Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Patrick Van Zalm"'
Autor:
Kathrin Wenger, Arthur Viode, Christoph N. Schlaffner, Patrick van Zalm, Long Cheng, Tammy Dellovade, Xavier Langlois, Anthony Bannon, Rui Chang, Theresa R. Connors, Derek Oakley, Bernhard Renard, Juri Rappsilber, Bradley Hyman, Hanno Steen, Judith A. Steen
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-15 (2023)
Abstract Background Mouse models that overexpress human mutant Tau (P301S and P301L) are commonly used in preclinical studies of Alzheimer’s Disease (AD) and while several drugs showed therapeutic effects in these mice, they were ineffective in hum
Externí odkaz:
https://doaj.org/article/0d7d9b70fb6e432d8c9dc6d0e97c6577
Autor:
Arthur Viodé, Kinga K. Smolen, Benoit Fatou, Zainab Wurie, Patrick Van Zalm, Mandy Kader Konde, Balla Moussa Keita, Richard Amento Ablam, Eleanor N. Fish, Hanno Steen
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Ebola virus (EBV) disease (EVD) is a highly virulent systemic disease characterized by an aggressive systemic inflammatory response and impaired vascular and coagulation systems, often leading to uncontrolled hemorrhaging and death. In this
Externí odkaz:
https://doaj.org/article/624f8327b3f4481fbb8b444be734402a
Autor:
Saima Ahmed, Patrick van Zalm, Emily A. Rudmann, Michael Leone, Kiana Keller, John A. Branda, Judith Steen, Shibani S. Mukerji, Hanno Steen
Publikováno v:
Viruses, Vol 14, Iss 12, p 2757 (2022)
Herpesviruses have complex mechanisms enabling infection of the human CNS and evasion of the immune system, allowing for indefinite latency in the host. Herpesvirus infections can cause severe complications of the central nervous system (CNS). Here,
Externí odkaz:
https://doaj.org/article/9854b48c7f3d46579357a022b2699a6b
Publikováno v:
J Neurovirol
State-of-the-art liquid chromatography/mass spectrometry (LC/MS)-based proteomic technologies, using microliter amounts of patient plasma, can detect and quantify several hundred plasma proteins in a high throughput fashion, allowing for the discover
Autor:
Patrick van Zalm, Arthur Viodé, Kinga Smolen, Benoit Fatou, Arash Nemati Hayati, Christoph N. Schlaffner, Ofer Levy, Judith Steen, Hanno Steen
Publikováno v:
Journal of Proteome Research, 21(11), 2810-2814. American Chemical Society
Combining robust proteomics instrumentation with high-throughput enabling liquid chromatography (LC) systems (e.g., timsTOF Pro and the Evosep One system, respectively) enabled mapping the proteomes of 1000s of samples. Fragpipe is one of the few com
Autor:
Kathrin Wenger, Arthur Viode, Christoph N. Schlaffner, Patrick van Zalm, Long Cheng, Tammy Dellovade, Xavier Langlois, Anthony Bannon, Theresa R. Connors, Derek Oakley, Bernhard Renard, Juri Rappsilber, Bradley Hyman, Hanno Steen, Judith Steen
Background: Mouse models that overexpress human mutant Tau (P301S and P301L) are commonly used in preclinical studies of Alzheimer’s Disease (AD) and while several drugs showed therapeutic effects in these mice, they were ineffective in humans. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d04f2e6a95d01dc81b248d4187f4f39
https://doi.org/10.21203/rs.3.rs-2056948/v1
https://doi.org/10.21203/rs.3.rs-2056948/v1
Autor:
Joann Diray-Arce, Slim Fourati, Naresh Doni Jayavelu, Ravi Patel, Cole Maguire, Ana C. Chang, Ravi Dandekar, Jingjing Qi, Brian Lee, Patrick van Zalm, Andrew Schroeder, Ernie Chen, Anna Konstorum, Anderson Brito, Jeremy P. Gygi, Alvin Kho, Jing Chen, Shrikant Pawar, Ana Silvia Gonzalez-Reiche, Annmarie Hoch, Carly E. Milliren, James A. Overton, Kerstin Westendorf, Charles B. Cairns, Nadine Rouphael, Steven Bosinger, Seunghee Kim-Schulze, Florian Krammer, Lindsey Rosen, Nathan Grubaugh, Harm van Bakel, Michael Wilson, Jayant Rajan, Hanno Steen, Walter Eckalbar, Chris Cotsapas, Charles R. Langelier, Ofer Levy, Matthew C. Altman, Holden Maecker, Ruth R. Montgomery, Elias K. Haddad, Rafick P. Sekaly, Denise Esserman, Al Ozonoff, Patrice M. Becker, Alison D. Augustine, Leying Guan, Bjoern Peters, Steven H. Kleinstein
Publikováno v:
Cell Reports Medicine. :101079
Autor:
Saima Ahmed, Oludare A. Odumade, Patrick van Zalm, Kinga K. Smolen, Kimino Fujimura, Jan Muntel, Melissa S. Rotunno, Abigail B. Winston, Judith A. Steen, Richard B. Parad, Linda J. Van Marter, Stella Kourembanas, Hanno Steen
Publikováno v:
Neonatology
Introduction: Current techniques to diagnose and/or monitor critically ill neonates with bronchopulmonary dysplasia (BPD) require invasive sampling of body fluids, which is suboptimal in these frail neonates. We tested our hypothesis that it is feasi