Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Patrick M. WOSTER"'
Autor:
Steven Holshouser, Rebecca Cafiero, Mayra Robinson, Joy Kirkpatrick, Robert A. Casero, Hyacinth I. Hyacinth, Patrick M. Woster
Publikováno v:
ACS Omega, Vol 5, Iss 24, Pp 14750-14758 (2020)
Externí odkaz:
https://doaj.org/article/a198f0ce2a5b483a957a6716c257bb64
Autor:
Amelia B. Furbish, Ahmed S. Alford, Pieter Burger, Yuri K. Peterson, Tracy Murray-Stewart, Robert A. Casero, Patrick M. Woster
Publikováno v:
Medical Sciences, Vol 10, Iss 3, p 47 (2022)
The major intracellular polyamines spermine and spermidine are abundant and ubiquitous compounds that are essential for cellular growth and development. Spermine catabolism is mediated by spermine oxidase (SMOX), a highly inducible flavin-dependent a
Externí odkaz:
https://doaj.org/article/a8cb1942ba104f0a89106e36a78159a6
Publikováno v:
Epigenetics, Vol 13, Iss 5, Pp 557-572 (2018)
Periodontal disease (PD) afflicts 46% of Americans with no effective adjunctive therapies available. While most pharmacotherapy for PD targets bacteria, the host immune response is responsible for driving tissue damage and bone loss in severe disease
Externí odkaz:
https://doaj.org/article/2388ac6f1f1c49bda1a8ba473b9271de
Autor:
Kamal El Bissati, Henry Redel, Li-Min Ting, Joseph D. Lykins, Martin J. McPhillie, Rajendra Upadhya, Patrick M. Woster, Nigel Yarlett, Kami Kim, Louis M. Weiss
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Twenty-two compounds belonging to several classes of polyamine analogs have been examined for their ability to inhibit the growth of the human malaria parasite Plasmodium falciparum in vitro and in vivo. Four lead compounds from the thiourea sub-seri
Externí odkaz:
https://doaj.org/article/ef4b5cffc7f242ea9db0685ae8654b83
Autor:
Catherine M. Mills, Thomas Z. Benton, Ivett Piña, Megan J. Francis, Leticia Reyes, Nathan G. Dolloff, Yuri K. Peterson, Patrick M. Woster
Publikováno v:
Chemical Science. 14:2168-2182
Small molecule inhibitors of CD38 promote increases in interferon gamma and stimulate natural killer cell proliferation for the treatment of neuroblastoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6347f5cf64b2fdaeea4a09a389e345dc
https://doi.org/10.1039/d2sc05749b
https://doi.org/10.1039/d2sc05749b
Autor:
Robert A. Casero, Laurence J. Marton, Patrick M. Woster, Christin L. Hanigan, Tracy Murray-Stewart
PDF file, 87K, Figure S1. Chemical structures of the natural polyamine spermine and the spermine analogues PG-11047 and BENSpm. Figure S2. Effects of treatment with PG-11047, BENSpm, and MS-275 on chromatin acetylation status. (A) Promoter region occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c20f3bd3f9285eca58802c97f76490d
https://doi.org/10.1158/1535-7163.22497417.v1
https://doi.org/10.1158/1535-7163.22497417.v1
Autor:
Robert A. Casero, Laurence J. Marton, Patrick M. Woster, Christin L. Hanigan, Tracy Murray-Stewart
The treatment of specific tumor cell lines with poly- and oligoamine analogs results in a superinduction of polyamine catabolism that is associated with cytotoxicity; however, other tumor cells show resistance to analog treatment. Recent data indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba0267cf5856ca7baf2d5cedb3aa1cf
https://doi.org/10.1158/1535-7163.c.6535608.v1
https://doi.org/10.1158/1535-7163.c.6535608.v1
Autor:
Robert A. Casero, Patrick M. Woster, Richard J. Jones, Brandy Perkins, Laurence J. Marton, Stephen B. Baylin, Yu Wu, Tracy Murray Stewart, Yi Huang
CCR Translation for the Article from Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::520d9423f442a140ed86d07d2cb0d7ec
https://doi.org/10.1158/1078-0432.22439985
https://doi.org/10.1158/1078-0432.22439985
Autor:
Robert A. Casero, Patrick M. Woster, Richard J. Jones, Brandy Perkins, Laurence J. Marton, Stephen B. Baylin, Yu Wu, Tracy Murray Stewart, Yi Huang
Supplementary Data from Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126b6a7be80754b24afc2a245b2fe76f
https://doi.org/10.1158/1078-0432.22439982
https://doi.org/10.1158/1078-0432.22439982
Autor:
Robert A. Casero, Patrick M. Woster, Richard J. Jones, Brandy Perkins, Laurence J. Marton, Stephen B. Baylin, Yu Wu, Tracy Murray Stewart, Yi Huang
Purpose: Abnormal DNA CpG island hypermethylation and transcriptionally repressive histone modifications are associated with the aberrant silencing of tumor suppressor genes. Lysine methylation is a dynamic, enzymatically controlled process. Lysine-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d612b28d495f07f1aae76c07a4f3ec
https://doi.org/10.1158/1078-0432.c.6517362.v1
https://doi.org/10.1158/1078-0432.c.6517362.v1