Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Patrick R. Walsh"'
Publikováno v:
Endoscopy International Open, Vol 09, Iss 10, Pp E1549-E1555 (2021)
Background and study aims Gastroesophageal reflux disease (GERD) is common, especially in patients after gastric surgery. Medical management of GERD is ineffective in up to 30 % patients and revisional gastric surgery for management of GERD is associ
Externí odkaz:
https://doaj.org/article/3f1bbe24ec5a485a9e7a5c32f5f108a2
Autor:
Edwin K. S. Wong, Thomas M. Hallam, Vicky Brocklebank, Patrick R. Walsh, Kate Smith-Jackson, Victoria G. Shuttleworth, Thomas E. Cox, Holly E. Anderson, Paul Nigel Barlow, Kevin James Marchbank, Claire L. Harris, David Kavanagh
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Membranoproliferative glomerulonephritis (MPGN), C3 glomerulopathy (C3G), atypical haemolytic uraemic syndrome (aHUS) and age-related macular degeneration (AMD) have all been strongly linked with dysfunction of the alternative pathway (AP) of complem
Externí odkaz:
https://doaj.org/article/c7695199346d42058bf9585aa44c68ab
Autor:
Giuseppina Arbore, Erin E. West, Jubayer Rahman, Gaelle Le Friec, Nathalie Niyonzima, Mehdi Pirooznia, Ilker Tunc, Polychronis Pavlidis, Nicholas Powell, Yuesheng Li, Poching Liu, Aude Servais, Lionel Couzi, Veronique Fremeaux-Bacchi, Leo Placais, Alastair Ferraro, Patrick R. Walsh, David Kavanagh, Behdad Afzali, Paul Lavender, Helen J. Lachmann, Claudia Kemper
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Complement, while serving to remove pathogens in the circulation, is also important for synergizing with inflammasomes to modulate CD4 T cell activation. Here the authors show that CD46, a complement receptor expressed only in humans, is essential fo
Externí odkaz:
https://doaj.org/article/12d27a6322604934916857f1fe60bd7c
Autor:
Emily K, Glover, Kate, Smith-Jackson, Vicky, Brocklebank, Valerie, Wilson, Patrick R, Walsh, Emma K, Montgomery, Edwin K S, Wong, Sally, Johnson, Michal, Malina, David, Kavanagh, Neil S, Sheerin, Imran, Saif
Publikováno v:
Transplantation.
Atypical hemolytic uremic syndrome (aHUS) is a rare cause of end-stage kidney disease and associated with poor outcomes after kidney transplantation from early disease recurrence. Prophylactic eculizumab treatment at the time of transplantation is us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a100fa2f5e945b0c1bdf648ca30216
https://pubmed.ncbi.nlm.nih.gov/36413152
https://pubmed.ncbi.nlm.nih.gov/36413152
Autor:
Nikolai Tschernoster, Florian Erger, Patrick R. Walsh, Bairbre McNicholas, Margareta Fistrek, Sandra Habbig, Anna-Lena Schumacher, Kat Folz-Donahue, Christian Kukat, Mohammad R. Toliat, Christian Becker, Holger Thiele, David Kavanagh, Peter Nürnberg, Bodo B. Beck, Janine Altmüller
Complement factor H (CFH) and its related proteins have an essential role in regulating the alternative pathway of the complement system. Mutations and structural variants (SVs) of the CFH gene cluster, consisting of CFH and its five related genes (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732e0bcb18f71ec36b290d0afad9c9d8
http://edoc.mdc-berlin.de/21545/1/21545oa.pdf
http://edoc.mdc-berlin.de/21545/1/21545oa.pdf
Autor:
David V. Milford, Claire L. Harris, Janet Craze, Edwin K.S. Wong, Jonathan Evans, Vicky Brocklebank, Michael Freundlich, Jayanthi Chandar, Kevin J. Marchbank, Patrick R. Walsh, David J. Kavanagh, Caroline Jones, Martin Mraz, Gurinder Kumar, Kate Smith-Jackson, Michal Malina, William Wong, Bronte M. Corner, Eric Finlay, John O. Connolly, Stephen D. Marks, Alexander J. Howie, Neil S. Sheerin, Carol Inward, Sally Johnson, Daniel P. Gale, Valerie Wilson
Publikováno v:
Kidney International
Recessive mutations in diacylglycerol kinase epsilon (DGKE) display genetic pleiotropy, with pathological features reported as either thrombotic microangiopathy or membranoproliferative glomerulonephritis (MPGN), and clinical features of atypical hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2f2f676ecd81eb02e57e8bcb469ad8
https://doi.org/10.1016/j.kint.2020.01.045
https://doi.org/10.1016/j.kint.2020.01.045
Publikováno v:
Gastrointestinal Endoscopy Clinics of North America. 30:291-307
Minimally invasive endoscopic antireflux therapies are critical for bridging the gap between medical and surgical treatments for gastroesophageal reflux disease (GERD). Although multiple endoscopic devices have been developed, perhaps some of the mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e8b9d996dff91a4faaf367cd8c2022
https://doi.org/10.1016/j.giec.2019.12.009
https://doi.org/10.1016/j.giec.2019.12.009
Autor:
Edwin K. S. Wong, Thomas M. Hallam, Vicky Brocklebank, Patrick R. Walsh, Kate Smith-Jackson, Victoria G. Shuttleworth, Thomas E. Cox, Holly E. Anderson, Paul Nigel Barlow, Kevin James Marchbank, Claire L. Harris, David Kavanagh
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology, Vol 11 (2021)
Membranoproliferative glomerulonephritis (MPGN), C3 glomerulopathy (C3G), atypical haemolytic uraemic syndrome (aHUS) and age-related macular degeneration (AMD) have all been strongly linked with dysfunction of the alternative pathway (AP) of complem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82600a200f9bbe4fcd168a57def94528
https://pubmed.ncbi.nlm.nih.gov/33519811
https://pubmed.ncbi.nlm.nih.gov/33519811
Publikováno v:
Biophysical Journal. 121:271a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdea8bf5f59b0287f72d3a8d6d947933
https://doi.org/10.1016/j.bpj.2021.11.1388
https://doi.org/10.1016/j.bpj.2021.11.1388
Autor:
Andrew R. Gennery, Persis Amrolia, David J. Kavanagh, Reem Elfeky, Stephen Owens, Joseph F. Standing, Robert Chiesa, Patrick R. Walsh, Austen Worth, Su-Han Lum, Helen K. Young, Kanchan Rao, Zohreh Nademi, Roderick Skinner, A Battersby, Claire Booth, Andrew J. Cant, Sinead Greener, Paul Veys, Mary Slatter, Giorgio Ottaviano, Natalia Builes, Bilyana Doncheva, Terence J. Flood, Waseem Qasim, Srinivas Annavarapu, Giovanna Lucchini
Publikováno v:
Blood Adv
This study aimed to identify a risk profile for development of transplant-associated thrombotic microangiopathy (TA-TMA) in children undergoing hematopoietic stem cell transplantation (HSCT). Between 2013 and 2016, 439 children underwent 474 HSCTs at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dab06175d95bd84347e83abd99267b4
https://pubmed.ncbi.nlm.nih.gov/32492158
https://pubmed.ncbi.nlm.nih.gov/32492158