Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Patrick R. Smith"'
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102717- (2023)
Summary: Sensory neurons play pervasive roles throughout biology. In vitro studies to probe their functions hinge on the successful application of primary cell culture. Here, we present a protocol for the isolation and culture of mouse dorsal root ga
Externí odkaz:
https://doaj.org/article/82855a507c1d457493dc978f5b99b54d
Autor:
Patrick R. Smith, Sarah Loerch, Nikesh Kunder, Alexander D. Stanowick, Tzu-Fang Lou, Zachary T. Campbell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Processing bodies are phase separated compartments enriched in translationally repressed mRNAs. Here, Smith et al. show that, in sensory neurons, eukaryotic elongation factor 2 kinase (eEF2K) plays key roles in the regulation of processing body abund
Externí odkaz:
https://doaj.org/article/9c6a9fbaa8f14bc3a227f43bf19fed84
Autor:
Rebecca Chase, June Bryan de la Peña, Patrick R. Smith, Jennifer Lawson, Tzu‐Fang Lou, Alexander D. Stanowick, Bryan J. Black, Zachary T. Campbell
Publikováno v:
FASEB J
Nociceptors are a type of sensory neuron that are integral to most forms of pain. Targeted disruption of nociceptor sensitization affords unique opportunities to prevent pain. An emerging model for nociceptors are sensory neurons derived from human s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2997c52cab988f44896a957601166f67
https://europepmc.org/articles/PMC10227861/
https://europepmc.org/articles/PMC10227861/
Publikováno v:
WIREs Mechanisms of Disease. 14
The development of novel pain therapeutics hinges on the identification and rigorous validation of potential targets. Model organisms provide a means to test the involvement of specific genes and regulatory elements in pain. Here we provide a list of
Publikováno v:
Trends in biochemical sciences, vol 47, iss 6
Trends Biochem Sci
Trends Biochem Sci
In addition to their central functions in translation, ribosomes can adopt inactive structures that are fully assembled yet devoid of mRNA. We describe how the abundance of idle eukaryotic ribosomes is influenced by a broad range of biological condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a737cb9e975f2a3971e3846a6f0acf4e
https://escholarship.org/uc/item/2nq0x9k8
https://escholarship.org/uc/item/2nq0x9k8
Publikováno v:
Biophysical Journal. 122:345a
Autor:
Tzu-Fang Lou, Patrick R. Smith, Sarah Loerch, Alexander D. Stanowick, Zachary T. Campbell, Nikesh Kunder
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature communications, vol 12, iss 1
Processing bodies (p-bodies) are a prototypical phase-separated RNA-containing granule. Their abundance is highly dynamic and has been linked to translation. Yet, the molecular mechanisms responsible for coordinate control of the two processes are un
Autor:
Rebecca Chase, June Bryan de la Peña, Patrick R. Smith, Jennifer M. Lawson, Tzu-Fang Lou, Alexander D. Stanowick, Bryan J. Black, Zachary Campbell
Publikováno v:
The Journal of Pain. 23:37-38
Autor:
Patrick R. Smith, Alexander D. Stanowick, Zachary T. Campbell, Nikesh Kunder, Sarah Loerch, Tzu-Fang Lou
Processing bodies (p-bodies) are a prototypical phase-separated RNA-containing granule. Their abundance is highly dynamic and has been linked to translation. Yet, the molecular mechanisms responsible for coordinate control of the two processes are un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::246517c0a69cce0839983fa8638a93c0
https://doi.org/10.1101/2021.08.11.455974
https://doi.org/10.1101/2021.08.11.455974
Publikováno v:
Journal of Clinical Sleep Medicine. 15:1529-1533
The effect of hormone therapy on sleep-disordered breathing in transgender patients has not been described. We present three cases of patients undergoing gender reassignment and treated with hormon...