Výsledky vyhledávání - "Patrick S Parfrey"

Akademický článek

XRCC3 Thr241Met and TYMS variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer.

Autor: Yanjing He, Michelle E Penney, Amit A Negandhi, Patrick S Parfrey, Sevtap Savas, Yildiz E Yilmaz

Publikováno v: PLoS ONE, Vol 13, Iss 2, p e0192316 (2018)

Metastasis is a major cause of mortality in cancer. Identifying prognostic factors that distinguish patients who will experience metastasis in the short-term and those that will be free of metastasis in the long-term is of particular interest in curr

Externí odkaz: https://doaj.org/article/3693798d5e8a4d87af325cfe44d1effd

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Akademický článek

Cardiac Biomarkers and Health-Related Quality of Life in New Hemodialysis Patients without Symptomatic Cardiac Disease

Autor: Christopher E Williams, Bryan M Curtis, Edward W Randell, Robert N Foley, Patrick S Parfrey

Publikováno v: Canadian Journal of Kidney Health and Disease, Vol 1 (2014)

Background: Health Related Quality of Life (HRQOL) is impaired in hemodialysis patients and cardiac biomarkers are elevated, but their relationship is uncertain. Objectives: To determine whether the cardiac biomarkers, troponin T and N terminal pro-B

Externí odkaz: https://doaj.org/article/2a5ce3921f1749c8a24b2ad3020cc1a0

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Akademický článek

Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.

Publikováno v: PLoS ONE, Vol 5, Iss 10, p e13314 (2010)

We previously identified an association between a mismatch repair gene, MLH1, promoter SNP (rs1800734) and microsatellite unstable (MSI-H) colorectal cancers (CRCs) in two samples. The current study expanded on this finding as we explored the genetic

Externí odkaz: https://doaj.org/article/45b1bc6790fc4e3ba3677cd88b67c739

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Akademický článek

Associations between polymorphisms in leptin and leptin receptor genes and colorectal cancer survival

Autor: Meizhi Du, Yu Wang, Jillian Vallis, Matin Shariati, Patrick S. Parfrey, John R. Mclaughlin, Peizhong Peter Wang, Yun Zhu

Publikováno v: Cancer Biology & Medicine, Vol 20, Iss 6, Pp 438-451 (2023)

Objective: Leptin (LEP) is an obesity-associated adipokine associated with tumor cell growth. We examined the relevance of genetic variants of LEP and leptin receptor (LEPR) to colorectal cancer (CRC) survival by using data from the Newfoundland Fami

Externí odkaz: https://doaj.org/article/41ab7b80abac4cc5a397dfb501a92abe

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Akademický článek

The Roles of MTRR and MTHFR Gene Polymorphisms in Colorectal Cancer Survival

Autor: Yu Wang, Meizhi Du, Jillian Vallis, Matin Shariati, Patrick S. Parfrey, John R. Mclaughlin, Peizhong Peter Wang, Yun Zhu

Publikováno v: Nutrients, Vol 14, Iss 21, p 4594 (2022)

Background: Paradoxically epidemiological data illustrate a negative relationship between dietary folate intake and colorectal cancer (CRC) risk. The occurrence and progression of CRC may be influenced by variants in some key enzyme coding genes in t

Externí odkaz: https://doaj.org/article/ed6f5217afc34c1e8fbcde467a1a3b95

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