Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Patrick T. Colahan"'
Autor:
Andrew D. Smith, Steven C. Ghivizzani, Anthony Dacanay, Patrick T. Colahan, Padraic P. Levings, Rachael S. Watson Levings, Glyn D. Palmer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe54e78aa702d00262fbdcad349192c
http://www.intechopen.com/articles/show/title/gene-therapy-for-the-treatment-of-equine-osteoarthritis
http://www.intechopen.com/articles/show/title/gene-therapy-for-the-treatment-of-equine-osteoarthritis
Autor:
Steven C. Ghivizzani, Margaret E. White, Eric P. Gibbs, Alison J. Morton, E. Viktoria Hyddmark, Mathew Winter, Michael J. Dark, David A. Myara, Yuan Lu, Christopher H. Evans, E. Anthony Dacanay, David M. Nickerson, Gregory B. Foremny, Patrick T. Colahan, Rice B, Elham Nasri, Ted A. Broome, Rachael S. Watson Levings, Ali Zarezadeh, Andrew D. Smith, Padraic P. Levings
Publikováno v:
Human Gene Therapy Clinical Development. 29:101-112
The authors are investigating self-complementary adeno-associated virus (scAAV) as a vector for intra-articular gene-delivery of interleukin-1 receptor antagonist (IL-1Ra), and its therapeutic capacity in the treatment of osteoarthritis (OA). To mode
Autor:
Matthew D. Winter, Alison J. Morton, Patrick T. Colahan, Jorge A. Hernandez, S.C. Ghivizzani, Murray P. Brown, Andrew D. Smith, David M. Nickerson
Publikováno v:
Veterinary Radiology & Ultrasound. 57:502-514
Magnetic resonance imaging (MRI) is the most sensitive imaging modality to detect the early changes of osteoarthritis. Currently, there is no quantifiable method to tract these pathological changes over time in the horse. The objective of this experi
Autor:
Margaret E. White, Michael J. Dark, Elham Nasri, E. Anthony Dacanay, David A. Myara, E. Viktoria Hyddmark, Padraic P. Levings, Rice B, Gregory B. Foremny, Ali Zarezadeh, Ted A. Broome, Christopher H. Evans, Steven C. Ghivizzani, Rachael S. Watson Levings, Yuan Lu, David M. Nickerson, Eric P. Gibbs, Andrew D. Smith, Patrick T. Colahan, Alison J. Morton, Mathew Winter
Toward the treatment of osteoarthritis (OA), the authors have been investigating self-complementary adeno-associated virus (scAAV) for intra-articular delivery of therapeutic gene products. As OA frequently affects weight-bearing joints, pharmacokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2da6ab491ca06acafb1c2a6279650d2
https://europepmc.org/articles/PMC6007808/
https://europepmc.org/articles/PMC6007808/
Autor:
Saundra H. Tenbroeck, Monika W. Oli, Megan J. Davidson, Patrick T. Colahan, Benjamin I. Davids
Publikováno v:
Veterinary Surgery. 44:648-652
Objective To compare the efficacy of sterile preoperative skin antisepsis using either a 5-minute mechanical preparation or 5-minute non-mechanical preparation with chlorhexidine gluconate 4% solution. Study Design Matched design, ANOVA. Animals Heal
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 37:260-268
The disposition of plasma glycopyrrolate (GLY) is characterized by a three-compartment pharmacokinetic model after a 1-mg bolus intravenous dose to Standardbred horses. The median (range) plasma clearance (Clp), volume of distribution of the central
Autor:
Dacanay Ea, Elvire Gouze, Ted A. Broome, Michael J. Dark, William W. Hauswirth, Jesse D Kay, Patrick T. Colahan, Jean Noel Gouze, David M. Nickerson, Padraic P. Levings, Andrew D. Smith, Rice B, Rachael S Watson, Steven C. Ghivizzani
Publikováno v:
Gene therapy
With the long-term goal of developing a gene-based treatment for osteoarthritis (OA), we performed studies to evaluate the equine joint as a model for adeno-associated virus (AAV)-mediated gene transfer to large, weight-bearing human joints. A self-c
Publikováno v:
Oxidative Stress and Antioxidant Protection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeb088a1e0e1beacca7113e9ce726b30
https://doi.org/10.1002/9781118832431.ch13
https://doi.org/10.1002/9781118832431.ch13
Autor:
Raymond C. Boston, Cornelius E. Uboh, Mary A. Robinson, Lawrence R. Soma, Y. Liu, Patrick T. Colahan, Xiaoqing Li
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 36:181-191
This study investigated and compared the pharmacokinetics of intra-articular (IA) administration of dexamethasone sodium phosphate (DSP) into three equine joints, femoropatellar (IAS), radiocarpal (IAC), and metacarpophalangeal (IAF), and the intramu
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 34:605-608
Glycopyrrolate, designated a class 3 substance by the Associa-tion of Racing Commissioners International, Inc., is regulated inracing horses because of its potential to affect performance.Although it has veterinary clinical applications by inhibiting