Výsledky vyhledávání - "Patrick Stern"

Akademický článek

Assessing automated air-taxis for urban mobility

Autor: Bin Hu, Georg Brandstätter, Johannes Müller, Patrick Stern, Alexander Schaffenberger, Arno Fallast, Samuel Lesak, Dieter Meinhard

Publikováno v: European Transport Research Review, Vol 16, Iss 1, Pp 1-8 (2024)

Abstract This paper explores the feasibility and potential implications of automated air-taxis as a new mode of urban transport. By applying flight simulation and operations research, we investigate different questions regarding travel time, travel c

Externí odkaz: https://doaj.org/article/678721f6c0bf4d7d866f20aae4cf4052

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Akademický článek

Colesevelam Reduces Ethanol-Induced Liver Steatosis in Humanized Gnotobiotic Mice

Autor: Noemí Cabré, Yi Duan, Cristina Llorente, Mary Conrad, Patrick Stern, Dennis Yamashita, Bernd Schnabl

Publikováno v: Cells, Vol 10, Iss 6, p 1496 (2021)

Alcohol-related liver disease is associated with intestinal dysbiosis. Functional changes in the microbiota affect bile acid metabolism and result in elevated serum bile acids in patients with alcohol-related liver disease. The aim of this study was

Externí odkaz: https://doaj.org/article/bf125008c22043ba918a9b5e8421a7c1

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Akademický článek

Lentiviral-based approach for the validation of cancer therapeutic targets in vivo

Autor: Chiara Ambrogio, Patrick Stern, Claudio Scuoppo, Harald Kranz, Mariano Barbacid, David Santamaría

Publikováno v: BioTechniques, Vol 57, Iss 4, Pp 179-187 (2014)

Despite the pressing need for novel cancer treatments, our improved understanding of tumor biology is not being successfully translated into better therapies. Here we present a lentiviral vector that enables in vivo validation of cancer therapeutic t

Externí odkaz: https://doaj.org/article/19972bc6aa174747995a49196454c916

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Akademický článek

Expression of multiple artificial microRNAs from a chicken miRNA126-based lentiviral vector.

Autor: Steve C-Y Chen, Patrick Stern, Zhuyan Guo, Jianzhu Chen

Publikováno v: PLoS ONE, Vol 6, Iss 7, p e22437 (2011)

BackgroundThe use of RNAi in both basic and translational research often requires expression of multiple siRNAs from the same vector.Methods/principal findingsWe have developed a novel chicken miR126-based artificial miRNA expression system that can

Externí odkaz: https://doaj.org/article/bd9302d4eb3c44a78ba84adf7a318e03

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Akademický článek

Informational lesions: optical perturbation of spike timing and neural synchrony via microbial opsin gene fusions

Autor: Xue Han, Xiaofeng Qian, Patrick Stern, Amy Chuong, Edward S Boyden

Publikováno v: Frontiers in Molecular Neuroscience, Vol 2 (2009)

Synchronous neural activity occurs throughout the brain in association with normal and pathological brain functions. Despite theoretical work exploring how such neural coordination might facilitate neural computation and be corrupted in disease state

Externí odkaz: https://doaj.org/article/98a936485810487dad89665657508ec5

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Colesevelam ameliorates non-alcoholic steatohepatitis and obesity in mice

Autor: Phillipp Hartmann, Yi Duan, Yukiko Miyamoto, Münevver Demir, Sonja Lang, Elda Hasa, Patrick Stern, Dennis Yamashita, Mary Conrad, Lars Eckmann, Bernd Schnabl

Publikováno v: Hepatology international, vol 16, iss 2

Background Obesity, non-alcoholic fatty liver disease (NAFLD) and its more advanced form non-alcoholic steatohepatitis (NASH) are important causes of morbidity and mortality worldwide. Bile acid dysregulation is a pivotal part in their pathogenesis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d25e8f54e57658a39ecc59185b82c40
https://doi.org/10.1007/s12072-022-10296-w

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