Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Patrick N, Reardon"'
Autor:
Kayla A Jara, Nikolaus M Loening, Patrick N Reardon, Zhen Yu, Prajna Woonnimani, Coban Brooks, Cat H Vesely, Elisar J Barbar
Publikováno v:
eLife, Vol 11 (2022)
As the only major retrograde transporter along microtubules, cytoplasmic dynein plays crucial roles in the intracellular transport of organelles and other cargoes. Central to the function of this motor protein complex is dynein intermediate chain (IC
Externí odkaz:
https://doaj.org/article/8fc3ccdb65874b4c917186036545a17d
Autor:
Douglas R. Walker, Kayla A. Jara, Amber D. Rolland, Coban Brooks, Wendy Hare, Andrew K. Swansiger, Patrick N. Reardon, James S. Prell, Elisar J. Barbar
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 404 (2023)
LC8, a ubiquitous and highly conserved hub protein, binds over 100 proteins involved in numerous cellular functions, including cell death, signaling, tumor suppression, and viral infection. LC8 binds intrinsically disordered proteins (IDPs), and alth
Externí odkaz:
https://doaj.org/article/8501563212024d60b3f2005ca59a64c0
Autor:
Kevin S. Brown, Paige Jamieson, Wenbin Wu, Ashish Vaswani, Armando Alcazar Magana, Jaewoo Choi, Luce M. Mattio, Paul Ha-Yeon Cheong, Dylan Nelson, Patrick N. Reardon, Cristobal L. Miranda, Claudia S. Maier, Jan F. Stevens
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1400 (2022)
The slow pace of discovery of bioactive natural products can be attributed to the difficulty in rapidly identifying them in complex mixtures such as plant extracts. To overcome these hurdles, we explored the utility of two machine learning techniques
Externí odkaz:
https://doaj.org/article/9399bce4f40b420c9edc91e5af41ea89
Autor:
Kristina V. Boyko, Erin A. Rosenkranz, Derrick M. Smith, Heather L. Miears, Melissa Oueld es cheikh, Micah Z. Lund, Jeffery C. Young, Patrick N. Reardon, Mark Okon, Serge L. Smirnov, John M. Antos
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
A significant number of proteins possess sizable intrinsically disordered regions (IDRs). Due to the dynamic nature of IDRs, NMR spectroscopy is often the tool of choice for characterizing these segments. However, the application of NMR to IDRs is of
Externí odkaz:
https://doaj.org/article/4b834167ff064d10b997205d67b2a00d
Autor:
Hao Geng, Changhui Xue, Janet Mendonca, Xiao-Xin Sun, Qiong Liu, Patrick N. Reardon, Yingxiao Chen, Kendrick Qian, Vivian Hua, Alice Chen, Freddy Pan, Julia Yuan, Sang Dang, Tomasz M. Beer, Mu-Shui Dai, Sushant K. Kachhap, David Z. Qian
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Prostate cancer often develops resistance to androgen receptor (AR) targeting drugs. Here, the authors show that, under conditions of hypoxia, AR inhibition via enzalutamide increases the expression of the glycolytic enzyme phosphoglucose isomerase (
Externí odkaz:
https://doaj.org/article/0252ed6647884c3d9a7e3a856e52ca42
Autor:
Yasemin Yesiltepe, Jamie R. Nuñez, Sean M. Colby, Dennis G. Thomas, Mark I. Borkum, Patrick N. Reardon, Nancy M. Washton, Thomas O. Metz, Justin G. Teeguarden, Niranjan Govind, Ryan S. Renslow
Publikováno v:
Journal of Cheminformatics, Vol 10, Iss 1, Pp 1-16 (2018)
Abstract When using nuclear magnetic resonance (NMR) to assist in chemical identification in complex samples, researchers commonly rely on databases for chemical shift spectra. However, authentic standards are typically depended upon to build librari
Externí odkaz:
https://doaj.org/article/75692281a36543aca5bac59c7ba0c124
Autor:
Liliana Cahuas, Derek J. Muensterman, Mitchell L. Kim-Fu, Patrick N. Reardon, Ivan A. Titaley, Jennifer A. Field
Publikováno v:
Environmental Science & Technology. 56:17070-17079
Paints are widely used in indoor settings yet there are no data for volatile per- and polyfluoroalkyl substances (PFAS) for paints or knowledge if paints are potentially important sources of human exposure to PFAS. Different commercial paints (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a0bcda037ef3d17a33bf983d44daf3
https://doi.org/10.1021/acs.est.2c04864
https://doi.org/10.1021/acs.est.2c04864
Autor:
Claire Lande, Sujaya Rao, Jeffrey T Morré, Gracie Galindo, Julie Kirby, Patrick N Reardon, Gerd Bobe, Jan Frederik Stevens
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218406 (2019)
Linden (Tilia spp.), a profusely flowering temperate tree that provides bees with vital pollen and nectar, has been associated with bumble bee (Bombus spp.) mortality in Europe and North America. Bee deaths have been attributed, with inadequate evide
Externí odkaz:
https://doaj.org/article/3ed7f4ad94af4a9f92c53f6c19fbd712
The nucleocapsid protein (N) of SARS-CoV-2 is essential for virus replication, genome packaging, and maturation. N is comprised of two folded domains that are separated by a highly conserved, disordered, Ser/Arg-rich linker, and flanked by disordered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6a4597ea663dca7ca0bbc015edbf21d
https://doi.org/10.1101/2023.05.26.542392
https://doi.org/10.1101/2023.05.26.542392
