Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Patrick T. Rudak"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100838- (2021)
Summary: Physical confinement, or restraint, is a psychological stressor used in rodent studies. A single restraint episode elevates blood corticosterone levels, a hallmark of stress responses. Repeated restraint results in habituation (or desensitiz
Externí odkaz:
https://doaj.org/article/4853bc926b6a4720b3a3d03cde4691c5
Autor:
Patrick T. Rudak, Joshua Choi, Katie M. Parkins, Kelly L. Summers, Dwayne N. Jackson, Paula J. Foster, Anton I. Skaro, Ken Leslie, Vivian C. McAlister, Vijay K. Kuchroo, Wataru Inoue, Olivier Lantz, S.M. Mansour Haeryfar
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108979- (2021)
Summary: The deleterious effects of psychological stress on mainstream T lymphocytes are well documented. However, how stress impacts innate-like T cells is unclear. We report that long-term stress surprisingly abrogates both T helper 1 (TH1)- and TH
Externí odkaz:
https://doaj.org/article/6b28ec3ee5014eb1b4081f330d2f952d
Autor:
Joshua Choi, Crystal L Schmerk, Tina S Mele, Patrick T Rudak, Christine M Wardell, Gansen Deng, Farzan R Pavri, Kyoungok Kim, Gediminas Cepinskas, Wenqing He, SM Mansour Haeryfar
Publikováno v:
Immunology & Cell Biology. 101:249-261
Sepsis-elicited immunosuppression elevates the risk of secondary infections. We used a clinically relevant mouse model and serial peripheral blood samples from patients to assess the antimicrobial activities of mucosa-associated invariant T (MAIT) ce
Autor:
Fatemeh Khadir, Christopher R Shaler, Ahmad Oryan, Patrick T Rudak, Delfina M Mazzuca, Tahereh Taheri, Jimmy D Dikeakos, S M Mansour Haeryfar, Sima Rafati
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 8, p e0006701 (2018)
Leishmaniasis is a serious global health problem affecting many people worldwide. While patients with leishmaniasis can be treated with several agents, drug toxicicty and the emergence of resistant strains render available treatments ineffective in t
Externí odkaz:
https://doaj.org/article/d7617d3c1b8a423690c9ad2aa72beeec
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2388
Invariant natural killer T (iNKT) cells are innate-like, lipid-reactive T lymphocytes known for their potent immunomodulatory properties. In addition to expressing and utilizing cytolytic effector molecules of their own against certain target cells,
Autor:
Wataru Inoue, S. M. Mansour Haeryfar, Kelly L. Summers, Dwayne N. Jackson, Amer M. Burhan, Joshua Choi, Patrick T. Rudak, Rakshith Gangireddy
Publikováno v:
Brain, Behavior, and Immunity. 80:793-804
Stress is known to impede certain host defense mechanisms, including those governed by conventional T lymphocytes. However, whether innate-like T lymphocytes, such as invariant natural killer T (iNKT) and mucosa-associated invariant T (MAIT) cells, a
Autor:
K. L. Summers, Ken Leslie, Anton I. Skaro, S. M. Mansour Haeryfar, Wataru Inoue, Vijay K. Kuchroo, Paula J. Foster, Joshua Choi, Olivier Lantz, Patrick T. Rudak, Vivian C. McAlister, Katie M. Parkins, Dwayne N. Jackson
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108979-(2021)
Cell reports
Cell reports
SUMMARY The deleterious effects of psychological stress on mainstream T lymphocytes are well documented. However, how stress impacts innate-like T cells is unclear. We report that long-term stress surprisingly abrogates both T helper 1 (TH1)- and TH2
Autor:
Tony, Yao, Patrick T, Rudak, Céline M, Laumont, Alex R, Michaud, Rasheduzzaman, Rashu, Natasha N, Knier, Paula J, Foster, Hamish E G, McWilliam, Jose A, Villadangos, Brad H, Nelson, Gabriel E, DiMattia, Trevor G, Shepherd, S M Mansour, Haeryfar
Publikováno v:
Cancer immunology, immunotherapy : CII. 71(5)
The low mutational burden of epithelial ovarian cancer (EOC) is an impediment to immunotherapies that rely on conventional MHC-restricted, neoantigen-reactive T lymphocytes. Mucosa-associated invariant T (MAIT) cells are MR1-restricted T cells with r
Publikováno v:
Methods in Molecular Biology ISBN: 9781071617748
Invariant natural killer T (iNKT) cells are innate-like, lipid-reactive T lymphocytes known for their potent immunomodulatory properties. In addition to expressing and utilizing cytolytic effector molecules of their own against certain target cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12bf86c057114fa3e4f7cd3d8138eb3b
https://doi.org/10.1007/978-1-0716-1775-5_15
https://doi.org/10.1007/978-1-0716-1775-5_15
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100838-(2021)
Summary Physical confinement, or restraint, is a psychological stressor used in rodent studies. A single restraint episode elevates blood corticosterone levels, a hallmark of stress responses. Repeated restraint results in habituation (or desensitiza