Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Patrick Varga-Weisz"'
Autor:
Renan Oliveira Corrêa, Pollyana Ribeiro Castro, José Luís Fachi, Vinícius Dias Nirello, Salma El-Sahhar, Shinya Imada, Gabriel Vasconcelos Pereira, Laís Passariello Pral, Nathália Vitoria Pereira Araújo, Mariane Font Fernandes, Valquíria Aparecida Matheus, Jaqueline de Souza Felipe, Arilson Bernardo dos Santos Pereira Gomes, Sarah de Oliveira, Vinícius de Rezende Rodovalho, Samantha Roberta Machado de Oliveira, Helder Carvalho de Assis, Sergio Costa Oliveira, Flaviano Dos Santos Martins, Eric Martens, Marco Colonna, Patrick Varga-Weisz, Marco Aurélio Ramirez Vinolo
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-25 (2023)
Abstract Background The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions. How these processes ar
Externí odkaz:
https://doaj.org/article/8662c6ab735449e096273c702971b2ee
Autor:
Debanjan Mukherjee, Ângelo Ferreira Chora, Jean-Christophe Lone, Ricardo S. Ramiro, Birte Blankenhaus, Karine Serre, Mário Ramirez, Isabel Gordo, Marc Veldhoen, Patrick Varga-Weisz, Maria M. Mota
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The reasons why malaria manifests with a variety of well-recognized clinical phenotypes remain poorly understood. Here, using distinct rodent models, the authors reveal that the microbiota colonizing the lung promotes respiratory distress syndrome an
Externí odkaz:
https://doaj.org/article/52854a7861954b79a5a43d3d180094b1
Autor:
Renan Oliveira Corrêa, Pollyana Ribeiro Castro, José Luís Fachi, Vinícius Dias Nirello, Salma El‑Sahhar, Shinya Imada, Gabriel Vasconcelos Pereira, Laís Passariello Pral, Nathália Vitoria Pereira Araújo, Mariane Font Fernandes, Valquíria Aparecida Matheus, Jaqueline de Souza Felipe, Arilson Bernardo dos Santos Pereira Gomes, Sarah de Oliveira, Vinícius de Rezende Rodovalho, Samantha Roberta Machado de Oliveira, Helder Carvalho de Assis, Sergio Costa Oliveira, Flaviano Dos Santos Martins, Eric Martens, Marco Colonna, Patrick Varga‑Weisz, Marco Aurélio Ramirez Vinolo
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/81de1b7174d54b62870cee45b83f85ad
Autor:
Juri Kazakevych, Jérémy Denizot, Anke Liebert, Mariana Portovedo, Mia Mosavie, Payal Jain, Claudia Stellato, Claire Fraser, Renan Oliveira Corrêa, Marina Célestine, Raphaël Mattiuz, Hanneke Okkenhaug, J. Ross Miller, Marco Aurélio Ramirez Vinolo, Marc Veldhoen, Patrick Varga-Weisz
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-20 (2020)
Abstract Background How intestinal epithelial cells interact with the microbiota and how this is regulated at the gene expression level are critical questions. Smarcad1 is a conserved chromatin remodeling factor with a poorly understood tissue functi
Externí odkaz:
https://doaj.org/article/bc150fa4d28746ba8b0f4a6c65280385
Autor:
Rachel Fellows, Patrick Varga-Weisz
Publikováno v:
Molecular Metabolism, Vol 38, Iss , Pp 100925- (2020)
Background: The microbiota in the human gut are an important component of normal physiology that has co-evolved from the earliest multicellular organisms. Therefore, it is unsurprising that there is intimate crosstalk between the microbial world in t
Externí odkaz:
https://doaj.org/article/341fd4caf82a4192a067e94823ad95d8
Autor:
Rachel Fellows, Jérémy Denizot, Claudia Stellato, Alessandro Cuomo, Payal Jain, Elena Stoyanova, Szabina Balázsi, Zoltán Hajnády, Anke Liebert, Juri Kazakevych, Hector Blackburn, Renan Oliveira Corrêa, José Luís Fachi, Fabio Takeo Sato, Willian R. Ribeiro, Caroline Marcantonio Ferreira, Hélène Perée, Mariangela Spagnuolo, Raphaël Mattiuz, Csaba Matolcsi, Joana Guedes, Jonathan Clark, Marc Veldhoen, Tiziana Bonaldi, Marco Aurélio Ramirez Vinolo, Patrick Varga-Weisz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Histone post-translational modifications are known key regulators of gene expression. Here, the authors characterize histone crotonylation at histone H3 lysine 18 in intestinal epithelia and find that it is a highly dynamic cell cycle regulated mark
Externí odkaz:
https://doaj.org/article/dcb0d5694cd141d7940f735b72dfe7cb
Autor:
José Luís Fachi, Jaqueline de Souza Felipe, Laís Passariello Pral, Bruna Karadi da Silva, Renan Oliveira Corrêa, Mirella Cristiny Pereira de Andrade, Denise Morais da Fonseca, Paulo José Basso, Niels Olsen Saraiva Câmara, Éricka Lorenna de Sales e Souza, Flaviano dos Santos Martins, Suzana Eiko Sato Guima, Andrew Maltez Thomas, João Carlos Setubal, Yuli Thamires Magalhães, Fábio Luis Forti, Thamiris Candreva, Hosana Gomes Rodrigues, Marcelo Bispo de Jesus, Sílvio Roberto Consonni, Alessandro dos Santos Farias, Patrick Varga-Weisz, Marco Aurélio Ramirez Vinolo
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 750-761.e7 (2019)
Summary: Antibiotic-induced dysbiosis is a key factor predisposing intestinal infection by Clostridium difficile. Here, we show that interventions that restore butyrate intestinal levels mitigate clinical and pathological features of C. difficile-ind
Externí odkaz:
https://doaj.org/article/9c4fc043dfbe4f37bba8f567ccb37dd6
Autor:
Rachel Fellows, Patrick Varga-Weisz
Publikováno v:
Bio-Protocol, Vol 8, Iss 14 (2018)
Class I histone deacetylases (HDACs) are efficient histone decrotonylases, broadening the enzymatic spectrum of these important (epi-)genome regulators and drug targets. Here, we describe an in vitro approach to assaying class I HDACs with different
Externí odkaz:
https://doaj.org/article/1409ab374577498a87333aabfe3de3e9
Autor:
Mickaël Durand-Dubief, William Ryan Will, Edoardo Petrini, Delphine Theodorou, Rachael R Harris, Margaret R Crawford, Konrad Paszkiewicz, Felix Krueger, Rosa Maria Correra, Anna T Vetter, J Ross Miller, Nicholas A Kent, Patrick Varga-Weisz
Publikováno v:
PLoS Genetics, Vol 8, Iss 9, p e1002974 (2012)
Budding yeast centromeres are sequence-defined point centromeres and are, unlike in many other organisms, not embedded in heterochromatin. Here we show that Fun30, a poorly understood SWI/SNF-like chromatin remodeling factor conserved in humans, prom
Externí odkaz:
https://doaj.org/article/1c18367c0e4f4f648ec6bb71c293d135
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8111 (2009)
Chromatin regulates many key processes in the nucleus by controlling access to the underlying DNA. SNF2-like factors are ATP-driven enzymes that play key roles in the dynamics of chromatin by remodelling nucleosomes and other nucleoprotein complexes.
Externí odkaz:
https://doaj.org/article/f8c47b4e6b6a45129ca348a42fb7d9e5