Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Patrick Pence"'
Autor:
Nancy D. Marin, Michelle Becker-Hapak, Wilbur M. Song, Quazim A. Alayo, Lynne Marsala, Naomi Sonnek, Melissa M. Berrien-Elliott, Mark Foster, Jennifer A. Foltz, Jennifer Tran, Pamela Wong, Celia C. Cubitt, Patrick Pence, Kimberly Hwang, Alice Y. Zhou, Miriam T. Jacobs, Timothy Schappe, David A. Russler-Germain, Ryan C. Fields, Matthew A. Ciorba, Todd A. Fehniger
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTMetastatic (m) colorectal cancer (CRC) is an incurable disease with a poor prognosis and thus remains an unmet clinical need. Immune checkpoint blockade (ICB)-based immunotherapy is effective for mismatch repair-deficient (dMMR)/microsatellit
Externí odkaz:
https://doaj.org/article/989a296ad9bc48bf902f4f5ef1d3f555
Autor:
Pamela Wong, Jennifer A. Foltz, Lily Chang, Carly C. Neal, Tony Yao, Celia C. Cubitt, Jennifer Tran, Samantha Kersting-Schadek, Sathvik Palakurty, Natalia Jaeger, David A. Russler-Germain, Nancy D. Marin, Margery Gang, Julia A. Wagner, Alice Y. Zhou, Miriam T. Jacobs, Mark Foster, Timothy Schappe, Lynne Marsala, Ethan McClain, Patrick Pence, Michelle Becker-Hapak, Bryan Fisk, Allegra A. Petti, Obi L. Griffith, Malachi Griffith, Melissa M. Berrien-Elliott, Todd A. Fehniger
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Since the T-box transcription factors (TFs) T-BET and EOMES are necessary for initiation of NK cell development, their ongoing requirement for mature NK cell homeostasis, function, and molecular programming remains unclear. To address this, T-BET and
Externí odkaz:
https://doaj.org/article/74062db604294ed99bc9e3922c1fadcb
Autor:
Samantha VH Bayer, Whitney R Grither, Audrey Brenot, Priscilla Y Hwang, Craig E Barcus, Melanie Ernst, Patrick Pence, Christopher Walter, Amit Pathak, Gregory D Longmore
Publikováno v:
eLife, Vol 8 (2019)
Biomechanical changes in the tumor microenvironment influence tumor progression and metastases. Collagen content and fiber organization within the tumor stroma are major contributors to biomechanical changes (e., tumor stiffness) and correlated with
Externí odkaz:
https://doaj.org/article/eab383b9c0cb49e7be6e667bc5b80fbf
Autor:
Todd A. Fehniger, Hing C. Wong, Melissa M. Berrien-Elliott, Ryan P. Sullivan, Caitlin A. Prendes, Emily K. Jeng, Gabriela J. Muniz, Jin-an Jiao, Peter R. Rhode, Jack O. Egan, Lijing You, Laritza L. Ramirez, Christian A. Echeverri, Victor L. Gallo, Catherine M. Spanoudis, Xiaoyun Zhu, David A. Russler-Germain, Julia A. Wagner, Pamela Wong, Patrick Pence, Carly C. Neal, Sweta Desai, Jennifer Tran, Timothy Schappe, Mark Foster, Lynne I. Marsala, Gilles M. Leclerc, Pallavi Chaturvedi, Michael J. Dee, Ethan McClain, Niraj Shrestha, Michelle K. Becker-Hapak
Table 4 Excel Document
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b37f93cfd209711d0af372f7b061071
https://doi.org/10.1158/2326-6066.22543666
https://doi.org/10.1158/2326-6066.22543666
Autor:
Todd A. Fehniger, Hing C. Wong, Melissa M. Berrien-Elliott, Ryan P. Sullivan, Caitlin A. Prendes, Emily K. Jeng, Gabriela J. Muniz, Jin-an Jiao, Peter R. Rhode, Jack O. Egan, Lijing You, Laritza L. Ramirez, Christian A. Echeverri, Victor L. Gallo, Catherine M. Spanoudis, Xiaoyun Zhu, David A. Russler-Germain, Julia A. Wagner, Pamela Wong, Patrick Pence, Carly C. Neal, Sweta Desai, Jennifer Tran, Timothy Schappe, Mark Foster, Lynne I. Marsala, Gilles M. Leclerc, Pallavi Chaturvedi, Michael J. Dee, Ethan McClain, Niraj Shrestha, Michelle K. Becker-Hapak
Supplemental Figures 1-8, Supplemental Tables 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e13f7fc0e20067d5cd1db53ac7d4496
https://doi.org/10.1158/2326-6066.22543672.v1
https://doi.org/10.1158/2326-6066.22543672.v1
Autor:
