Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Patrick Trojer"'
Autor:
Jonathan Wilson, Lei Cui, Costa Salojin, Anna Gardberg, Valerie Vivat, Jeffrey Lauer, Nico Cantone, Jacob Stuckey, Florence Poy, Ingrid Almeciga, Richard Cummings, Julian Levell, Jennifer Rocnik, Patrick Trojer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/2a8dd470c8804d72acb6de09b7967109
Autor:
Brian Egan, Chih-Chi Yuan, Madeleine Lisa Craske, Paul Labhart, Gulfem D Guler, David Arnott, Tobias M Maile, Jennifer Busby, Chisato Henry, Theresa K Kelly, Charles A Tindell, Suchit Jhunjhunwala, Feng Zhao, Charlie Hatton, Barbara M Bryant, Marie Classon, Patrick Trojer
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166438 (2016)
Chromatin immunoprecipitation and DNA sequencing (ChIP-seq) has been instrumental in inferring the roles of histone post-translational modifications in the regulation of transcription, chromatin compaction and other cellular processes that require mo
Externí odkaz:
https://doaj.org/article/626380f9c1534821baa58955f830b641
Autor:
James Smadbeck, Meghan B Peterson, Barry M Zee, Shivani Garapaty, Aashna Mago, Christina Lee, Athanassios Giannis, Patrick Trojer, Benjamin A Garcia, Christodoulos A Floudas
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90095 (2014)
Histones are small proteins critical to the efficient packaging of DNA in the nucleus. DNA-protein complexes, known as nucleosomes, are formed when the DNA winds itself around the surface of the histones. The methylation of histone residues by enhanc
Externí odkaz:
https://doaj.org/article/29537de5ebce4c40b98eda656f03eace
Autor:
Kristie A. Blum, Jeffrey G. Supko, Michael B. Maris, Ian W. Flinn, Andre Goy, Anas Younes, Suresh Bobba, Adrian M. Senderowicz, Sergey Efuni, Ronda Rippley, Gozde Colak, Patrick Trojer, Jeremy S. Abramson
Publikováno v:
Cancer Research Communications. 2:795-805
Purpose: NF-κB, a transcription factor essential for inflammatory responses, is constitutively activated in many lymphomas. In preclinical studies, pelabresib (CPI-0610), an investigational (BET) bromodomain inhibitor, downregulated NF-κB signaling
Autor:
Jeremy S. Abramson, Patrick Trojer, Gozde Colak, Ronda Rippley, Sergey Efuni, Adrian M. Senderowicz, Suresh Bobba, Anas Younes, Andre Goy, Ian W. Flinn, Michael B. Maris, Jeffrey G. Supko, Kristie A. Blum
Supplemental tables with the number of patients treated with number of cycles and the incidence of DLTs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3176bc8262bc52b8823efce4e47f6acd
https://doi.org/10.1158/2767-9764.22544999
https://doi.org/10.1158/2767-9764.22544999
Autor:
Jeremy S. Abramson, Patrick Trojer, Gozde Colak, Ronda Rippley, Sergey Efuni, Adrian M. Senderowicz, Suresh Bobba, Anas Younes, Andre Goy, Ian W. Flinn, Michael B. Maris, Jeffrey G. Supko, Kristie A. Blum
Purpose:NF-κB, a transcription factor essential for inflammatory responses, is constitutively activated in many lymphomas. In preclinical studies, pelabresib (CPI-0610), an investigational (BET) bromodomain inhibitor, downregulated NF-κB signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ca73113538578549d12f5fbd38f10c
https://doi.org/10.1158/2767-9764.c.6550823
https://doi.org/10.1158/2767-9764.c.6550823
Autor:
Jeremy S. Abramson, Patrick Trojer, Gozde Colak, Ronda Rippley, Sergey Efuni, Adrian M. Senderowicz, Suresh Bobba, Anas Younes, Andre Goy, Ian W. Flinn, Michael B. Maris, Jeffrey G. Supko, Kristie A. Blum
CONSORT diagram of patient disposition throughout study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e50340fb0c681ba5dcfe11908415005
https://doi.org/10.1158/2767-9764.22545008.v1
https://doi.org/10.1158/2767-9764.22545008.v1
Autor:
Stephen B. Baylin, Hariharan Easwaran, Marie Classon, Patrick Trojer, David Arnott, Tommy K. Cheung, Catherine Wilson, Ioannis Kagiampakis, Benjamin R. Leadem
Contains Tables S1 and S2. Supplementary Table 1: List of PCR primers. Supplementary Table 2: Sensitivity of Breast Cancer Cell Lines to CPI-455 Cell Viability was measured following exposure to CPI-455 for 8 days.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4e7fae45bdbac8c44974efd5328bfc
https://doi.org/10.1158/0008-5472.22411056
https://doi.org/10.1158/0008-5472.22411056
Autor:
Stephen B. Baylin, Hariharan Easwaran, Marie Classon, Patrick Trojer, David Arnott, Tommy K. Cheung, Catherine Wilson, Ioannis Kagiampakis, Benjamin R. Leadem
Effects of KDM5i and DAC on enhancers and de novo super-enhancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080240ddfe7230e203c294e19dd14b77
https://doi.org/10.1158/0008-5472.22411068.v1
https://doi.org/10.1158/0008-5472.22411068.v1
Autor:
Stephen B. Baylin, Hariharan Easwaran, Marie Classon, Patrick Trojer, David Arnott, Tommy K. Cheung, Catherine Wilson, Ioannis Kagiampakis, Benjamin R. Leadem
Legends for Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bb63882753e89ef59be8b901dab75a
https://doi.org/10.1158/0008-5472.22411059
https://doi.org/10.1158/0008-5472.22411059