Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Patrick Petzsch"'
Autor:
Annette Limke, Gereon Poschmann, Kai Stühler, Patrick Petzsch, Thorsten Wachtmeister, Anna von Mikecz
Publikováno v:
Journal of Xenobiotics, Vol 14, Iss 1, Pp 135-153 (2024)
The incidence of age-related neurodegenerative diseases is rising globally. However, the temporal sequence of neurodegeneration throughout adult life is poorly understood. To identify the starting points and schedule of neurodegenerative events, sero
Externí odkaz:
https://doaj.org/article/6c1b0ecc443e4ea9bf2ffb2b0428dc02
Autor:
Ylenia Longo, Sara Moreno Mascaraque, Giuseppe Andreacchio, Julia Werner, Ichiro Katahira, Elena De Marchi, Anna Pegoraro, Robert Jan Lebbink, Karl Köhrer, Patrick Petzsch, Ronny Tao, Francesco Di Virgilio, Elena Adinolfi, Ingo Drexler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionModified Vaccinia Virus Ankara (MVA) is a safe vaccine vector inducing long- lasting and potent immune responses. MVA-mediated CD8+T cell responses are optimally induced, if both, direct- and cross-presentation of viral or recombinant ant
Externí odkaz:
https://doaj.org/article/c51d0799a12d4c9e9a19762506b18869
Autor:
Alfonso Schiavi, Claudia Cirotti, Lora-Sophie Gerber, Giulia Di Lauro, Silvia Maglioni, Priscila Yumi Tanaka Shibao, Sabrina Montresor, Janine Kirstein, Patrick Petzsch, Karl Köhrer, Roel P. F. Schins, Tina Wahle, Daniela Barilà, Natascia Ventura
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-22 (2023)
Abstract Alzheimer’s disease is the most common age-associated neurodegenerative disorder and the most frequent form of dementia in our society. Aging is a complex biological process concurrently shaped by genetic, dietary and environmental factors
Externí odkaz:
https://doaj.org/article/b943984ede4d4379a2a87b1088dc502b
Autor:
Puyan Rafii, Christiane Seibel, Hendrik T. Weitz, Julia Ettich, Anna Rita Minafra, Patrick Petzsch, Alexander Lang, Doreen M. Floss, Kristina Behnke, Karl Köhrer, Jens M. Moll, Jürgen Scheller
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract All except one cytokine of the Interleukin (IL-)6 family share glycoprotein (gp) 130 as the common β receptor chain. Whereas Interleukin (IL-)11 signal via the non-signaling IL-11 receptor (IL-11R) and gp130 homodimers, leukemia inhibitory
Externí odkaz:
https://doaj.org/article/4e5af694c75a4cba811637e4b68d6f48
Autor:
Lucie M. Frerichs, Bastian Frerichs, Patrick Petzsch, Karl Köhrer, Joachim Windolf, Bernd Bittersohl, Michèle J. Hoffmann, Vera Grotheer
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundPatients with muscle-invasive bladder cancer face a poor prognosis due to rapid disease progression and chemoresistance. Thus, there is an urgent need for a new therapeutic treatment. The tumor microenvironment (TME) has crucial roles in tu
Externí odkaz:
https://doaj.org/article/d1b1c94943b94a40b371c72ab6b00761
Autor:
Margaretha A. Skowron, Katharina Eul, Alexa Stephan, Gillian F. Ludwig, Gamal A. Wakileh, Arthur Bister, Christian Söhngen, Katharina Raba, Patrick Petzsch, Gereon Poschmann, Edmund Osei Kuffour, Daniel Degrandi, Shafaqat Ali, Constanze Wiek, Helmut Hanenberg, Carsten Münk, Kai Stühler, Karl Köhrer, Elvira Mass, Daniel Nettersheim
Publikováno v:
Molecular Oncology, Vol 16, Iss 17, Pp 3107-3127 (2022)
The tumor microenvironment (TM), consisting of the extracellular matrix (ECM), fibroblasts, endothelial cells, and immune cells, might affect tumor invasiveness and the outcome of standard chemotherapy. This study investigated the cross talk between
Externí odkaz:
https://doaj.org/article/ffe3528d607a4047bb2b60d1084aaa8d
Autor:
Ananda Ayyappan Jaguva Vasudevan, Michèle J. Hoffmann, Gereon Poschmann, Patrick Petzsch, Constanze Wiek, Kai Stühler, Karl Köhrer, Wolfgang A. Schulz, Günter Niegisch
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-7 (2022)
Measurement(s) RNA-seq assay • Proteome Technology Type(s) Whole Transcriptome Sequencing • Mass spectrometry intensity based label-free quantification method Factor Type(s) Effect of HDAC5 overexpression in a range of urothelial cancer cells Sam
Externí odkaz:
https://doaj.org/article/31a9b4a026c34b6694b497aa3c502bac
Autor:
Margaretha A. Skowron, Teresa K. Becker, Lukas Kurz, Sina Jostes, Felix Bremmer, Florian Fronhoffs, Kai Funke, Gamal A. Wakileh, Melanie R. Müller, Aaron Burmeister, Thomas Lenz, Anja Stefanski, Kai Stühler, Patrick Petzsch, Karl Köhrer, Peter Altevogt, Peter Albers, Glen Kristiansen, Hubert Schorle, Daniel Nettersheim
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 982-1008 (2022)
Testicular germ cell tumors (GCTs) are stratified into seminomas and nonseminomas. Seminomas share many histological and molecular features with primordial germ cells, whereas the nonseminoma stem cell population—embryonal carcinoma (EC)—is pluri
Externí odkaz:
https://doaj.org/article/8b019692a23e4a8fbca36ce693337779
Autor:
Rianne Nederlof, Sophia Reidel, André Spychala, Stefanie Gödecke, André Heinen, Tobias Lautwein, Patrick Petzsch, Karl Köhrer, Axel Gödecke
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Acute myocardial infarction (MI) induces an extensive sterile inflammation, which is dominated in the early phase by invading neutrophils and monocytes/macrophages. The inflammatory response after MI critically affects infarct healing and cardiac rem
Externí odkaz:
https://doaj.org/article/ddfa61368cbc44b1ba436e2e13f4bc20
Autor:
Anne K. E. Brüning, Jennifer L. Schiefer, Paul C. Fuchs, Patrick Petzsch, Karl Köhrer, Christoph V. Suschek, Ewa K. Stürmer, Christian Opländer
Publikováno v:
Life, Vol 13, Iss 2, p 331 (2023)
Hypertrophic scarring in burn wounds is caused by overactive fibroblasts and myofibroblasts. Blue light reveals wavelength- and dose-dependent antibacterial and antiproliferative effects and may serve as a therapeutic option against wound infection a
Externí odkaz:
https://doaj.org/article/7c26b86d16494d14a37c68fbd9781b05