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. β-catenin is widely thought to be a major oncogene in HCC based on the frequency of mutations associated with aberrant Wnt signaling in HCC patients. Chal
Autor:
Thomas Serwold, Ellen R. Richie, Jerrod L. Bryson, Phillip M. Garfin, Nancy R. Manley, Dullei Min, C. Clare Blackburn, Julien Sage, Badreddin Edris, Kenneth I. Weinberg, Patrick Viatour
Publikováno v:
The Journal of Experimental Medicine
RB family genes control T cell production and promote thymic involution through reducing Foxn1 expression in thymic epithelial cells.
Thymic involution during aging is a major cause of decreased production of T cells and reduced immunity. Here w
Thymic involution during aging is a major cause of decreased production of T cells and reduced immunity. Here w