Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Patrick R, Hannon"'
Publikováno v:
Molecular Reproduction and Development. 89:608-631
Exposure to endocrine-disrupting chemicals (EDCs) is unavoidable, which represents a public health concern given the ability of EDCs to target the ovary. However, there is a large gap in the knowledge about the impact of EDCs on ovarian function, inc
Autor:
Joseph A. Cacioppo, Po-Ching Patrick Lin, Patrick R. Hannon, Daniel R. McDougle, Arnon Gal, CheMyong Ko
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Ovulation is dependent upon numerous factors mediating follicular growth, vascularization, and ultimately oocyte release via follicle rupture. Endothelin-2 (EDN2) is a potent vasoconstrictor that is transiently produced prior to follicle rup
Externí odkaz:
https://doaj.org/article/c60aa4525a74446b848c5da148aeb77f
Autor:
Ketan Shrestha, Linah Al-Alem, Priscilla Garcia, Michelle A A Wynn, Patrick R Hannon, Misung Jo, Jenny Drnevich, Diane M Duffy, Thomas E Curry Jr
Publikováno v:
Biology of reproduction.
The luteinizing hormone (LH) surge induces paracrine mediators within the ovarian follicle that promote ovulation. The present study explores neurotensin (NTS), a neuropeptide, as a potential ovulatory mediator in the mouse ovary. Ovaries and granulo
Autor:
Arnon Gal, Po-Ching Lin, Joseph A Cacioppo, Patrick R Hannon, Megan M Mahoney, Andrew Wolfe, Rodrigo Fernandez-Valdivia, John P Lydon, Carol F Elias, CheMyong Ko
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159534 (2016)
Ovarian steroids, estradiol and progesterone, play central roles in regulating female reproduction by acting as both positive and negative regulators of gonadotropin-releasing hormone (GnRH) secretion in the hypothalamus. Recent studies have identifi
Externí odkaz:
https://doaj.org/article/f8a17fd0d04946938a2cb1c1767f4ac8
Publikováno v:
Toxicol Sci
Phthalates are solvents and plasticizers found in consumer products including cosmetics, food/beverage containers, housing materials, etc. Phthalates are known endocrine-disrupting chemicals that can directly target the ovary, potentially causing def
Autor:
Diane M. Duffy, Katherine L. Rosewell, Thomas E. Curry, Patrick R. Hannon, Mats Brännström, James W. Akin
Publikováno v:
Endocrinology. 159:2447-2458
The luteinizing hormone (LH) surge is essential for ovulation, but the intrafollicular factors induced by LH that mediate ovulatory processes (e.g., angiogenesis) are poorly understood, especially in women. The role of secretogranin II (SCG2) and its
Autor:
Jodi A. Flaws, Kadeem A. Richardson, Maung Sun Myint, Romana A. Nowak, Yvette J. Johnson-Walker, Patrick R. Hannon
Publikováno v:
Reproductive Toxicology. 77:70-79
Di-(2-ethylhexyl) phthalate (DEHP) is an endocrine-disrupting chemical that has been shown to impair normal reproductive function in males and females. This study investigated whether adult exposure to environmental and occupational doses of DEHP alt
Autor:
Katherine L. Rosewell, Yohan Choi, Patrick R. Hannon, Mats Brännström, Thomas E. Curry, James W. Akin, Kalin Wilson, Misung Jo
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Context: In animal models, the luteinizing hormone surge increases progesterone (P4) and progesterone receptor (PGR), prostaglandins (PTGs), and epidermal growth factor (EGF)–like factors that play essential roles in ovulation. However, little is k
Publikováno v:
Toxicological Sciences. 150:97-108
Humans are ubiquitously exposed to di(2-ethylhexyl) phthalate (DEHP), which is an environmental toxicant incorporated in consumer products. Studies have shown that DEHP targets the ovary to disrupt essential processes required for reproductive and no