Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Patrick Mokgethi"'
Autor:
Boitumelo J. L. Zuze, Botshelo T. Radibe, Wonderful T. Choga, Ontlametse T. Bareng, Natasha O. Moraka, Dorcas Maruapula, Kedumetse Seru, Patrick Mokgethi, Baitshepi Mokaleng, Nokuthula Ndlovu, Nametso Kelentse, Molly Pretorius-Holme, Roger Shapiro, Shahin Lockman, Joseph Makhema, Vlad Novitsky, Kaelo K. Seatla, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT There are limited data on the prevalence of fostemsavir (FTR) resistance-associated polymorphisms in people with HIV in Botswana. We sought to determine the prevalence of FTR resistance-associated polymorphisms in HIV-1 subtype C sequences f
Externí odkaz:
https://doaj.org/article/8a3484c8f0984aef98f28951e867c1e8
Autor:
Baitshepi Mokaleng, Wonderful Tatenda Choga, Ontlametse Thato Bareng, Dorcas Maruapula, Doreen Ditshwanelo, Nametso Kelentse, Patrick Mokgethi, Natasha Onalenna Moraka, Modisa Sekhamo Motswaledi, Leabaneng Tawe, Catherine Kegakilwe Koofhethile, Sikhulile Moyo, Matshediso Zachariah, Simani Gaseitsiwe
Publikováno v:
Vaccines, Vol 11, Iss 5, p 1000 (2023)
HIV is known to accumulate escape mutations in the gag gene in response to the immune response from cytotoxic T lymphocytes (CTLs). These mutations can occur within an individual as well as at a population level. The population of Botswana exhibits a
Externí odkaz:
https://doaj.org/article/cc5b46af2f8d4f3eb549ce98b15f493f
Autor:
Kenanao Kotokwe, Sikhulile Moyo, Melissa Zahralban-Steele, Molly Pretorius Holme, Pinkie Melamu, Catherine Kegakilwe Koofhethile, Wonderful Tatenda Choga, Terence Mohammed, Tapiwa Nkhisang, Baitshepi Mokaleng, Dorcas Maruapula, Tsotlhe Ditlhako, Ontlametse Bareng, Patrick Mokgethi, Corretah Boleo, Joseph Makhema, Shahin Lockman, Max Essex, Manon Ragonnet-Cronin, Vlad Novitsky, Simani Gaseitsiwe, PANGEA Consortium
Publikováno v:
Viruses, Vol 15, Iss 2, p 403 (2023)
It remains unknown whether the C-C motif chemokine receptor type 5 (CCR5) coreceptor is still the predominant coreceptor used by Human Immunodeficiency Virus-1 (HIV-1) in Botswana, where the HIV-1 subtype C predominates. We sought to determine HIV-1C
Externí odkaz:
https://doaj.org/article/9cefb75749aa4c4c86d4b9634b1e4947
Autor:
Phyllis J. Kanki, Simani Gaseitsiwe, Vladimir Novitsky, Roger L. Shapiro, Shahin Lockman, Charlotte A. Chang, Catherine K. Koofhethile, Kenanao P. Kotokwe, Joseph Makhema, Myron Essex, Tulio de Oliveira, Sikhulile Moyo, Selebogo Mokgweetsi, Lorato Muchoba, Patrick Mokgethi
Publikováno v:
AIDS Res Hum Retroviruses
Although antiretroviral therapy (ART) effectively suppresses HIV replication, the latent reservoir remains the barrier to HIV eradication. It remains unknown whether long-term ART impacts levels of inducible replication-competent provirus. To address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a963ab8ca90fa25254addb219d337f28
https://doi.org/10.1089/aid.2020.0097
https://doi.org/10.1089/aid.2020.0097
Autor:
Catherine K. Koofhethile, Myron Essex, Simani Gaseitsiwe, Joseph Makhema, Phyllis J. Kanki, Sikhulile Moyo, Lorato Muchoba, Roger L. Shapiro, Patrick Mokgethi, Vladimir Novitsky, Shahin Lockman, Tendani Gaolathe, Tulio de Oliveira, Selebogo Mokgweetsi, Kenanao P. Kotokwe
Publikováno v:
Medicine
Rationale: Early initiation of antiretroviral therapy (ART) leads to long-term viral suppression, reduces proviral reservoir size, and prolongs time to rebound. Since human immunodeficiency virus (HIV) is a lifelong disease, diagnostic monitoring aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36648435e0f70ec98675bd302bb03f8a
https://pubmed.ncbi.nlm.nih.gov/31764816
https://pubmed.ncbi.nlm.nih.gov/31764816