Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Patrick P. J. Mulder"'
Autor:
Dvory Namdar, Patrick P. J. Mulder, Eyal Ben-Simchon, Yael Hacham, Loai Basheer, Ofer Cohen, Marcelo Sternberg, Oren Shelef
Publikováno v:
Toxins, Vol 16, Iss 3, p 163 (2024)
Alkaloids play an essential role in protecting plants against herbivores. Humans can also benefit from the pharmacological effects of these compounds. Plants produce an immense variety of structurally different alkaloids, including quinolizidine alka
Externí odkaz:
https://doaj.org/article/5b14c566f6ed42699b4f6916bc9f6231
Publikováno v:
Toxins, Vol 15, Iss 2, p 98 (2023)
The occurrence of tropane alkaloids (TAs), toxic plant metabolites, in food in Europe was studied to identify those TAs in food most relevant for human health. Information was extracted from the literature and the 2016 study from the European Food Sa
Externí odkaz:
https://doaj.org/article/590f3205bacb474ca9bd6c01f82efc7a
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
The evolution of increased competitive ability (EICA) hypothesis and the shifting defense hypothesis (SDH) predict that evolutionary changes occur in a suite of traits related to defense and growth in invasive plant species as result of the absence o
Externí odkaz:
https://doaj.org/article/12bfb5c72b2b486b8e50408057379278
Publikováno v:
Molecules, Vol 26, Iss 3, p 689 (2021)
Pyrrolizidine alkaloids (PAs) are genotoxic carcinogenic phytotoxins mostly prevalent in the Boraginaceae, Asteraceae and Fabaceae families. Heliotropium species (Boraginaceae) are PA-producing weeds, widely distributed in the Mediterranean region, t
Externí odkaz:
https://doaj.org/article/daed57c2f9b64da6a85d869d336aa833
Publikováno v:
Toxins, Vol 12, Iss 4, p 243 (2020)
Cardiac glycosides (CGs) are naturally occurring plant secondary metabolites that can be toxic to humans and animals. The aim of this work was to develop a targeted analytical method utilizing liquid chromatography—tandem mass spectrometry (LC-MS/M
Externí odkaz:
https://doaj.org/article/19feeb57829d42bf97980948cf2051cc
Autor:
Jochem Louisse, Patrick P. J. Mulder, Arjen Gerssen, Geert Stoopen, Deborah Rijkers, Milou G. M. van de Schans, Ad A. C. M. Peijnenburg
Publikováno v:
Archives of Toxicology 96 (2022) 8
Archives of Toxicology, 96(8), 2299-2317
Archives of Toxicology, 96(8), 2299-2317
Pyrrolizidine alkaloids (PAs) are produced by various plant species and have been detected as contaminants in food and feed. Monitoring programmes should include PAs that are present in relevant matrices and that exhibit a high toxic potential. The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1a7aa2e45031d8728edbbbed7cd66c
https://research.wur.nl/en/publications/bioassay-directed-analysis-based-identification-of-relevant-pyrro
https://research.wur.nl/en/publications/bioassay-directed-analysis-based-identification-of-relevant-pyrro
Publikováno v:
PeerJ
Biological invasion is regarded as one of the greatest environmental problems facilitated by globalization. Some hypotheses about the invasive mechanisms of alien invasive plants consider the plant–herbivore interaction and the role of plant defens
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 112:22-32
The synthesis of nine isomeric methyl-substituted acephenanthrylenes is described. Three different approaches were used. 1-, 2-, And 6-methylacephenanthrylene (1a, 1c and 1f) were prepared by formylation of acephenanthrene (2) and 4,5,7,8,9,10-hexahy
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 109:463-466
The synthesis and characterization of cyclopent[hi]aceanthrylene, a novel dicyclopenta-fused polycyclic hydrocarbon, are described. The key step is the reductive double alkylation of anthracene by lithium bromoacetate in liquid ammonia giving cis-9,1
Autor:
Jan Cornelisse, Jia-Sheng Wang, Xia He, William F. Busby, Ben B. Boere, Patrick P. J. Mulder, Johan Lugtenburg
Publikováno v:
Carcinogenesis. 20:1137-1141
Cyclopenta-fused polycyclic aromatic hydrocarbons are ubiquitous environmental pollutants and potential human health biohazards. In this study, the tumorigenicity of three single cyclopenta-fused polycyclic aromatic hydrocarbons, aceanthrylene, dihyd