Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Patrick Varilly"'
Autor:
Pardis C Sabeti, Emily Walsh, Steve F Schaffner, Patrick Varilly, Ben Fry, Holli B Hutcheson, Mike Cullen, Tarjei S Mikkelsen, Jessica Roy, Nick Patterson, Richard Cooper, David Reich, David Altshuler, Stephen O'Brien, Eric S Lander
Publikováno v:
PLoS Biology, Vol 3, Iss 11, p e378 (2005)
The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Delta32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-Delta32 arose within the past 1,000 y and rose to its present high frequ
Externí odkaz:
https://doaj.org/article/08cd36e6040b4450862144729a1f1a28
Autor:
Patrick Varilly, Jure Dobnikar, Francisco J. Martinez-Veracoechea, Bortolo Matteo Mognetti, Stefano Angioletti-Uberti, Daan Frenkel
Publikováno v:
Soft Matter
Colloidal particles with DNA `legs' that can bind reversibly to receptors on a surface can be made to `walk' if there is a gradient in receptor concentration. We use a combination of theory and Monte Carlo simulations to explore how controllable para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31892aa68d62072ad17673e25d65647d
Autor:
Amish J. Patel, David Chandler, Michael F. Hagan, Shekhar Garde, Sumanth N. Jamadagni, Patrick Varilly
Publikováno v:
The Journal of Physical Chemistry B. 116:2498-2503
Water near hydrophobic surfaces is like that at a liquid-vapor interface, where fluctuations in water density are substantially enhanced compared to that in bulk water. Here we use molecular simulations with specialized sampling techniques to show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3bb012f84e8d76c3df39acdc97ae6f
https://doi.org/10.1021/jp2107523
https://doi.org/10.1021/jp2107523
Autor:
Amish J. Patel, David Chandler, Hari Acharya, Sumanth N. Jamadagni, Patrick Varilly, Shekhar Garde
Publikováno v:
Proceedings of the National Academy of Sciences. 108:17678-17683
Interfaces are a most common motif in complex systems. To understand how the presence of interfaces affects hydrophobic phenomena, we use molecular simulations and theory to study hydration of solutes at interfaces. The solutes range in size from sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf4ed75ceffcddb08b32dd75e598e69
https://doi.org/10.1073/pnas.1110703108
https://doi.org/10.1073/pnas.1110703108
Publikováno v:
Advances in Mathematics. 228(3):1377-1404
We construct an explicit K3 surface over the field of rational numbers that has geometric Picard rank one, and for which there is a transcendental Brauer-Manin obstruction to weak approximation. To do so, we exploit the relationship between polarized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104d37bc831fea27f827b124f19ee466
Autor:
Mark Leppert, Aravinda Chakravarti, Charmaine D.M. Royal, Sarah S. Murray, Renzong Qiu, Panos Deloukas, Renwu Wang, David A. Hinds, Barbara E. Stranger, Xiaoli Tang, Huanming Yang, John W. Belmont, Nigel P. Carter, Huy Nguyen, William Mak, Kazuto Kato, Shiran Pasternak, Chaohua Li, Jeffrey C. Barrett, Lon R. Cardon, Vincent Ferretti, Atsushi Nagashima, Peter E. Chen, Stephen F. Schaffner, Hongbo Fu, Zhu Chen, Siqi Liu, John Burton, Paul Hardenbol, Gudmundur A. Thorisson, Yusuke Nakamura, Mark Griffiths, Imtiaz Yakub, Eiko Suda, Gonçalo R. Abecasis, Carl S. Kashuk, Qingrun Zhang, Yoshimitsu Fukushima, Karen Kennedy, Sarah E. Hunt, Yi Wang, Norio Niikawa, Ichiro Matsuda, Lynn F. Zacharia, Lalitha Krishnan, Zhen Wang, Stéphanie Roumy, C M Clee, David J. Cutler, Albert V. Smith, Lincoln Stein, Simon Myers, Jane Peterson, Jun Zhou, Yozo Ohnishi, Weihua Guan, Matthew Stephens, Xiaoyan Xiong, Julian Maller, Houcan Zhang, Pui-Yan Kwok, Mark S. Guyer, Liuda Ziaugra, Jonathan Witonsky, Matthew C. Jones, Stacey Gabriel, You-Qiang Song, Daochang An, Haifeng Wang, Gilean McVean, Lawrence M. Sung, Zhijian Yao, Yan Shen, Yangfan Liu, George M. Weinstock, Ludmila Pawlikowska, Erica Sodergren, Mark T. Ross, Andrew Boudreau, Toshihiro Tanaka, Thomas D. Willis, Weitao Hu, Kelly A. Frazer, Li Jin, Robert W. Plumb, Paul I.W. de Bakker, Hongbin Zhao, Wei Lin, Sarah Sims, Richard A. Gibbs, Maura Faggart, Michael Feolo, Dennis G. Ballinger, Xun Chu, Lucinda Fulton, Marcos Delgado, Ellen Winchester, Wei Huang, Fuli Yu, Christianne R. Bird, Shaun Purcell, Jessica Roy, Dongmei Cai, Launa M. Galver, Bartha Maria Knoppers, Emmanouil T. Dermitzakis, Gao Yang, Takashi Morizono, Rachel Barry, Kirsten McLay, Daryl J. Thomas, Steve McCarroll, Jonathan