Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Patrick P. DeLuca"'
Publikováno v:
International Journal of Biomaterials, Vol 2014 (2014)
In this study, four PLGA microsphere formulations of Olanzapine were characterized on the basis of their in vitro behavior at 37°C, using a dialysis based method, with the goal of obtaining an IVIVC. In vivo profiles were determined by deconvolution
Externí odkaz:
https://doaj.org/article/53b190e79f7d4b3aa7a3ca3cc7332bda
Publikováno v:
AAPS PharmSciTech. 19:2264-2275
The purpose of this study was to develop pirfenidone (PF) ointment formulations for a dose finding study in the prophylactic treatment of deep partial-thickness burns in a mouse model. A preformulation study was performed to evaluate the solubility o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2ac59f0125cbbafa49b3178ab3cecf
https://doi.org/10.1208/s12249-018-1030-3
https://doi.org/10.1208/s12249-018-1030-3
Autor:
Patrick P. DeLuca, Madhav S. Kamat
Publikováno v:
Parenteral Medications ISBN: 9780429201400
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be0afe2f5a42c602a3dcb9812d3c0a34
https://doi.org/10.1201/9780429201400-12
https://doi.org/10.1201/9780429201400-12
Autor:
Patrick P. DeLuca, Julius Z. Knapp
Publikováno v:
Pharmaceutical Dosage Forms ISBN: 9780203743676
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28e95b3b424084d11a286c229825e583
https://doi.org/10.1201/9780203743676-3
https://doi.org/10.1201/9780203743676-3
Publikováno v:
Advances in Pharmaceutics. 2015:1-10
The purpose of this study was to examine the degradative effect of weakly basic nucleophilic drugs on a lactide-co-glycolide (PLGA) polymer in a microsphere formulation. Biodegradable PLGA microspheres of two second-generation atypical antipsychotics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2442cfbae157569f872dd4f89f80a64
https://doi.org/10.1155/2015/154239
https://doi.org/10.1155/2015/154239
Publikováno v:
Advances in Pharmaceutics. 2015:1-12
This study explores the mechanistic aspects of in vitro release from biodegradable microspheres with the objective of understanding the effect of the unstirred water layer on polymer degradation and drug release. In vitro drug release experiments on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d372604b834c3140f16be2202b86392d
https://doi.org/10.1155/2015/823476
https://doi.org/10.1155/2015/823476
Publikováno v:
Advances in Biomaterials. 2014:1-9
The objective of this study was to assess the physicochemical effects of hydrating a hydrophobic end-capped poly(lactide-co-glycolide) (PLGA) polymer in the liquid and vapor state. PLGA RG503 polymer was incubated at 37°C in 0.5% polyvinyl alcohol (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53b518607a4d79f47765f887a04ee451
https://doi.org/10.1155/2014/834942
https://doi.org/10.1155/2014/834942
Publikováno v:
Advances in Pharmaceutics. 2014:1-10
The objective of this study was to develop long-acting injectable dosage forms of Orntide, a peptide GnRH antagonist, to provide tailored release for 6-month duration. Using a polylactide homopolymer and the solvent extraction/evaporation method, thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::813e763174babd7f7ac789db538d534f
https://doi.org/10.1155/2014/435963
https://doi.org/10.1155/2014/435963
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 85:631-639
The purpose of this study was to develop a parenteral delivery system of Risperidone that would provide initial and extended drug release and thereby avoid the need for co-administration of oral tablets. Key formulation parameters utilized to achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4595920a5300b4495ad975ed9a6a58
https://doi.org/10.1016/j.ejpb.2013.07.012
https://doi.org/10.1016/j.ejpb.2013.07.012
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2013 (2013)
BioMed Research International, Vol 2013 (2013)
The purpose of this research was to develop a topical microsphere delivery system in a thermosensitive 20% poloxamer 407 gel (Pluronic F127) to control release of KSL-W, a cationic antimicrobial decapeptide, for a period of 4–7 days for potential a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b042fcf1ac3a12c849a9103c0d4ca782
https://doi.org/10.1155/2013/387863
https://doi.org/10.1155/2013/387863