Zobrazeno 1 - 10
of 449
pro vyhledávání: '"Patrick Masson"'
Autor:
Alia A. Diaa, Nahed El-Mahallawy, Madiha Shoeib, Flavien Mouillard, Tom Ferté, Patrick Masson, Adele Carradò
Publikováno v:
Bioactive Materials, Vol 39, Iss , Pp 479-491 (2024)
The study examines the impact of microstructure and polymethyl methacrylate (PMMA) grafting on the degradability of Zn–Mg alloys. The mechanical properties of a Zn alloy containing 0.68 wt% Mg and extruded at 200 °C are enhanced for degradable loa
Externí odkaz:
https://doaj.org/article/47c8708d70d34ea6852fe0cf0107596f
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7822 (2024)
Mining of organophosphorous (OPs)-degrading bacterial enzymes in collections of known bacterial strains and in natural biotopes are important research fields that lead to the isolation of novel OP-degrading enzymes. Then, implementation of strategies
Externí odkaz:
https://doaj.org/article/563db117794c465e9ca1ed9f78f03f27
Autor:
Zukhra Shaihutdinova, Patrick Masson
Publikováno v:
Molecules, Vol 29, Iss 10, p 2356 (2024)
The β-adrenergic drug Mirabegron, a drug initially used for the treatment of an overactive bladder, has new potential indications and is hydrolyzed by butyrylcholinesterase (BChE). This compound is one of the only arylacylamide substrates to be cata
Externí odkaz:
https://doaj.org/article/7dc1d0f195c040949a82f026b0c6220e
Publikováno v:
Molecules, Vol 29, Iss 9, p 2140 (2024)
The participation of butyrylcholinesterase (BChE) in the degradation of atropine has been recurrently addressed for more than 70 years. However, no conclusive answer has been provided for the human enzyme so far. In the present work, a steady-state k
Externí odkaz:
https://doaj.org/article/b95868e19ece41e9be7ea81c9dcfc445
Autor:
Renata R. Kazakova, Patrick Masson
Publikováno v:
Chemistry, Vol 4, Iss 4, Pp 1466-1474 (2022)
Toxicity and pharmacological activity scales of molecules, in particular toxicants, xenobiotics, drugs, nutraceuticals, etc., are described by multiples indicators, and the most popular is the median lethal dose (LD50). At the molecular level, revers
Externí odkaz:
https://doaj.org/article/f008399e01744ba09ed4b7d120bc0905
Autor:
Tatiana Pashirova, Zukhra Shaihutdinova, Dmitry Tatarinov, Milana Mansurova, Renata Kazakova, Andrei Bogdanov, Eric Chabrière, Pauline Jacquet, David Daudé, Almaz A. Akhunzianov, Regina R. Miftakhova, Patrick Masson
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15756 (2023)
Encapsulated phosphotriesterase nanoreactors show their efficacy in the prophylaxis and post-exposure treatment of poisoning by paraoxon. A new enzyme nanoreactor (E-nRs) containing an evolved multiple mutant (L72C/Y97F/Y99F/W263V/I280T) of Saccharol
Externí odkaz:
https://doaj.org/article/0afc2c26f4cd49a1ae6c47586f0638a3
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12973 (2023)
Partial reversible inhibition of enzymes, also called hyperbolic inhibition, is an uncommon mechanism of reversible inhibition, resulting from a productive enzyme–inhibitor complex. This type of inhibition can involve competitive, mixed, non-compet
Externí odkaz:
https://doaj.org/article/30c4669bd15f45609b20a87da9e54a5c
Autor:
Aliya R. Mukhametgalieva, Andrey V. Nemtarev, Viktor V. Sykaev, Tatiana N. Pashirova, Patrick Masson
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10472 (2023)
Cholinesterases (ChEs) display a non-michaelian behavior with positively charged substrates. In the steady-state rate equation, the b factor describes this behavior: if b > 1 there is substrate activation, if b < 1 there is substrate inhibition. The
Externí odkaz:
https://doaj.org/article/8e4a379e77104f7d8782d2254d90086f
Publikováno v:
Polymers, Vol 15, Iss 5, p 1265 (2023)
The thorough characterization of polymer chains grafted through a “grafting-from” process onto substrates based on the determination of number (Mn) and weight (Mw) average molar masses, as well as dispersity (Ɖ), is quite challenging. It require
Externí odkaz:
https://doaj.org/article/16f21022e7d244159508779f758b6358
Publikováno v:
Bio-Protocol, Vol 12, Iss 8 (2022)
Biotin is an essential vitamin in plants. However, characterization of biotin deficiency has been limited by embryo lethality in mutants, which can only be rescued by supplementation of biotin. Here, we describe a protocol to characterize biotin defi
Externí odkaz:
https://doaj.org/article/135b48ef551b42199c2298fcdfee0efc