Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Patrick M. Perrigue"'
1
Akademický článek
Cellular uptake and retention studies of silica nanoparticles utilizing senescent fibroblasts
Autor: Patrick M. Perrigue, Agata Henschke, Bartosz F. Grześkowiak, Łucja Przysiecka, Kaja Jaskot, Angelika Mielcarek, Emerson Coy, Sergio E. Moya
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Understanding the interplay between nanoparticles (NPs) and cells is essential to designing more efficient nanomedicines. Previous research has shown the role of the cell cycle having impact on the efficiency of cellular uptake and accumulat
Externí odkaz: https://doaj.org/article/585bfb6575a946f6bca91385fe6ec135
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2
Akademický článek
Degradation of Drug Delivery Nanocarriers and Payload Release: A Review of Physical Methods for Tracing Nanocarrier Biological Fate
Autor: Patrick M. Perrigue, Richard A. Murray, Angelika Mielcarek, Agata Henschke, Sergio E. Moya
Publikováno v: Pharmaceutics, Vol 13, Iss 6, p 770 (2021)
Nanoformulations offer multiple advantages over conventional drug delivery, enhancing solubility, biocompatibility, and bioavailability of drugs. Nanocarriers can be engineered with targeting ligands for reaching specific tissue or cells, thus reduci
Externí odkaz: https://doaj.org/article/7f829a17b37d448ba63184ad7525525b
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3
Akademický článek
L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells
Autor: Zhongqi Li, Diana Oganesyan, Rachael Mooney, Xianfang Rong, Matthew J. Christensen, David Shahmanyan, Patrick M. Perrigue, Joseph Benetatos, Lusine Tsaturyan, Soraya Aramburo, Alexander J. Annala, Yang Lu, Joseph Najbauer, Xiwei Wu, Michael E. Barish, David L. Brody, Karen S. Aboody, Margarita Gutova
Publikováno v: Stem Cell Reports, Vol 7, Iss 3, Pp 483-495 (2016)
Pre-clinical studies indicate that neural stem cells (NSCs) can limit or reverse CNS damage through direct cell replacement, promotion of regeneration, or delivery of therapeutic agents. Immortalized NSC lines are in growing demand due to the inheren
Externí odkaz: https://doaj.org/article/d24fb8dca87e44b6928ea1b9798e1120
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4
Akademický článek
Total DNA Methylation Changes Reflect Random Oxidative DNA Damage in Gliomas
Autor: Anna-Maria Barciszewska, Małgorzata Giel-Pietraszuk, Patrick M. Perrigue, Mirosława Naskręt-Barciszewska
Publikováno v: Cells, Vol 8, Iss 9, p 1065 (2019)
DNA modifications can be used to monitor pathological processes. We have previously shown that estimating the amount of the main DNA epigenetic mark, 5-methylcytosine (m5C), is an efficient and reliable way to diagnose brain tumors, hypertension, and
Externí odkaz: https://doaj.org/article/04563210a1194a79bb94caab09c21743
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8
Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts
Autor: Magdalena Rakoczy, Małgorzata Giel-Pietraszuk, Kamila Pawlicka, Marek Figlerowicz, Jan Barciszewski, Agnieszka Belter, Patrick M. Perrigue, Mirosława Z. Naskręt-Barciszewska
Publikováno v: Cancers
Cancers, Vol 12, Iss 1745, p 1745 (2020)
Volume 12
Issue 7
Cellular senescence is a tumor-suppressive mechanism blocking cell proliferation in response to stress. However, recent evidence suggests that senescent tumor cells can re-enter the cell cycle to become cancer stem cells, leading to relapse after can
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be672301c8b2ec33789129585fd3757
http://europepmc.org/articles/PMC7409320
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9
Total DNA Methylation Changes Reflect Random Oxidative DNA Damage in Gliomas
Autor: Małgorzata Giel-Pietraszuk, Mirosława Z. Naskręt-Barciszewska, Anna-Maria Barciszewska, Patrick M. Perrigue
Publikováno v: Cells, Vol 8, Iss 9, p 1065 (2019)
Cells
Volume 8
Issue 9
DNA modifications can be used to monitor pathological processes. We have previously shown that estimating the amount of the main DNA epigenetic mark, 5-methylcytosine (m5C), is an efficient and reliable way to diagnose brain tumors, hypertension, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c458ef73783326afd7b53b35dc6224
https://www.mdpi.com/2073-4409/8/9/1065
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10
L- MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells
Autor: Alexander J. Annala, Xiwei Wu, Joseph Benetatos, Zhongqi Li, Rachael Mooney, Joseph Najbauer, Karen S. Aboody, Yang Lu, Diana Oganesyan, Soraya Aramburo, David L. Brody, David Shahmanyan, Michael E. Barish, Xianfang Rong, Patrick M. Perrigue, Lusine Tsaturyan, Margarita Gutova, Matthew J. Christensen
Publikováno v: Stem Cell Reports
Stem Cell Reports, Vol 7, Iss 3, Pp 483-495 (2016)
Summary Pre-clinical studies indicate that neural stem cells (NSCs) can limit or reverse CNS damage through direct cell replacement, promotion of regeneration, or delivery of therapeutic agents. Immortalized NSC lines are in growing demand due to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f332b32aa102e9ef7b4d9bc26d6ce8e
https://doi.org/10.1016/j.stemcr.2016.07.013
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