Marchini, Daniel J. Richter, Andy Peiffer, Patricia Taillon-Miller, Richard K. Wilson, Stephen Kwok-Wing Tsui, Jian-Bing Fan, Lisa D. Brooks, Laura L. Stuve, Paul L'Archevêque, David M. Evans, Clémentine Sallée, Peter Donnelly, Hong Xue, Hui Zhao, Charles N. Rotimi, Jean E. McEwen, J. Tze Fei Wong, Hao Pan, Alastair Kent, Brendan Blumenstiel, Qing Li, Weiwei Sun, L. Kang, Colin Freeman, John Stewart, Chibuzor Nkwodimmah, Morris W. Foster, Don Powell, Leonardo Bottolo, Raymond D. Miller, Stephen T. Sherry, Francis S. Collins, Donna M. Muzny, Jun Yu, Ike Ajayi, Hua Han, Pardis C. Sabeti, Hongguang Wang, Takahisa Kawaguchi, Tatsuhiko Tsunoda, Guy Bellemare, Zhaohui S. Qin, H. B. Hu, Jane Rogers, Thomas J. Hudson, Mark J. Daly, Andrew P. Morris, Supriya Gupta, Ming Xiao, Patrick Varilly, Nick Patterson, Akihiro Sekine, Chris C. A. Spencer, Jonathan Morrison, Missy Dixon, Paul K.H. Tam, Jian Wang, Matthew Defelice, Susana Eyheramendy, Michael Shi, Yungang He, Ellen Wright Clayton, Richa Saxena, Heather M. Munro, Arthur L. Holden, Yayun Shen, Christine P. Bird, Bruce W. Birren, Itsik Pe'er, David R. Bentley, Lynne V. Nazareth, Pamela Whittaker, Pak C. Sham, Amy L. Camargo, David A. Wheeler, Koji Saeki, Martin Godbout, David Altshuler, Liang Xu, Ying Wang, David Willey, Alexandre Montpetit, Shin Lin, Michael S. Phillips, Changqing Zeng, Clement Adebamowo, John C. Wallenburg, Mark S. Chee, Ben Fry, Erich Stahl, Melissa Parkin, Rhian Gwilliam, Andrei Verner, Patrick J. Nailer, Lap-Chee Tsui, Bo Zhang, Fanny Chagnon, David R. Cox, Jack Spiegel, Jamie Moore, Vivian Ota Wang, Patricia A. Marshall, Takuya Kitamoto, Bruce S. Weir, Darryl Macer, Geraldine M. Clarke, Robert C. Onofrio, Mary M.Y. Waye, Wei Wang, Suzanne M. Leal, James C. Mullikin, Toyin Aniagwu, Daniel C. Koboldt, Mary Goyette, Martin Leboeuf, Isaac F. Adewole, Ruth Jamieson, Arnold Oliphant, Jessica Watkin, Jean François Olivier
Publikováno v:
Europe PubMed Central
Inherited genetic variation has a critical but as yet largely uncharacterized role in human disease. Here we report a public database of common variation in the human genome: more than one million single nucleotide polymorphisms (SNPs) for which accu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f411640f26dad2af5d9b0f5040008937
https://doi.org/10.1038/nature04226
https://doi.org/10.1038/nature04226
Autor:
Lorenzo Di Michele, Erika Eiser, Taiki Yanagishima, Zachary Ruff, Daan Frenkel, Patrick Varilly, Bortolo Matteo Mognetti
Publikováno v:
Journal of the American Chemical Society
The selective hybridization of DNA is of key importance for many practical applications such as gene detection and DNA-mediated self-assembly. These applications require a quantitative prediction of the hybridization free energy. Existing methods ign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f6069b567002cadda933fb05eac7d9
Autor:
Alexei V. Tkachenko, Patrick Varilly, Bortolo Matteo Mognetti, Stefano Angioletti-Uberti, Daan Frenkel
Recently [P. Varilly, S. Angioletti-Uberti, B. M. Mognetti, and D. Frenkel, "A general theory of DNA-mediated and other valence-limited colloidal interactions," J. Chem. Phys. 137, 094108 (2012)], we presented a general theory for calculating the str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8171c58ac3bd2ddc55fcc6c7bd58b1
http://hdl.handle.net/10044/1/60550
http://hdl.handle.net/10044/1/60550
Autor:
David Chandler, Patrick Varilly
We use transition path sampling to study evaporation in the SPC/E model of liquid water. Based on thousands of evaporation trajectories, we characterize the members of the transition state ensemble (TSE), which exhibit a liquid-vapor interface with p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffef7aac1d6cc6215505d281a96c005
http://arxiv.org/abs/1210.3158
http://arxiv.org/abs/1210.3158
Autor:
Jure Dobnikar, Mirjam E. Leunissen, Bortolo Matteo Mognetti, Stefano Angioletti-Uberti, Patrick Varilly, Daan Frenkel, Francisco J. Martinez-Veracoechea
Publikováno v:
Proceedings of the National Academy of Sciences
DNA bridging can be used to induce specific attractions between small particles, providing a highly versatile approach to creating unique particle-based materials having a variety of periodic structures. Surprisingly, given the fact that the thermody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c853d8a4ed4100e4b9d65275dab718
https://pubmed.ncbi.nlm.nih.gov/21896714
https://pubmed.ncbi.nlm.nih.gov/21896714