Todd A. Fehniger, Hing C. Wong, Melissa M. Berrien-Elliott, Ryan P. Sullivan, Caitlin A. Prendes, Emily K. Jeng, Gabriela J. Muniz, Jin-an Jiao, Peter R. Rhode, Jack O. Egan, Lijing You, Laritza L. Ramirez, Christian A. Echeverri, Victor L. Gallo, Catherine M. Spanoudis, Xiaoyun Zhu, David A. Russler-Germain, Julia A. Wagner, Pamela Wong, Patrick Pence, Carly C. Neal, Sweta Desai, Jennifer Tran, Timothy Schappe, Mark Foster, Lynne I. Marsala, Gilles M. Leclerc, Pallavi Chaturvedi, Michael J. Dee, Ethan McClain, Niraj Shrestha, Michelle K. Becker-Hapak
Natural killer (NK) cells are a promising cellular therapy for cancer, with challenges in the field including persistence, functional activity, and tumor recognition. Briefly, priming blood NK cells with recombinant human (rh)IL-12, rhIL-15, and rhIL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60502031d460156d184870efe3c110c9
https://doi.org/10.1158/2326-6066.c.6550354.v1
https://doi.org/10.1158/2326-6066.c.6550354.v1
Autor:
Todd A. Fehniger, Hing C. Wong, Melissa M. Berrien-Elliott, Ryan P. Sullivan, Caitlin A. Prendes, Emily K. Jeng, Gabriela J. Muniz, Jin-an Jiao, Peter R. Rhode, Jack O. Egan, Lijing You, Laritza L. Ramirez, Christian A. Echeverri, Victor L. Gallo, Catherine M. Spanoudis, Xiaoyun Zhu, David A. Russler-Germain, Julia A. Wagner, Pamela Wong, Patrick Pence, Carly C. Neal, Sweta Desai, Jennifer Tran, Timothy Schappe, Mark Foster, Lynne I. Marsala, Gilles M. Leclerc, Pallavi Chaturvedi, Michael J. Dee, Ethan McClain, Niraj Shrestha, Michelle K. Becker-Hapak
Legends for Supplementary Figures 1-8 and Supplementary Tables 1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fa6d74b7fbe9cd7616d5eb28664fc1
https://doi.org/10.1158/2326-6066.22543675
https://doi.org/10.1158/2326-6066.22543675
Autor:
Todd A. Fehniger, Hing C. Wong, Melissa M. Berrien-Elliott, Ryan P. Sullivan, Caitlin A. Prendes, Emily K. Jeng, Gabriela J. Muniz, Jin-an Jiao, Peter R. Rhode, Jack O. Egan, Lijing You, Laritza L. Ramirez, Christian A. Echeverri, Victor L. Gallo, Catherine M. Spanoudis, Xiaoyun Zhu, David A. Russler-Germain, Julia A. Wagner, Pamela Wong, Patrick Pence, Carly C. Neal, Sweta Desai, Jennifer Tran, Timothy Schappe, Mark Foster, Lynne I. Marsala, Gilles M. Leclerc, Pallavi Chaturvedi, Michael J. Dee, Ethan McClain, Niraj Shrestha, Michelle K. Becker-Hapak
Table 5 Excel Document
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ba2d66c09953f18e407d4146db2e73
https://doi.org/10.1158/2326-6066.22543663.v1
https://doi.org/10.1158/2326-6066.22543663.v1
Autor:
Ethan McClain, Sweta Desai, Amanda F. Cashen, Mark P. Foster, Peter Westervelt, Patrick Soon-Shiong, Michelle Becker-Hapak, Keith Stockerl-Goldstein, Jeffrey S. Miller, Miriam T. Jacobs, Mark A. Schroeder, Pamela Wong, Camille N. Abboud, Patrick Pence, Geoffrey L. Uy, Feng Gao, Claudio G. Brunstein, Melissa M. Berrien-Elliott, Meagan A. Jacoby, Iskra Pusic, Sarah Cooley, John F. DiPersio, Todd A. Fehniger
Publikováno v:
Blood. 139:1177-1183
Natural killer (NK) cells are a promising alternative to T cells for cancer immunotherapy. Adoptive therapies with allogeneic, cytokine-activated NK cells are being investigated in clinical trials. However, the optimal cytokine support after adoptive
Autor:
Pamela Wong, Jin-An Jiao, Timothy Schappe, Gilles M. Leclerc, Sweta Desai, Gabriela J. Muniz, Melissa M. Berrien-Elliott, Mark P. Foster, Lynne Marsala, Pallavi Chaturvedi, Carly Neal, Niraj Shrestha, Christian A. Echeverri, Xiaoyun Zhu, David A. Russler-Germain, Caitlin A. Prendes, Catherine M. Spanoudis, Todd A. Fehniger, Ethan McClain, Jack O. Egan, Michael J. Dee, Peter R. Rhode, Hing C. Wong, Jennifer Tran, Laritza L. Ramirez, Ryan P. Sullivan, Lijing You, Victor L. Gallo, Julia A. Wagner, Emily K. Jeng, Michelle Becker-Hapak, Patrick Pence
Publikováno v:
Cancer Immunol Res
Natural killer (NK) cells are a promising cellular therapy for cancer, with challenges in the field including persistence, functional activity, and tumor recognition. Briefly, priming blood NK cells with recombinant human (rh)IL-12, rhIL-15, and rhIL