Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Patrick S. Page-McCaw"'
Autor:
Pavlo Khodakivskyi, Kevin P. Francis, Elena A. Dubikovskaya, Alexander D. Klose, Neal Paragas, Patrick S. Page-McCaw, Jason Paragas, Akio Kobayashi, Tomoaki Miyazaki, Jonathan Barasch, Katherine Xu, Sina A. Gharib, Yun-Wei A Hsu
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-12 (2019)
Communications Biology
Communications Biology
The kidney’s inherent complexity has made identifying cell-specific pathways challenging, particularly when temporally associating them with the dynamic pathophysiology of acute kidney injury (AKI). Here, we combine renal cell-specific luciferase r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949f21ecb58946df6b890fb475b7a3e9
http://link.springer.com/article/10.1038/s42003-019-0571-7
http://link.springer.com/article/10.1038/s42003-019-0571-7
Autor:
Amrutha Bagivalu Lakshminarasimha, Maximilian Michel, Patrick S. Page-McCaw, Diana Möckel, Felix Gremse
Publikováno v:
The Journal of endocrinology. 251(1)
The leptin system plays a crucial role in the regulation of appetite and energy homeostasis in vertebrates. While the phenotype of morbid obesity due to leptin (Lep) or leptin receptor (LEPR) loss of function is well established in mammals, evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff67ef121dd475d75476c15e9be1217
https://pubmed.ncbi.nlm.nih.gov/34265742
https://pubmed.ncbi.nlm.nih.gov/34265742
Autor:
Akira Muto, Michael B Orger, Ann M Wehman, Matthew C Smear, Jeremy N Kay, Patrick S Page-McCaw, Ethan Gahtan, Tong Xiao, Linda M Nevin, Nathan J Gosse, Wendy Staub, Karin Finger-Baier, Herwig Baier
Publikováno v:
PLoS Genetics, Vol 1, Iss 5, p e66 (2005)
The visual system converts the distribution and wavelengths of photons entering the eye into patterns of neuronal activity, which then drive motor and endocrine behavioral responses. The gene products important for visual processing by a living and b
Externí odkaz:
https://doaj.org/article/b1ce075af6c541f6a72f213770d1ce84
Publikováno v:
Proceedings of the National Academy of Sciences. 113:3084-3089
Leptin is the primary adipostatic factor in mammals. Produced largely by adipocytes in proportion to total adipose mass, the hormone informs the brain regarding total energy stored as triglycerides in fat cells. The hormone acts on multiple circuits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27dcfdb3e0227bbce5a90e3d6ab57968
https://doi.org/10.1073/pnas.1513212113
https://doi.org/10.1073/pnas.1513212113
Autor:
Wenbiao Chen, Ahmed Elaswad, Maximilian Michel, Roger D. Cone, Karim Khalil, Patrick S. Page-McCaw, Rex A. Dunham, David Cline
Publikováno v:
Journal of Visualized Experiments.
The complete genome of the channel catfish, Ictalurus punctatus, has been sequenced, leading to greater opportunities for studying channel catfish gene function. Gene knockout has been used to study these gene functions in vivo. The clustered regular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b55ca435742c3753dc1d60912c7f9e
https://doi.org/10.3791/56275
https://doi.org/10.3791/56275
Publikováno v:
Antioxidantsredox signaling. 27(12)
Basement membranes (BMs) are sheet-like structures of specialized extracellular matrix that underlie nearly all tissue cell layers including epithelial, endothelial, and muscle cells. BMs not only provide structural support but are also critical for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb3992b1c296319b7297e311c5de7a9
https://pubmed.ncbi.nlm.nih.gov/28657332
https://pubmed.ncbi.nlm.nih.gov/28657332
Publikováno v:
Scientific Reports
Matrix metalloproteinases (MMPs) are extracellular proteases that can cleave extracellular matrix and alter signaling pathways. They have been implicated in many disease states, but it has been difficult to understand the contribution of individual M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3757b17317e756878607999fae2adb1c
https://doi.org/10.1038/srep44560
https://doi.org/10.1038/srep44560
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 306:E799-E807
Insulin from islet β-cells maintains glucose homeostasis by stimulating peripheral tissues to remove glucose from circulation. Persistent elevation of insulin demand increases β-cell number through self-replication or differentiation (neogenesis) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff125afdceef467bd79304a17d03c641
https://doi.org/10.1152/ajpendo.00686.2013
https://doi.org/10.1152/ajpendo.00686.2013
Publikováno v:
Trends in genetics : TIG. 32(12)
Geneticists have long sought the ability to manipulate vertebrate genomes by directly altering the information encoded in specific genes. The recently discovered clustered regularly interspaced short palindromic repeats (CRISPR)–Cas9 endonuclease h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab9c21160d501546608e8ce5043c78e
https://pubmed.ncbi.nlm.nih.gov/27836208
https://pubmed.ncbi.nlm.nih.gov/27836208
Autor:
Aaron C. Raymond, Patrick S. Page-McCaw, LaChelle Blunt, Shaina Feldman, Carlton Hoyt, Kara D. Mann
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 298:R1288-R1297
Central regulation of cardiac output via the sympathetic and parasympathetic branches of the autonomic nervous system allows the organism to respond to environmental changes. Sudden onset stimuli, startle stimuli, are useful probes to study central r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8695b2937a94586449fcca8ef3c60379
https://doi.org/10.1152/ajpregu.00302.2009
https://doi.org/10.1152/ajpregu.00302.2009