Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Patrick Matthys"'
Autor:
Jarne Beliën, Stijn Swinnen, Robbe D’hondt, Laia Verdú de Juan, Nina Dedoncker, Patrick Matthys, Jan Bauer, Celine Vens, Sinéad Moylett, Bénédicte Dubois
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Multiple sclerosis (MS) is characterized by heterogeneity in disease course and prediction of long-term outcome remains a major challenge. Here, we investigate five myeloid markers – CHIT1, CHI3L1, sTREM2, GPNMB and CCL18 – in the cerebr
Externí odkaz:
https://doaj.org/article/d13afc90e71e462b8aff607bbf1a03d9
Autor:
Emilie Pollenus, Fran Prenen, Hendrik Possemiers, Sofie Knoops, Tania Mitera, Jochen Lamote, Amber De Visscher, Leen Vandermosten, Thao-Thy Pham, Patrick Matthys, Philippe E. Van den Steen
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Conventional natural killer (cNK) cells play an important role in the innate immune response by directly killing infected and malignant cells and by producing pro- and anti-inflammatory cytokines. Studies on their role in malaria
Externí odkaz:
https://doaj.org/article/73893ddf27254417bf00664835051b95
Autor:
Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Estefania Ugarte-Berzal, Jennifer Vandooren, Erik Martens, Mieke Gouwy, Eva Ganseman, Jo Van Damme, Patrick Matthys, Jan Jeroen Vranckx, Paul Proost, Ghislain Opdenakker
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
SDF-1/CXCL12 is a unique chemotactic factor with multiple functions on various types of precursor cells, all carrying the cognate receptor CXCR4. Whereas individual biological functions of SDF-1/CXCL12 have been well documented, practical application
Externí odkaz:
https://doaj.org/article/a3beb009fdca434c94d95233677ef312
Autor:
Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Estefania Ugarte-Berzal, Erik Martens, Bert Malengier-Devlies, Jennifer Vandooren, Jan Jeroen Vranckx, Patrick Matthys, Ghislain Opdenakker
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWound healing is a complex process to restore homeostasis after injury and insufficient skin wound healing is a considerable problem in medicine. Whereas many attempts of regenerative medicine have been made for wound healing with growth
Externí odkaz:
https://doaj.org/article/9a6150249c7b408392914a097751c5d7
Autor:
Karen Yu, Luna Dillemans, Mieke Gouwy, Helena Bessa, Mieke Metzemaekers, Erik Martens, Patrick Matthys, Xavier Bossuyt, Patrick Verschueren, Carine Wouters, Lien De Somer, Paul Proost
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPeptidylarginine deiminases (PADs) mediate citrullination, an irreversible posttranslational modification that converts arginine to citrulline residues in proteins. Rheumatoid arthritis (RA) is characterized by unique autoantibodies that
Externí odkaz:
https://doaj.org/article/9ca117eb2c8840c6a6bb1c642c7ab377
Autor:
Eva Persyn, Sigrid Wahlen, Laura Kiekens, Wouter Van Loocke, Hannah Siwe, Els Van Ammel, Zenzi De Vos, Filip Van Nieuwerburgh, Patrick Matthys, Tom Taghon, Bart Vandekerckhove, Pieter Van Vlierberghe, Georges Leclercq
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cells are cytotoxic and cytokine-producing lymphocytes that play an important role in the first line of defense against malignant or virus-infected cells. A better understanding of the transcriptional regulation of human NK cell d
Externí odkaz:
https://doaj.org/article/74d32dc0a813471ba26a5d908fb198a5
Autor:
Bert Malengier-Devlies, Jessica Filtjens, Kourosh Ahmadzadeh, Bram Boeckx, Jessica Vandenhaute, Amber De Visscher, Eline Bernaerts, Tania Mitera, Cato Jacobs, Lore Vanderbeke, Pierre Van Mol, Yannick Van Herck, Greet Hermans, Philippe Meersseman, Alexander Wilmer, Mieke Gouwy, Abhishek D. Garg, Stephanie Humblet-Baron, Frederik De Smet, Kimberly Martinod, Els Wauters, Paul Proost, Carine Wouters, Georges Leclercq, Diether Lambrechts, Joost Wauters, Patrick Matthys
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
COVID-19 is characterised by a broad spectrum of clinical and pathological features. Natural killer (NK) cells play an important role in innate immune responses to viral infections. Here, we analysed the phenotype and activity of NK cells in the bloo
Externí odkaz:
https://doaj.org/article/13d4db38766a497bbdb3b0ba63a9215a
Autor:
Ji Ma, Michael Bright Yakass, Sander Jansen, Bert Malengier-Devlies, Dominique Van Looveren, Lorena Sanchez-Felipe, Thomas Vercruysse, Birgit Weynand, Mahadesh Prasad Arkalagud Javarappa, Osbourne Quaye, Patrick Matthys, Tania Roskams, Johan Neyts, Hendrik Jan Thibaut, Kai Dallmeier
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104240- (2022)
Summary: Background: The live-attenuated yellow fever vaccine YF17D holds great promise as alternative viral vector vaccine platform, showcased by our previously presented potent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine ca
Externí odkaz:
https://doaj.org/article/270dca2fe4d84600b4955f812e5c5bb0
The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency
Autor:
Sigrid Wahlen, Filip Matthijssens, Wouter Van Loocke, Sylvie Taveirne, Laura Kiekens, Eva Persyn, Els Van Ammel, Zenzi De Vos, Stijn De Munter, Patrick Matthys, Filip Van Nieuwerburgh, Tom Taghon, Bart Vandekerckhove, Pieter Van Vlierberghe, Georges Leclercq
Publikováno v:
eLife, Vol 11 (2022)
Natural killer (NK) cells are innate lymphocytes that eliminate virus-infected and cancer cells by cytotoxicity and cytokine secretion. In addition to circulating NK cells, distinct tissue-resident NK subsets have been identified in various organs. A
Externí odkaz:
https://doaj.org/article/11397126237f4caebcb161863a688e20
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Monocytes and macrophages are innate immune cells with diverse functions ranging from phagocytosis of microorganisms to forming a bridge with the adaptive immune system. A lesser-known attribute of macrophages is their ability to fuse with each other
Externí odkaz:
https://doaj.org/article/92079bd6fff84d58b6ed79f40430517f