Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Patrick M. Tate"'
Publikováno v:
Cell Reports, Vol 28, Iss 10, Pp 2620-2633.e4 (2019)
Summary: Common antivirals include nucleoside or nucleotide analogs with base prodrugs. The antiviral ribavirin, a US Food and Drug Administration (FDA)-approved nucleoside antimetabolite, halts guanine production, mutagenizes viral genomes, and acti
Externí odkaz:
https://doaj.org/article/89835e0e25b04c37a4a98b26dcc20ad0
Publikováno v:
Viruses, Vol 11, Iss 5, p 403 (2019)
Polyamines are small positively-charged molecules abundant in eukaryotic cells that are crucial to RNA virus replication. In eukaryotic cells, polyamines facilitate processes such as transcription, translation, and DNA replication, and viruses simila
Externí odkaz:
https://doaj.org/article/1f2853ace6f44a5aa62349ed09f3f8c7
Publikováno v:
Cell Reports, Vol 28, Iss 10, Pp 2620-2633.e4 (2019)
Summary: Common antivirals include nucleoside or nucleotide analogs with base prodrugs. The antiviral ribavirin, a US Food and Drug Administration (FDA)-approved nucleoside antimetabolite, halts guanine production, mutagenizes viral genomes, and acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355614a3ece210b0c7ea330e4751cf7f
http://www.sciencedirect.com/science/article/pii/S2211124719310150
http://www.sciencedirect.com/science/article/pii/S2211124719310150
Publikováno v:
Journal of Virology. 93
Polyamines are small polycationic molecules with flexible carbon chains that are found in all eukaryotic cells. Polyamines are involved in the regulation of many host processes and have been shown to be implicated in viral replication. Depletion of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de33214e3031f2bdd45d6d769c328ce
https://doi.org/10.1128/jvi.01054-19
https://doi.org/10.1128/jvi.01054-19
Autor:
Grant M Hawkins, Courtney N. Dial, Zachary J. Sandler, Bryan C. Mounce, Marion L Graham, David J. Rademacher, Vincent Mastrodomenico, Patrick M. Tate, Thomas M Kicmal, Jeremy J. Esin
Publikováno v:
Journal of Virology. 93
Several host and viral processes contribute to forming infectious virions. Polyamines are small host molecules that play diverse roles in viral replication. We previously demonstrated that polyamines are crucial for RNA viruses; however, the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006bb1c7e4786294b8557c87a87c9205
https://doi.org/10.1128/jvi.00530-19
https://doi.org/10.1128/jvi.00530-19
Publikováno v:
Viruses
Volume 11
Issue 5
Viruses, Vol 11, Iss 5, p 403 (2019)
Volume 11
Issue 5
Viruses, Vol 11, Iss 5, p 403 (2019)
Polyamines are small positively-charged molecules abundant in eukaryotic cells that are crucial to RNA virus replication. In eukaryotic cells, polyamines facilitate processes such as transcription, translation, and DNA replication, and viruses simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce778b24480bcf7b6ba217216eedd695
Autor:
Da-Neng Wang, Zheng Liu, Patrick M. Tate, Victor J. Torres, Akiko Koide, David B. Sauer, Shohei Koide, Douglas N. Brawley, Jinmei Song, Xuhui Zheng, Nathaniel J. Traaseth
Publikováno v:
Biophysical Journal. 120:174a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03d486c951c9228cf92b4d36e9722f58
https://doi.org/10.1016/j.bpj.2020.11.1224
https://doi.org/10.1016/j.bpj.2020.11.1224
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(19)
Eudistomin U is a member of the β-carboline class of heterocyclic amine-containing molecules that are capable of binding to DNA. The structure of eudistomin U is unique since it contains an indole ring at the 1-position of the pyridine ring. While s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272d22a10ab513846b2414167ba9c9fd
https://pubmed.ncbi.nlm.nih.gov/27567367
https://pubmed.ncbi.nlm.nih.gov/27567367
Publikováno v:
The FASEB Journal. 29
Natural products have been the leading source of potential drug leads and comprise approximately a third of the drugs on the market. β-carbolines are a class of naturally occurring, tricyclic aromatic indole alkaloids that have been used to probe th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::548e97d30bee098f2f48110a40a7e7a9
https://doi.org/10.1096/fasebj.29.1_supplement.721.45
https://doi.org/10.1096/fasebj.29.1_supplement.721.45