Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Patrick R. Shiflett"'
Publikováno v:
Journal of Molecular Recognition. 18:73-83
Staphylococcal enterotoxins SEB and SEC3 and toxic shock syndrome toxin TSST-1 act as superantigens by overstimulating the human immune system and thereby compromise host defense. The mechanism of pathogenesis is explained on the basis of superantige
Publikováno v:
Journal of Biological Chemistry. 279:5676-5684
The Staphylococcus aureus enterotoxins (S.E.) A-I, and toxic-shock syndrome toxin TSST-1 act as superantigens to cause overstimulation of the host immune system, leading to the onset of various diseases including food poisoning and toxic shock syndro
Autor:
Patrick R. Shiflett, Louis A. Silks, Ryszard Michalczyk, Goutam Gupta, Kirsten J. Taylor-McCabe
Publikováno v:
Biochemistry. 42:6078-6089
Three proteins, namely, protective antigen (PA), edema factor (EF), and lethal factor (LF), encoded by the pX01 plasmid of Bacillus anthracis play a major role in the pathogenesis of target host cells. PA combines with EF and LF to form bipartite PA-
Publikováno v:
Journal of molecular recognition : JMR. 18(1)
Staphylococcal enterotoxins SEB and SEC3 and toxic shock syndrome toxin TSST-1 act as superantigens by overstimulating the human immune system and thereby compromise host defense. The mechanism of pathogenesis is explained on the basis of superantige
Publikováno v:
The Journal of biological chemistry. 279(7)
The Staphylococcus aureus enterotoxins (S.E.) A-I, and toxic-shock syndrome toxin TSST-1 act as superantigens to cause overstimulation of the host immune system, leading to the onset of various diseases including food poisoning and toxic shock syndro
Autor:
Goutam Gupta, N. M. Lehnert, Bruce E. Lehnert, David L. Allen, Beth Allen, Patrick R. Shiflett, Michael Chen, P. Catasti
Publikováno v:
Biochemistry. 40(14)
Key surface proteins of pathogens and their toxins bind to the host cell receptors in a manner that is quite different from the way the natural ligands bind to the same receptors and direct normal cellular responses. Here we describe a novel strategy