Zobrazeno 1 - 10
of 8 706
pro vyhledávání: '"Patrick N."'
Autor:
Pinar Cakmak, Philipp Jurmeister, Iris Divé, Pia S. Zeiner, Joachim P. Steinbach, Tim R. Fenton, Karl H. Plate, Marcus Czabanka, Patrick N. Harter, Katharina J. Weber
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Giant cell (gc)-enriched glioblastoma (gcGB) represents a distinct histological variant of isocitrate dehydrogenase wild-type adult-type glioblastoma with notable enlarged mono- or multinuclear tumor cells. While some studies sugg
Externí odkaz:
https://doaj.org/article/8526f144477745d7a6ce35afef5ef37a
Autor:
Svenja Klinsing, Julia Beck, Katharina J. Weber, Kirsten Bornemann-Kolatzki, Mareike Dettki, Hans Urban, Bastian Roller, Kai U. Chow, Henning Reis, Peter J. Wild, Ekkehard Schuetz, Philipp Euskirchen, Joachim P. Steinbach, Michael W. Ronellenfitsch, Patrick N. Harter, Pia S. Zeiner
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract The gold standard for precise diagnostic classification of brain tumors requires tissue sampling, which carries relevant procedural risks. Brain biopsies often have limited sensitivity and fail to address tumor heterogeneity, because small t
Externí odkaz:
https://doaj.org/article/bb49ac9722b644f68630890aba9b3785
Autor:
Mathias M. Nilsen, Andreas S. Stordal, Rolf J. Lorentzen, Patrick N. Raanes, Kjersti S. Eikrem
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract We investigate the use of various momentum methods in combination with an ensemble approximation of gradients, for accelerated optimization. Although momentum gradient descent methods are popular in machine learning, it is unclear how they p
Externí odkaz:
https://doaj.org/article/04abd20f666f4513a1d7ead1bd06921f
Autor:
Jonathan Weller, Marcus Unterrainer, Markéta Sonderer, Sophie Katzendobler, Adrien Holzgreve, Annamaria Biczok, Patrick N. Harter, Joerg-Christian Tonn, Nathalie L. Albert, Bogdana Suchorska
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Brain tumor volumes as assessed by magnetic resonance imaging (MRI) do not always spatially overlap with biological tumor volumes (BTV) measured by [18F]Fluoroethyltyrosine positron emission tomography ([18F]FET PET). We prospectively invest
Externí odkaz:
https://doaj.org/article/fa7a1d304ca84f3e83fe9bf5f41fbe1a
Autor:
Patrick N. Wiseman, Michaela Van der Walt, Michael O’Riordan, Kieran Brosnan, Mujeeb Shaikh, David Cosgrave
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Obesity is a rapidly growing global health concern. Limited long-term success of diet, behavioural modification and medical therapy have led to the increased performance of bariatric surgery. Laparoscopic sleeve gastrectomy, which
Externí odkaz:
https://doaj.org/article/3bbb2c8bd6f4497c8729a0c2e8922da9
Autor:
Benedikt Sauer, Jan Kueckelhaus, Nadja I. Lorenz, Süleyman Bozkurt, Dorothea Schulte, Jan‐Béla Weinem, Mohaned Benzarti, Johannes Meiser, Hans Urban, Giulia Villa, Patrick N. Harter, Christian Münch, Johannes Rieger, Joachim P. Steinbach, Dieter Henrik Heiland, Michael W. Ronellenfitsch
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 11, Pp n/a-n/a (2024)
Abstract Glioblastoma, the most frequent primary malignant brain tumour in adults, is characterised by profound yet dynamic hypoxia and nutrient depletion. To sustain survival and proliferation, tumour cells are compelled to acquire metabolic plastic
Externí odkaz:
https://doaj.org/article/953fce7d5fd0419cb7f6878acc45a495
Autor:
Patrick N. Wiseman, Sarah Power, Stephen MacNally, Deirdre Nolan, Paula Corr, Gerard Curley, Caroline M. Larkin
Publikováno v:
Journal of Neuroanaesthesiology and Critical Care, Vol 11, Iss 02, Pp 100-106 (2024)
Background Delayed cerebral ischemia (DCI) is the leading cause of adverse outcome in patients who survive the initial phase of subarachnoid hemorrhage (SAH). While guidelines recommend induced hypertension as a first-line treatment for DCI, there is
Externí odkaz:
https://doaj.org/article/0de1ebfcb20e476d92bafc12031a2fe5
Autor:
Yun Lu, Hailey A. Houson, Carlos A. Gallegos, Alessandro Mascioni, Fang Jia, Argin Aivazian, Patrick N. Song, Shannon E. Lynch, Tiara S. Napier, Ameer Mansur, Benjamin M. Larimer, Suzanne E. Lapi, Ariella B. Hanker, Anna G. Sorace
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Background Immune-positron emission tomography (PET) imaging with tracers that target CD8 and granzyme B has shown promise in predicting the therapeutic response following immune checkpoint blockade (ICB) in immunologically “hot” tumors.
Externí odkaz:
https://doaj.org/article/a67333033d1f4caf9696ae27352ee60a
Autor:
Patrick N. Mwangala, Joseph Newton Guni, Paul Mwangi, Millicent Makandi, Anita Kerubo, Rachel Odhiambo, Amina Abubakar
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
BackgroundThe psychometric properties of the Primary Care PTSD Screen for DSM-5 (PC-PTSD-5) are undocumented in Kenya and sub-Saharan Africa (SSA) at large. This study aimed to evaluate the psychometric properties of the Swahili version of the tool,
Externí odkaz:
https://doaj.org/article/15521b352c344b7dbe3a5c09a62fd456
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract African swine fever virus (ASFV) is a highly contagious and fatal hemorrhagic disease of domestic pigs, which poses a major threat to the swine industry worldwide. Studies have shown that indigenous African pigs tolerate ASFV infection bette
Externí odkaz:
https://doaj.org/article/b6435eca56f249618b8a5d59f5228ab1