Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Patrick Smadbeck"'
Autor:
Maria C. Costanzo, Marcin von Grotthuss, Jeffrey Massung, Dongkeun Jang, Lizz Caulkins, Ryan Koesterer, Clint Gilbert, Ryan P. Welch, Parul Kudtarkar, Quy Hoang, Andrew P. Boughton, Preeti Singh, Ying Sun, Marc Duby, Annie Moriondo, Trang Nguyen, Patrick Smadbeck, Benjamin R. Alexander, MacKenzie Brandes, Mary Carmichael, Peter Dornbos, Todd Green, Kenneth C. Huellas-Bruskiewicz, Yue Ji, Alexandria Kluge, Aoife C. McMahon, Josep M. Mercader, Oliver Ruebenacker, Sebanti Sengupta, Dylan Spalding, Daniel Taliun, Philip Smith, Melissa K. Thomas, Beena Akolkar, M. Julia Brosnan, Andriy Cherkas, Audrey Y. Chu, Eric B. Fauman, Caroline S. Fox, Tania Nayak Kamphaus, Melissa R. Miller, Lynette Nguyen, Afshin Parsa, Dermot F. Reilly, Hartmut Ruetten, David Wholley, Norann A. Zaghloul, Gonçalo R. Abecasis, David Altshuler, Thomas M. Keane, Mark I. McCarthy, Kyle J. Gaulton, Jose C. Florez, Michael Boehnke, Noël P. Burtt, Jason Flannick, Gonçalo Abecasis, Nicholette D. Allred, Jennifer E. Below, Richard Bergman, Joline W.J. Beulens, John Blangero, Krister Bokvist, Erwin Bottinger, Donald Bowden, Christopher Brown, Kenneth Bruskiewicz, Inês Cebola, John Chambers, Yii-Der Ida Chen, Christopher Clark, Melina Claussnitzer, Nancy J. Cox, Marcel den Hoed, Duc Dong, Ravindranath Duggirala, Josée Dupuis, Petra J.M. Elders, Jesse M. Engreitz, Eric Fauman, Jorge Ferrer, Paul Flicek, Matthew Flickinger, Timothy M. Frayling, Kelly A. Frazer, Anna L. Gloyn, Craig L. Hanis, Robert Hanson, Andrew T. Hattersley, Hae Kyung Im, Sidra Iqbal, Suzanne B.R. Jacobs, Dong-Keun Jang, Tad Jordan, Tania Kamphaus, Fredrik Karpe, Seung K. Kim, Kasper Lage, Leslie A. Lange, Mitchell Lazar, Donna Lehman, Ching-Ti Liu, Ruth J.F. Loos, Ronald Ching-wan Ma, Patrick MacDonald, Matthew T. Maurano, Gil McVean, James B. Meigs, Braxton Mitchell, Karen L. Mohlke, Samuel Morabito, Claire Morgan, Shannon Mullican, Sharvari Narendra, Maggie C.Y. Ng, Colin N.A. Palmer, Stephen C.J. Parker, Antonio Parrado, Aaron C. Pawlyk, Ewan R. Pearson, Andrew Plump, Michael Province, Thomas Quertermous, Susan Redline, Bing Ren, Stephen S. Rich, J. Brent Richards, Jerome I. Rotter, Rany M. Salem, Maike Sander, Michael Sanders, Dharambir Sanghera, Laura J. Scott, David Siedzik, Xueling Sim, Robert Sladek, Kerrin Small, Peter Stein, Heather M. Stringham, Katalin Susztak, Leen M. ’t Hart, Kent Taylor, Jennifer A. Todd, Miriam S. Udler, Benjamin Voight, Andre Wan, Kaan Yuksel
Publikováno v:
710.e6
AMP-T2D Consortium 2023, ' The Type 2 Diabetes Knowledge Portal : An open access genetic resource dedicated to type 2 diabetes and related traits ', Cell Metabolism, vol. 35, no. 4, pp. 695-710.e6 . https://doi.org/10.1016/j.cmet.2023.03.001
Cell Metab
Cell metabolism, vol 35, iss 4
Cell Metabolism, 35(4), 695-710.e6. Cell Press
AMP-T2D Consortium 2023, ' The Type 2 Diabetes Knowledge Portal : An open access genetic resource dedicated to type 2 diabetes and related traits ', Cell Metabolism, vol. 35, no. 4, pp. 695-710.e6 . https://doi.org/10.1016/j.cmet.2023.03.001
Cell Metab
Cell metabolism, vol 35, iss 4
Cell Metabolism, 35(4), 695-710.e6. Cell Press
Associations between human genetic variation and clinical phenotypes have become a foundation of biomedical research. Most repositories of these data seek to be disease-agnostic and therefore lack disease-focused views. The Type 2 Diabetes Knowledge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04094df70ceb068c99b961c7447fbab0
http://hdl.handle.net/10044/1/104941
http://hdl.handle.net/10044/1/104941
Autor:
Yiannis N. Kaznessis, Patrick Smadbeck
Publikováno v:
Current Opinion in Chemical Engineering. 5:90-95
