Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Patrick R. Gleason"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Structural characterization of small molecules is a crucial component of organic synthesis. In this work, we applied microcrystal electron diffraction (MicroED) to analyze the structure of the product of an enzymatic reaction that was intended to pro
Externí odkaz:
https://doaj.org/article/fdd1b25f424c417b89c4258541a6fc6b
Publikováno v:
Org Biomol Chem
We describe an approach for the development of fluorescent sensors of metabolite binding in which a genetically encoded fluorescent non-canonical amino acid (fNCAA) containing a 7-hydroxycoumarin moiety (7-HCAA) forms a FRET pair with native tryptoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7babd35955dcc8a5a32129a1b0bcec8f
https://doi.org/10.1039/d0ob00793e
https://doi.org/10.1039/d0ob00793e
Autor:
Patrick R. Gleason, Chad R. Simmons, J. Nathan Henderson, Jeremy H. Mills, Bethany Kolbaba-Kartchner, Erik P Stahl
Publikováno v:
Biochemistry
Fluorescent noncanonical amino acids (fNCAAs) could serve as starting points for the rational design of protein-based fluorescent sensors of biological activity. However, efforts toward this goal are likely hampered by a lack of atomic-level characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5fc0cf889b1f2406ce07e9c3796baa
https://europepmc.org/articles/PMC8879415/
https://europepmc.org/articles/PMC8879415/
Publikováno v:
J Am Chem Soc
Synthetic auxotrophy in which bacterial viability depends on the presence of a synthetic amino acid provides a robust strategy for the containment of genetically modified organisms and the development of safe, live vaccines. However, a simple, genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b1e8446fe69b9ca68f04df4e3ff32d
https://doi.org/10.1021/jacs.9b08491
https://doi.org/10.1021/jacs.9b08491
Autor:
Bethany Kolbaba-Kartchner, Patrick R. Gleason, Jeremy H. Mills, J.N. Henderson, Chad R. Simmons
Fluorescent non-canonical amino acids (fNCAAs) could serve as starting points for the rational design of protein-based fluorescent sensors of biological activity. However, efforts toward this goal are likely hampered by a lack of atomic-level charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaa33ff7844f7a6ae21a22ea04d42739
https://doi.org/10.1101/2021.04.24.441261
https://doi.org/10.1101/2021.04.24.441261
Publikováno v:
Protein expression and purification. 175
The high-flux/low-affinity cyanobacterial bicarbonate transporter BicA is a member of sulfate permease/solute carrier 26 (SulP/SLC26) family and plays a major role in cyanobacterial inorganic carbon uptake. In order to study this important membrane p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4547df3e2c2254628c338444c15ec1f2
https://pubmed.ncbi.nlm.nih.gov/32738437
https://pubmed.ncbi.nlm.nih.gov/32738437