Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Patrick Marcinkowski"'
Autor:
Gerd Krause, Gunnar Kleinau, Catherine L. Worth, Annika Kreuchwig, Heike Biebermann, Patrick Marcinkowski, Patrick Scheerer
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
The thyroid-stimulating hormone receptor (TSHR) is a member of the glycoprotein hormone receptors, a sub-group of class A G-protein-coupled receptors (GPCRs). TSHR and its endogenous ligand thyrotropin (TSH) are of essential importance for growth and
Externí odkaz:
https://doaj.org/article/22eed666193a4118b9f2f5b2628a3854
Autor:
Ralf Schülein, Gerd Krause, Dieter Lentz, Inna Hoyer, Jens Furkert, Claudia Rutz, Franziska Witte, Sandro Mendieta, Patrick Marcinkowski, Annika Kreuchwig
Publikováno v:
Molecular Pharmacology. 96:452-462
The large TSH-bound ectodomain of the thyrotropin receptor (TSHR) activates the transmembrane domain (TMD) indirectly via an internal agonist (IA). The ectodomain/TMD interface consists of a converging helix, a Cys-Cys-bridge-linked IA, and extracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491e8649787e832fda34f9ce9a869343
https://doi.org/10.1124/mol.119.116947
https://doi.org/10.1124/mol.119.116947
Autor:
Marc Nazaré, Sebastian Sobottka, Claudia Rutz, Anja Eckstein, Han Sun, Martin Neuenschwander, Gerd Krause, Patrick Marcinkowski, Ralf Schülein, Inna Hoyer, Edgar Specker, Jens Furkert, Jens Peter von Kries, Utta Berchner-Pfannschmidt
The thyrotropin receptor (TSHR) is the target for autoimmune thyroid stimulating antibodies (TSAb) triggering hyperthyroidism. Whereas elevated thyroid hormone synthesis by the thyroid in Graves' disease can be treated by antithyroid agents, for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ddef6ce5fc66028676f0f7910c9eea6
https://www.ncbi.nlm.nih.gov/pubmed/30351237
https://www.ncbi.nlm.nih.gov/pubmed/30351237
Autor:
Gerd Krause, Patrick Marcinkowski
Publikováno v:
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 50(12)
The thyrotropin receptor (TSHR), the lutropin- (LHR), and the follicotropin receptor (FSHR) belong to glycoprotein hormone receptors (GPHR), a subgroup of the class A G-protein coupled receptors. In this review, the unique features of GPHR have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9f18851cd22a68dd0d7482d1ba78de
https://pubmed.ncbi.nlm.nih.gov/30366347
https://pubmed.ncbi.nlm.nih.gov/30366347
Autor:
Gerd Krause, Patrick Marcinkowski
Publikováno v:
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 50(12)
The thyrotropin receptor (TSHR), the lutropin- (LHR), and the follicotropin receptor (FSHR) belong to glycoprotein hormone receptors (GPHR), a subgroup of the class A G-protein coupled receptors. In this review, the unique features of GPHR have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a7b4c689e9f91ff7ab244000fc7b29
https://pubmed.ncbi.nlm.nih.gov/30453336
https://pubmed.ncbi.nlm.nih.gov/30453336
Autor:
Marc Osterland, Mathias Dahlmann, Peter M. Schlag, Pia Herrmann, Anna Okhrimenko, Ulrike Stein, Patrick Marcinkowski, Claus W. Heizmann, Janice Smith
Publikováno v:
Oncotarget
// Mathias Dahlmann 1 , Anna Okhrimenko 1 , Patrick Marcinkowski 1 , Marc Osterland 1 , Pia Herrmann 1 , Janice Smith 2 , Claus W. Heizmann 3 , Peter M. Schlag 1,4 , Ulrike Stein 1 1 Experimental and Clinical Research Center, Charite University Medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cde11b57e16458815dac1734c81f13
https://pubmed.ncbi.nlm.nih.gov/24952599
https://pubmed.ncbi.nlm.nih.gov/24952599