Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Patrick Massae"'
Autor:
Amber Barton, Nkoyo Faal, Athumani Ramadhani, Tamsyn Derrick, Elias Mafuru, Tara Mtuy, Patrick Massae, Aiweda Malissa, Hassan Joof, Pateh Makalo, Ansumana Sillah, Anna Harte, Harry Pickering, Robin Bailey, David Cw Mabey, Matthew J Burton, Martin J Holland
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 10, p e0011689 (2023)
BackgroundTrachoma is a neglected tropical disease caused by ocular infection with Chlamydia trachomatis, where repeated infections and chronic inflammation can ultimately result in scarring, trichiasis and blindness. While scarring is thought to be
Externí odkaz:
https://doaj.org/article/e8334fc389634c4f81e791bb17b2c840
Autor:
Harry Pickering, Athumani M. Ramadhani, Patrick Massae, Elias Mafuru, Aiweda Malisa, Kelvin Mbuya, William Makupa, Tara Mtuy, Tamsyn Derrick, Joanna Houghton, Robin L. Bailey, David C. W. Mabey, Matthew J. Burton, Martin J. Holland
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
BackgroundTrachoma, caused by ocular infection with Chlamydia trachomatis, is a neglected tropical disease that can lead to blinding pathology. Current trachoma control programmes have successfully used mass drug administration (MDA) with azithromyci
Externí odkaz:
https://doaj.org/article/58280c0a15a74945a174f8cd88ea70f8
Autor:
Tamsyn R. Derrick, Natalia Sandetskaya, Harry Pickering, Andreas Kölsch, Athumani Ramadhani, Elias Mafuru, Patrick Massae, Aiweda Malisa, Tara Mtuy, Matthew J. Burton, Martin J. Holland, Dirk Kuhlmeier
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-10 (2020)
Abstract Background The clinical signs of active trachoma are often present in the absence of ocular Chlamydia trachomatis infection, particularly following mass drug administration. Treatment decisions following impact surveys and in post-control su
Externí odkaz:
https://doaj.org/article/d772da78f63b4698a7829728ee91245a
Autor:
Amy Pinsent, Anthony W. Solomon, Robin L. Bailey, Rhiannon Bid, Anaseini Cama, Deborah Dean, Brook Goodhew, Sarah E. Gwyn, Kelvin R. Jack, Ram Prasad Kandel, Mike Kama, Patrick Massae, Colin Macleod, David C. W. Mabey, Stephanie Migchelsen, Andreas Müller, Frank Sandi, Oliver Sokana, Raebwebwe Taoaba, Rabebe Tekeraoi, Diana L. Martin, Michael. T. White
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Robust surveillance methods are needed for trachoma control and recrudescence monitoring, but existing methods have limitations. Here, Pinsent et al. analyse data from nine trachoma-endemic populations and provide operational thresholds for interpret
Externí odkaz:
https://doaj.org/article/fba24dbb292444038176e451104c1f25
Autor:
Athumani M Ramadhani, Tamsyn Derrick, David Macleod, Patrick Massae, Elias Mafuru, Aiweda Malisa, Kelvin Mbuya, Chrissy H Roberts, William Makupa, Tara Mtuy, Robin L Bailey, David C W Mabey, Martin J Holland, Matthew J Burton
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007638 (2019)
BackgroundTrachoma is a progressive blinding disease initiated by infection of the conjunctiva with Chlamydia trachomatis. Repeated infections are thought to cause chronic inflammation, which drives scarring, leading to in-turning of the eyelids. The
Externí odkaz:
https://doaj.org/article/a3a429f1e6b34c3aa86348967127400b
Autor:
Athumani M Ramadhani, Tamsyn Derrick, David Macleod, Patrick Massae, Aiweda Malisa, Kelvin Mbuya, Tara Mtuy, William Makupa, Chrissy H Roberts, Robin L Bailey, David C W Mabey, Martin J Holland, Matthew J Burton
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007559 (2019)
BackgroundTrachoma, caused by Chlamydia trachomatis, remains the leading infectious cause of blindness worldwide. Persistence and progression of the resulting clinical disease appears to be an immunologically mediated process. Azithromycin, which is
Externí odkaz:
https://doaj.org/article/7f7ef0bfed4f4b97b722d746694f9a02
Autor:
Athumani M. Ramadhani, Tamsyn Derrick, David Macleod, Patrick Massae, Tara Mtuy, David Jeffries, Chrissy H. Roberts, Robin L. Bailey, David C. W. Mabey, Martin J. Holland, Matthew J. Burton
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Trachoma, caused by Chlamydia trachomatis, is the world's leading infectious cause of blindness and remains a significant public health problem. Much of trachomatous disease pathology is thought to be caused indirectly by host cellular and immune res
Externí odkaz:
https://doaj.org/article/21472837e3c84808aeb320a4518134d2
Autor:
Tamsyn Derrick, Philip J Luthert, Hodan Jama, Victor H Hu, Patrick Massae, David Essex, Martin J Holland, Matthew J Burton
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 6, p e0004752 (2016)
PURPOSE:To characterize the histological appearance and expression of pro-inflammatory mediators, growth factors, matrix metalloproteinases and biomarkers of epithelial-mesenchymal transition (EMT) in healthy control and trachomatous trichiasis (TT)
Externí odkaz:
https://doaj.org/article/3924d343844d4becbb7115cb130e100f
Autor:
Victor H Hu, Philip J Luthert, Tamsyn Derrick, James Pullin, Helen A Weiss, Patrick Massae, Tara Mtuy, William Makupa, David Essex, David C W Mabey, Robin L Bailey, Martin J Holland, Matthew J Burton
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 5, p e0004734 (2016)
INTRODUCTION:The phenotype and function of immune cells infiltrating the conjunctiva in scarring trachoma have yet to be fully characterized. We assessed tissue morphology and immunophenotype of cellular infiltrates found in trachomatous scarring com
Externí odkaz:
https://doaj.org/article/b34adb7046974f81b03395d6d95baa28
Autor:
Matthew J Burton, Saul N Rajak, Victor H Hu, Athumani Ramadhani, Esmael Habtamu, Patrick Massae, Zerihun Tadesse, Kelly Callahan, Paul M Emerson, Peng T Khaw, David Jeffries, David C W Mabey, Robin L Bailey, Helen A Weiss, Martin J Holland
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 5, p e0003763 (2015)
BACKGROUND:Trachoma causes blindness through a conjunctival scarring process initiated by ocular Chlamydia trachomatis infection; however, the rates, drivers and pathophysiological determinants are poorly understood. We investigated progressive scarr
Externí odkaz:
https://doaj.org/article/bf463914b9bd48faa36a0394311cbbdc