Stochasticity in the dynamics of small reacting systems requires discrete-probabilistic models of reaction kinetics instead of traditional continuous-deterministic ones. The master probability equation is a complete model of randomly evolving molecul
Autor:
Patrick Smadbeck, Yiannis N. Kaznessis
Publikováno v:
Methods in Molecular Biology ISBN: 9781493918775
With inexpensive DNA synthesis technologies, we can now construct biological systems by quickly piecing together DNA sequences. Synthetic biology is the promising discipline that focuses on the construction of these new biological systems. Synthetic
Autor:
Yiannis N. Kaznessis, Patrick Smadbeck
Probability reigns in biology, with random molecular events dictating the fate of individual organisms, and propelling populations of species through evolution. In principle, the master probability equation provides the most complete model of probabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4268c84669b644a5307085121ed514
https://europepmc.org/articles/PMC3761596/
https://europepmc.org/articles/PMC3761596/
We discuss the importance of mathematical modeling in synthetic biology. We present the essential elements of the Synthetic Biology Software Suite (SynBioSS) and discuss the experimental construction and testing of two synthetic biological devices as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebce37636fb4b8f09f8edb4e92ee5ac4
https://doi.org/10.1016/b978-0-12-394430-6.00007-8
https://doi.org/10.1016/b978-0-12-394430-6.00007-8
Autor:
Adam P. Arkin, David Baker, Konstantinos Biliouris, Gregory Bokinsky, Bradley C. Bundy, Paolo Carrara, George M. Church, Patrick C. Cirino, Ryan E. Cobb, Dawn T. Eriksen, Todd Freestone, Martin Fussenegger, Dan Groff, Joao C. Guimaraes, Boon Chin Heng, Sui Huang, Mitsuhiro Itaya, Michael C. Jewett, Yiannis Kaznessis, Jay Keasling, Jin Eyun Kim, Tae Yong Kim, Yu Bin Kim, Yutetsu Kuruma, Sang Yup Lee, Sijin Li, Chang C. Liu, Pier Luigi Luisi, Yunzi Luo, Siying Ma, Michael T. Mee, Tereza Pereira de Souza, Shuai Qian, Arnaz Ranji, Florian Richter, Claudia Schmidt-Dannert, Jae Ho Shin, Patrick Smadbeck, Robert P. Smith, Seung Bum Sohn, Pasquale Stano, Nicholas Tang, Yu Tanouchi, Jingdong Tian, Ilya Tikh, Katherine Volzing, Harris H. Wang, Jeffrey C. Wu, Lingchong You, Huimin Zhao, Joseph Xu Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aae57baaa95a7defadc7cd4684612172
https://doi.org/10.1016/b978-0-12-394430-6.00022-4
https://doi.org/10.1016/b978-0-12-394430-6.00022-4
Autor:
Patrick Smadbeck, Yiannis N. Kaznessis
Publikováno v:
The Journal of chemical physics. 137(23)
In the present work, we address a major challenge facing the modeling of biochemical reaction networks: when using stochastic simulations, the computational load and number of unknown parameters may dramatically increase with system size and complexi
Autor:
Yiannis N. Kaznessis, Patrick Smadbeck
Publikováno v:
Chemical engineering science. 84
As stochastic simulations become increasingly common in biological research, tools for analysis of such systems are in demand. The deterministic analogue to stochastic models, a set of probability moment equations equivalent to the Chemical Master Eq
Autor:
Patrick Smadbeck, Michael P. H. Stumpf
Publikováno v:
Journal of the Royal Society Interface
Development is a process that needs to tightly coordinated in both space and time. Cell tracking and lineage tracing have become important experimental techniques in developmental biology and allow us to map the fate of cells and their progeny in bot
Autor:
Yiannis N. Kaznessis, Patrick Smadbeck
Publikováno v:
The Journal of Chemical Physics. 142:184101
We present elements of a stability theory for small, stochastic, nonlinear chemical reaction networks. Steady state probability distributions are computed with zero-information (ZI) closure, a closure algorithm that solves chemical master equations o