Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Patrick Nasarre"'
Autor:
Harry A. Drabkin, Joëlle Roche, Robert M. Gemmill, Hellmut G. Augustin, Jonathan A. Clarhaut, Patrick Nasarre, Girish Sharma, Vincent A. Potiron
Loss of SEMA3F occurs frequently in lung cancer and correlates with advanced stage of disease. We previously reported that SEMA3F blocked tumor formation by H157 lung cancer cells in a rat orthotopic model. This was associated with loss of activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baf750543b7e966eba2df6c595219940
https://doi.org/10.1158/0008-5472.c.6496748
https://doi.org/10.1158/0008-5472.c.6496748
Autor:
Harry A. Drabkin, Philip H. Howe, Alessandro Lagana, Elizabeth Garrett-Mayer, Christopher Korch, Anna E. Barón, Xian Lu, Joëlle Roche, Vincent A. Potiron, Robert M. Gemmill, Patrick Nasarre
PDF file - 97K, shRNA target sequences (S1); Primers used for quantitative RT-PCR (S2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b796a908396b778be9807651414138a
https://doi.org/10.1158/0008-5472.22396707.v1
https://doi.org/10.1158/0008-5472.22396707.v1
Autor:
Hellmut G. Augustin, Ulrike Fiedler, Gavin Thurston, Dirk Schadendorf, Carleen Deppermann, Vivien Wolter, Iris Helfrich, Karoline Kruse, Markus Thomas, Patrick Nasarre
The angiopoietin/Tie2 system has been identified as the second vascular-specific receptor tyrosine kinase system controlling vessel assembly, maturation, and quiescence. Angiopoietin-2 (Ang-2) is prominently up-regulated in the host-derived vasculatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7575486f71cfb03aa44b6a58bd868181
https://doi.org/10.1158/0008-5472.c.6499280.v1
https://doi.org/10.1158/0008-5472.c.6499280.v1
Autor:
Harry A. Drabkin, Philip H. Howe, Alessandro Lagana, Elizabeth Garrett-Mayer, Christopher Korch, Anna E. Barón, Xian Lu, Joëlle Roche, Vincent A. Potiron, Robert M. Gemmill, Patrick Nasarre
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33add2cdbbb699a778ef87a4d61a8079
https://doi.org/10.1158/0008-5472.22396710
https://doi.org/10.1158/0008-5472.22396710
Autor:
Harry A. Drabkin, Philip H. Howe, Alessandro Lagana, Elizabeth Garrett-Mayer, Christopher Korch, Anna E. Barón, Xian Lu, Joëlle Roche, Vincent A. Potiron, Robert M. Gemmill, Patrick Nasarre
The epithelial–mesenchymal transition (EMT) and its reversal, mesenchymal–epithelial transition (MET), are fundamental processes involved in tumor cell invasion and metastasis. SEMA3F is a secreted semaphorin and tumor suppressor downregulated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c42501d5a0efce50e78dcc62d50e03
https://doi.org/10.1158/0008-5472.c.6504636
https://doi.org/10.1158/0008-5472.c.6504636
Autor:
Harry A. Drabkin, Philip H. Howe, Alessandro Lagana, Elizabeth Garrett-Mayer, Christopher Korch, Anna E. Barón, Xian Lu, Joëlle Roche, Vincent A. Potiron, Robert M. Gemmill, Patrick Nasarre
PDF file - 1864K, NRP2 is stably up-regulated by TGFβ in lung cancer cells without increasing the halflife of mRNA or protein (S1); NRP2 up-regulation is blocked by inhibition of TβRI, AKT, ERK and ZEB1, but not by expression of inhibitory SMAD7 (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a2d136b79ea18f701cfa8309630fb8
https://doi.org/10.1158/0008-5472.22396713
https://doi.org/10.1158/0008-5472.22396713
Autor:
Hellmut G. Augustin, Ulrike Fiedler, Gavin Thurston, Dirk Schadendorf, Carleen Deppermann, Vivien Wolter, Iris Helfrich, Karoline Kruse, Markus Thomas, Patrick Nasarre
Supplementary Figures 1-3 from Host-Derived Angiopoietin-2 Affects Early Stages of Tumor Development and Vessel Maturation but Is Dispensable for Later Stages of Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1605238ec2116216f34e819d9a3a27c1
https://doi.org/10.1158/0008-5472.22379555
https://doi.org/10.1158/0008-5472.22379555
Autor:
Harry A. Drabkin, Joëlle Roche, Robert M. Gemmill, Hellmut G. Augustin, Jonathan A. Clarhaut, Patrick Nasarre, Girish Sharma, Vincent A. Potiron
Supplementary Figure 1, Table 1, Methods and Materials from Semaphorin SEMA3F Affects Multiple Signaling Pathways in Lung Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b60ebed290e049fd7fb3e0ddb77bdd5
https://doi.org/10.1158/0008-5472.22371329
https://doi.org/10.1158/0008-5472.22371329
Autor:
Harry A. Drabkin, Philip H. Howe, Alessandro Lagana, Elizabeth Garrett-Mayer, Christopher Korch, Anna E. Barón, Xian Lu, Joëlle Roche, Vincent A. Potiron, Robert M. Gemmill, Patrick Nasarre
PDF file - 120K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8584fb01b16d5a79576046b5f25566
https://doi.org/10.1158/0008-5472.22396716.v1
https://doi.org/10.1158/0008-5472.22396716.v1
Autor:
Takeshi Yoshida, Lanxi Song, Yun Bai, Fumi Kinose, Jiannong Li, Kim C Ohaegbulam, Teresita Muñoz-Antonia, Xiaotao Qu, Steven Eschrich, Hidetaka Uramoto, Fumihiro Tanaka, Patrick Nasarre, Robert M Gemmill, Joëlle Roche, Harry A Drabkin, Eric B Haura
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147344 (2016)
Epithelial-mesenchymal transition (EMT) is one mechanism of acquired resistance to inhibitors of the epidermal growth factor receptor-tyrosine kinases (EGFR-TKIs) in non-small cell lung cancer (NSCLC). The precise mechanisms of EMT-related acquired r
Externí odkaz:
https://doaj.org/article/3c458785300d4584b84ebdf4b59582e9