Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Patrick Vanscheeuwijck"'
Autor:
Davide Sciuscio, Florian Calvino-Martin, Ashutosh Kumar, Timothy B. Langston, Elyette Martin, Diego Marescotti, Carole Mathis, Julia Hoeng, Manuel C. Peitsch, Donna C. Smith, Maria Gogova, Patrick Vanscheeuwijck, Kyeonghee M. Lee
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Many flavor ingredients are often used in potentially reduced-risk tobacco products (such as e-vapor products). Although most are “generally recognized as safe (GRAS)” when used in food, there is limited information available on their long-term h
Externí odkaz:
https://doaj.org/article/575444b99c4b40eba0477dc9cc873fcb
Autor:
Bjoern Titz, Justyna Szostak, Alain Sewer, Blaine Phillips, Catherine Nury, Thomas Schneider, Sophie Dijon, Oksana Lavrynenko, Ashraf Elamin, Emmanuel Guedj, Ee Tsin Wong, Stefan Lebrun, Grégory Vuillaume, Athanasios Kondylis, Sylvain Gubian, Stephane Cano, Patrice Leroy, Brian Keppler, Nikolai V. Ivanov, Patrick Vanscheeuwijck, Florian Martin, Manuel C. Peitsch, Julia Hoeng
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1056-1073 (2020)
Cigarette smoke (CS) causes adverse health effects and, for smoker who do not quit, modified risk tobacco products (MRTPs) can be an alternative to reduce the risk of developing smoking-related diseases. Standard toxicological endpoints can lack sens
Externí odkaz:
https://doaj.org/article/77141a5211234e6fa104ff9d225dbe21
Autor:
James N. D. Battey, Justyna Szostak, Blaine Phillips, Charles Teng, Ching Keong Tung, Wei Ting Lim, Ying Shan Yeo, Sonia Ouadi, Karine Baumer, Jerome Thomas, Jacopo Martinis, Nicolas Sierro, Nikolai V. Ivanov, Patrick Vanscheeuwijck, Manuel C. Peitsch, Julia Hoeng
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Cigarette smoking causes adverse health effects that might occur shortly after smoking initiation and lead to the development of inflammation and cardiorespiratory disease. Emerging studies have demonstrated the role of the intestinal microbiome in d
Externí odkaz:
https://doaj.org/article/cf5a173016994a20a52d5e33f9b0a25e
Autor:
Jean-Pierre Schaller, Daniela Keller, Laurent Poget, Pascal Pratte, Etienne Kaelin, Damian McHugh, Gianluca Cudazzo, Daniel Smart, Anthony R. Tricker, Lydia Gautier, Michel Yerly, Roger Reis Pires, Soazig Le Bouhellec, David Ghosh, Iris Hofer, Eva Garcia, Patrick Vanscheeuwijck, Serge Maeder
Publikováno v:
Romanian Medical Journal, Vol 65, Iss 4 (2018)
The chemical composition, in vitro genotoxicity, and cytotoxicity of the mainstream aerosol from the Tobacco Heating System 2.2 (THS2.2) were compared with those of the mainstream smoke from the 3R4F reference cigarette. In contrast to the 3R4F, the
Externí odkaz:
https://doaj.org/article/bf50851626a94b46922b5ba57ff23067
Autor:
Stéphanie Boué, Thomas Exner, Samik Ghosh, Vincenzo Belcastro, Joh Dokler, David Page, Akash Boda, Filipe Bonjour, Barry Hardy, Patrick Vanscheeuwijck, Julia Hoeng, Manuel Peitsch
Publikováno v:
F1000Research, Vol 6 (2017)
The US FDA defines modified risk tobacco products (MRTPs) as products that aim to reduce harm or the risk of tobacco-related disease associated with commercially marketed tobacco products. Establishing a product’s potential as an MRTP requires scie
Externí odkaz:
https://doaj.org/article/1eb426cd358c4e699f688f4d2eaef482
Autor:
Ee Tsin Wong, Karsta Luettich, Lydia Cammack, Chin Suan Chua, David Sciuscio, Celine Merg, Maica Corciulo, Romain Piault, Kumar Ashutosh, Cameron Smith, Patrice Leroy, Fabian Moine, Anneke Glabasnia, Pierrick Diana, Cecilia Chia, Ching Keong Tung, Nikolai Ivanov, Julia Hoeng, Manuel Peitsch, Kyeonghee Monica Lee, Patrick Vanscheeuwijck
Publikováno v:
Journal of Applied Toxicology. 42:1701-1722
Most flavors used in e-liquids are generally recognized as safe for oral consumption, but their potential effects when inhaled are not well characterized. In vivo inhalation studies of flavor ingredients in e-liquids are scarce. A structure-based gro
Autor:
Walter K. Schlage, Julia Hoeng, Dariusz Peric, Nicolas Sierro, John H. Miller, Ee Tsin Wong, Blaine Phillips, Justyna Szostak, Jingjie Zhang, Emmanuel Guedj, Patrick Vanscheeuwijck, Jovan Simicevic, Tom Lee, Manuel C. Peitsch, Patrice Leroy, Remi Dulize, Maica Corciulo, Oksana Lavrynenko, Yang Xiang, Kyeonghee Monica Lee, David Bornand, Bjoern Titz, Sin Kei Wong, Karsta Luettich, Mohamed Amin Choukrallah, Arkadiusz K. Kuczaj, Guo Jie Loh, Thomas Schneider, Nikolai V. Ivanov, Mehdi Auberson, Celine Merg, Ansgar Buettner
Publikováno v:
Archives of Toxicology
Cigarette smoking is the major cause of chronic obstructive pulmonary disease. Considerable attention has been paid to the reduced harm potential of nicotine-containing inhalable products such as electronic cigarettes (e-cigarettes). We investigated
Autor:
Wenhao Xia, Kyoko Koshibu, Blaine Phillips, Thomas Schneider, Arkadiusz K. Kuczaj, Kaing Woon, Marja Talikka, Athanasios Kondylis, Patrick Vanscheeuwijck, Charles Teng, Florian Martin, Glenda Tan, Aditya Reddy Kolli, Manuel C. Peitsch, Julia Hoeng, Wei Teck Tan, Ying Shan Yeo
Publikováno v:
Journal of Natural Products. 84:1012-1021
Natural alkaloids, a large class of plant-derived substances, have attracted considerable interest because of their pharmacological activities. In this study, the in vivo pharmacokinetics and anti-inflammatory profile of anatabine, a naturally occurr
Autor:
Julia Hoeng, Arkadiusz K. Kuczaj, Patrick Vanscheeuwijck, Subash Krishnan, Falk Radtke, Wei Teck Tan, Tom Lee, Francesco Lucci, Sandra Schorderet Weber, Didier Goedertier
Publikováno v:
Journal of Visualized Experiments.
The capillary aerosol generator (CAG) is operated with the principal of thermal liquid evaporation through heating of e-liquid in the initial phase, followed by nucleation and condensation regulated through a mixture of airflow to generate aerosols,
Autor:
Karsta Luettich, Patrick Vanscheeuwijck, Demetrius Yeo, Gregory Vuillaume, Wei Ting Lim, Ansgar Büttner, Patrice Leroy, Subash Krishnan, Stéphanie Boué, Julia Hoeng, Ee Tsin Wong, Manuel C. Peitsch, Sin Kei Wong
Publikováno v:
Toxicological Sciences
We conducted an inhalation study, in accordance with Organisation for Economic Co-operation and Development Test Guideline 453, exposing A/J mice to tobacco heating system (THS) 2.2 aerosol or 3R4F reference cigarette smoke (CS) for up to 18 months t