Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Patrick M. Navolanic"'
Autor:
Roberto Di Marco, Massimiliano Anzaldi, Salvatore Santo Signorelli, Massimo Libra, Graziella Malaponte, Sergio Neri, Valerio Fiore, Patrick M. Navolanic, Katia Mangano, Cinzia Quattrocchi
Previous research analyzed the level of plasma inflammatory markers in patients with coronary disease, but very few studies have evaluated these markers in patients with peripheral arterial disease (PAD). The objective of this study was to investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460543add22a0f182f5da138953024d0
http://hdl.handle.net/11695/57807
http://hdl.handle.net/11695/57807
Autor:
Umberto Tirelli, Antonino Carbone, Massimo Libra, Daniela Gasparotto, Michele Spina, Patrick M. Navolanic, Annunziata Gloghini
Publikováno v:
Modern Pathology. 19:299-306
Lymphoma with prominent spindle cell features, the so-called spindle cell lymphoma, is an unusual morphological variant of diffuse large B-cell lymphoma. Five new cases of spindle cell lymphoma have been analyzed by a multiparameter approach in order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f33bc7b1b6f1801ab150b406a14a79
https://doi.org/10.1038/modpathol.3800540
https://doi.org/10.1038/modpathol.3800540
Autor:
Salvatore Santo Signorelli, Massimo Libra, Jerry Polesel, Ylenia Bevelacqua, Valentina Bevelacqua, Graziella Malaponte, Maria Clorinda Mazzarino, Patrick M. Navolanic, Franca Stivala, Renato Talamini
Publikováno v:
Journal of Clinical Pathology. 59:211-215
Aims: To determine whether the G(−174)C interleukin 6 (IL-6) polymorphism influences the development of peripheral arterial disease (PAD) in individuals with type 2 diabetes. This was investigated by comparing the distribution of G(−174)C genotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91935432653b40a3a4d01e990d689ece
https://doi.org/10.1136/jcp.2004.025452
https://doi.org/10.1136/jcp.2004.025452
Autor:
John T. Lee, Richard A. Franklin, Massimo Libra, Jeffrey L. Salisbury, A B D'Assoro, Franca Stivala, Maria Clorinda Mazzarino, Linda S. Steelman, Patrick M. Navolanic, Fumin Chang, Fred E. Bertrand, Steven L. Abrams, James A. McCubrey, David M. Terrian
Publikováno v:
Advances in Enzyme Regulation. 46:249-279
The Ras/Raf/MEK/ERK and PI3K/PTEN/AKT signaling cascades play critical roles in the transmission of signals from growth factor receptors to regulate gene expression and prevent apoptosis. Components of these pathways are mutated or aberrantly express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3714e2177f6624492b604a55f36facf6
https://doi.org/10.1016/j.advenzreg.2006.01.004
https://doi.org/10.1016/j.advenzreg.2006.01.004
Autor:
John G. Shelton, William L. Blalock, Richard A. Franklin, James A. McCubrey, Patrick M. Navolanic, Fumin Chang, John T. Lee, Linda S. Steelman
Publikováno v:
Leukemia. 17:1263-1293
The Ras/Raf/Mitogen-activated protein kinase/ERK kinase (MEK)/extracellular-signal-regulated kinase (ERK) cascade couples signals from cell surface receptors to transcription factors, which regulate gene expression. Depending upon the stimulus and ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07e62176b73620a38392ab31ebc4c21
https://doi.org/10.1038/sj.leu.2402945
https://doi.org/10.1038/sj.leu.2402945
Autor:
John T. Lee, Linda S. Steelman, Patrick M. Navolanic, James A. McCubrey, William L. Blalock, John G. Shelton, Richard A. Franklin, Martyn K. White, Martin McMahon, P W Moye, Amer M. Mirza
Publikováno v:
Leukemia. 17:1058-1067
The Raf/MEK/ERK kinase cascade plays a critical role in transducing growth signals from activated cell surface receptors. Using DeltaMEK1:ER, a conditionally active form of MEK1 which responds to either beta-estradiol or the estrogen receptor antagon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3948fec2bc551f0c106b2b49900dd58c
https://doi.org/10.1038/sj.leu.2402925
https://doi.org/10.1038/sj.leu.2402925
Autor:
Richard A. Franklin, Linda S. Steelman, John T. Lee, Patrick M. Navolanic, John G. Shelton, William L. Blalock, Fumin Chang, James A. McCubrey
Publikováno v:
Leukemia. 17:590-603
The PI3K/Akt signal transduction cascade has been investigated extensively for its roles in oncogenic transformation. Initial studies implicated both PI3K and Akt in prevention of apoptosis. However, more recent evidence has also associated this path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5deb23d3a2d9d2e049b79fda5d38e6c9
https://doi.org/10.1038/sj.leu.2402824
https://doi.org/10.1038/sj.leu.2402824
Autor:
Michael R. Bishop, John P. Leonard, Jeha Sc, J A McCubrey, Stewart Goldman, Richard A. Larson, Mitchell S. Cairo, Pearce Te, Ching-Hon Pui, Carl Shanholtz, Patrick M. Navolanic
Publikováno v:
Leukemia. 17:499-514
Renal precipitation of uric acid associated with tumor lysis syndrome (TLS) is a major complication in the management of leukemia, lymphoma, and other drug-sensitive cancers. Management of hyperuricema has historically consisted of administration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21da0917d795edbe12385ec3c467c9a4
https://doi.org/10.1038/sj.leu.2402847
https://doi.org/10.1038/sj.leu.2402847
Autor:
Massimo Libra, Grazia Malaponte, Lidia Proietti, James A. McCubrey, Salvatore Travali, Pietro Gangemi, Patrick M. Navolanic, Franca Stivala, Bibiana Bruni, Valentina Bevelacqua, Maria Clorinda Mazzarino
Publikováno v:
Scopus-Elsevier
Mutation of BRAF has been proposed to contribute to melanoma development. However, it remains unclear whether or not BRAF mutation is associated with any particular stage of melanoma progression. Tumor biopsy specimens from patients with melanoma wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b445c1681618601537748c7f9581244e
https://doi.org/10.4161/cc.4.10.2026
https://doi.org/10.4161/cc.4.10.2026
Autor:
Linda S, Steelman, Patrick M, Navolanic, Richard A, Franklin, Antonio, Bonati, Massimo, Libra, Franca, Stivala, Alberto M, Martelli, James A, McCubrey
Publikováno v:
Molecular medicine reports. 1(2)
Breast cancer ranks as the second most common cause of cancer death among women in the United States. Anticancer agents are an important component of breast cancer therapy. Drugs frequently used to treat breast cancer include methotrexate, 5-fluorour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::294be969592a06cb292857e10af5943b
https://pubmed.ncbi.nlm.nih.gov/21479390
https://pubmed.ncbi.nlm.nih.gov/21479390