Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Patrick T. McGrath"'
Autor:
Zachary V. Johnson, Brianna E. Hegarty, George W. Gruenhagen, Tucker J. Lancaster, Patrick T. McGrath, Jeffrey T. Streelman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Social behaviors are diverse in nature, but it is unclear how conserved genes, brain regions, and cell populations generate this diversity. Here we investigate bower-building, a recently-evolved social behavior in cichlid fishes. We use sing
Externí odkaz:
https://doaj.org/article/8849c51131974a11bbb1ed7b4b4073d2
Autor:
Chinar Patil, Jonathan B. Sylvester, Kawther Abdilleh, Michael W. Norsworthy, Karen Pottin, Milan Malinsky, Ryan F. Bloomquist, Zachary V. Johnson, Patrick T. McGrath, Jeffrey T. Streelman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Lake Malawi cichlid fishes exhibit extensive divergence in form and function built from a relatively small number of genetic changes. We compared the genomes of rock- and sand-dwelling species and asked which genetic variants differed among
Externí odkaz:
https://doaj.org/article/46eae42d2f5b43029dbc177bba9c934c
Quantitative benzimidazole resistance and fitness effects of parasitic nematode beta-tubulin alleles
Autor:
Clayton M. Dilks, Steffen R. Hahnel, Qicong Sheng, Lijiang Long, Patrick T. McGrath, Erik C. Andersen
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss , Pp 28-36 (2020)
Infections by parasitic nematodes inflict a huge burden on the health of humans and livestock throughout the world. Anthelmintic drugs are the first line of defense against these infections. Unfortunately, resistance to these drugs is rampant and con
Externí odkaz:
https://doaj.org/article/8ba56406d5eb4071851347b0bb36e13a
Autor:
Zachary V. Johnson, Manu Tej Sharma Arrojwala, Vineeth Aljapur, Tyrone Lee, Tucker J. Lancaster, Mark C. Lowder, Karen Gu, Joseph I. Stockert, Rachel L. Lecesne, Jean M. Moorman, Jeffrey T. Streelman, Patrick T. McGrath
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract In the wild, behaviors are often expressed over long time periods in complex and dynamic environments, and many behaviors include direct interaction with the environment itself. However, measuring behavior in naturalistic settings is difficu
Externí odkaz:
https://doaj.org/article/48ac8af7396144dab905b7bd5ebb1129
Autor:
Lijiang Long, Zachary V. Johnson, Junyu Li, Tucker J. Lancaster, Vineeth Aljapur, Jeffrey T. Streelman, Patrick T. McGrath
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101591- (2020)
Summary: Many behaviors that are critical for survival and reproduction are expressed over extended time periods. The ability to inexpensively record and store large volumes of video data creates new opportunities to understand the biological basis o
Externí odkaz:
https://doaj.org/article/831cfc07c01946fcb632f4186bb108a2
Publikováno v:
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background The thousands of species of closely related cichlid fishes in the great lakes of East Africa are a powerful model for understanding speciation and the genetic basis of trait variation. Recently, the genomes of five species of Afri
Externí odkaz:
https://doaj.org/article/3a5da474f700437aa805b9ae088d68d8
Autor:
Kathryn S. Evans, Yuehui Zhao, Shannon C. Brady, Lijiang Long, Patrick T. McGrath, Erik C. Andersen
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 1, Pp 289-298 (2017)
Species inhabit a variety of environmental niches, and the adaptation to a particular niche is often controlled by genetic factors, including gene-by-environment interactions. The genes that vary in order to regulate the ability to colonize a niche a
Externí odkaz:
https://doaj.org/article/da3d26aef861447691736f4f703a62c9
Autor:
Adriana San-Miguel, Peri T. Kurshan, Matthew M. Crane, Yuehui Zhao, Patrick T. McGrath, Kang Shen, Hang Lu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Experimenter scoring of cellular imaging data can be biased. This study describes an automated and unbiased multidimensional phenotyping method that relies on machine learning and complex feature computation of imaging data, and identifies weak allel
Externí odkaz:
https://doaj.org/article/03b8216cade54677a546756f6c9445f4
Autor:
Zachary V. Johnson, Brianna E. Hegarty, George W. Gruenhagen, Tucker J. Lancaster, Patrick T. McGrath, Jeffrey T. Streelman
Social behaviors are essential for survival and reproduction and vary within and among species. We integrate single nucleus RNA-sequencing (snRNA-seq), comparative genomics, and automated behavior analysis to investigate a recently-evolved social “
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcf71c26f8b60ce2431f93c67e3b6484
https://doi.org/10.1101/2022.08.09.503380
https://doi.org/10.1101/2022.08.09.503380
Selfish genetic elements can promote their transmission at the expense of individual survival, creating conflict between the element and the rest of the genome. Recently, a large number of toxin-antidote (TA) post-segregation distorters have been ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09473dff4a2bf85dbd29edce163c47a0
https://doi.org/10.1101/2022.07.15.500229
https://doi.org/10.1101/2022.07.15.500229