Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Patrick T McGann"'
Autor:
Leon Tshilolo, Baba Inusa, Kwaku Ohene-Frempong, Jonathan Spector, Julie Makani, Siana Nkya, Natalie Henrich, Natasha M Archer, Venee N Tubman, Patrick T McGann, Emmanuela Eusebio Ambrose
Publikováno v:
BMJ Open, Vol 12, Iss 3 (2022)
Objectives Given the fundamental role of newborn bloodspot screening (NBS) to enable prompt diagnosis and optimal clinical management of individuals with sickle cell disease (SCD), we sought to systematically assess enablers and barriers to implement
Externí odkaz:
https://doaj.org/article/b2f0d8b1d15f4f8fb4f2c5133533fcdc
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Enhanced levels of resistance to antibiotics arising from amplification of an antibiotic resistance gene that impact therapeutic options are increasingly observed. Amplification can also disclose novel phenotypes leading to treatment failure
Externí odkaz:
https://doaj.org/article/a9d660f9818046d799659642b28686ab
Autor:
Emily R. Meier, Susan E. Creary, Matthew M. Heeney, Min Dong, Abena O. Appiah-Kubi, Stephen C. Nelson, Omar Niss, Connie Piccone, Maa-Ohui Quarmyne, Charles T. Quinn, Kay L. Saving, John P. Scott, Ravi Talati, Teresa S. Latham, Amanda Pfeiffer, Lisa M. Shook, Alexander A. Vinks, Adam Lane, Patrick T. McGann
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Sickle cell disease (SCD) is a severe and devastating hematological disorder that affects over 100,000 persons in the USA and millions worldwide. Hydroxyurea is the primary disease-modifying therapy for the SCD, with proven benefi
Externí odkaz:
https://doaj.org/article/f4848c1e5cb84d1ca9d6331a034404f0
Autor:
Andrey A. Filippov, Wanwen Su, Kirill V. Sergueev, Richard T. Kevorkian, Erik C. Snesrud, Apichai Srijan, Yunxiu He, Derrick E. Fouts, Woradee Lurchachaiwong, Patrick T. McGann, Damon W. Ellison, Brett E. Swierczewski, Mikeljon P. Nikolich
Publikováno v:
Antibiotics, Vol 11, Iss 11, p 1659 (2022)
Shigellosis is a leading global cause of diarrheal disease and travelers’ diarrhea now being complicated by the dissemination of antibiotic resistance, necessitating the development of alternative antibacterials such as therapeutic bacteriophages (
Externí odkaz:
https://doaj.org/article/271f48e9383240e28dc902883835d77e
Autor:
Daniel Dexter, Patrick T. McGann
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 43:430-441
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c18c1e9738fa25f1cdbf1649b51ea090
https://doi.org/10.1002/phar.2792
https://doi.org/10.1002/phar.2792
Autor:
Alina Sadaf, Katie G. Seu, Elizabeth Thaman, Rose Fessler, Diamantis G. Konstantinidis, Holly A. Bonar, Jennifer Korpik, Russell E. Ware, Patrick T. McGann, Charles T. Quinn, Theodosia A. Kalfa
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Sickle cell anemia (SCA) is a hereditary hemoglobinopathy with a variable phenotype. There is no single biomarker that adequately predicts disease severity and can be used to monitor treatment response in patients in clinical trials and clinical care
Externí odkaz:
https://doaj.org/article/b9b6c29ecdaf45248ce52b9860c4b661
Autor:
Jaime L. Mencke, Yunxiu He, Andrey A. Filippov, Mikeljon P. Nikolich, Ashton T. Belew, Derrick E. Fouts, Patrick T. McGann, Brett E. Swierczewski, Derese Getnet, Damon W. Ellison, Katie R. Margulieux
Publikováno v:
Viruses, Vol 14, Iss 4, p 708 (2022)
Providencia rettgeri is an emerging opportunistic Gram-negative pathogen with reports of increasing antibiotic resistance. Pan-drug resistant (PDR) P. rettgeri infections are a growing concern, demonstrating a need for the development of alternative
Externí odkaz:
https://doaj.org/article/fbbd716d5a3947f0824bbdd660dc263b
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1851-1855
Objectives To examine the causes of antibiotic resistance in the extensively resistant global clone 1 (GC1) Acinetobacter baumannii isolate MRSN 56 recovered at a US military treatment facility. Methods MRSN 56 was sequenced using MinION (Oxford Nano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd9e2702c0daab3defd7dafb05c9977
https://doi.org/10.1093/jac/dkac115
https://doi.org/10.1093/jac/dkac115
Publikováno v:
Microbiology Spectrum. 10
Heteroresistance, a significant issue that is known to impact antibiotic treatment outcomes, is caused by the presence of spontaneously arising cells with elevated levels of resistance to therapeutically important antibiotics in a population of susce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c1d692b680bcfd68a060aaff40a4d8c
https://doi.org/10.1128/spectrum.02287-22
https://doi.org/10.1128/spectrum.02287-22
Autor:
Ting L. Luo, Brendan W. Corey, Erik Snesrud, Alina Iovleva, Christi L. McElheny, Lan N. Preston, Yoon I. Kwak, Jason W. Bennett, Yohei Doi, Patrick T. McGann, Francois Lebreton
Publikováno v:
Microbial Genomics. 8
Carbapenem-resistant Enterobacterales pose an urgent threat to human health worldwide. Klebsiella pneumoniae sequence type (ST) 14, initially identified in the Middle East and South-Asia and co-harbouring the carbapenemase genes bla OXA-232 and bla N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6682f2da38e2149fa9b6edbf516c8e8
https://doi.org/10.1099/mgen.0.000892
https://doi.org/10.1099/mgen.0.000892