Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Patrick M. Durkin"'
Autor:
Erhan Deniz, Luis Valiño-Borau, Jan G. Löffler, Katharina B. Eberl, Adnan Gulzar, Steffen Wolf, Patrick M. Durkin, Robert Kaml, Nediljko Budisa, Gerhard Stock, Jens Bredenbeck
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Vibrational energy transfer (VET) is essential for protein function as it is responsible for efficient energy dissipation in reaction sites and is linked to pathways of allosteric communication. Here authors equipped a tryptophan zipper with a VET in
Externí odkaz:
https://doaj.org/article/61744375dbee47668eb67fc4afc0bb9f
Autor:
Ian Derrick, Timothy Gallagher, Claire A. Haseler, Patrick M Durkin, Christoph Hirschhäuser, Pietro Magrone
Publikováno v:
The Journal of Organic Chemistry. 75:3766-3774
The scope and limitations of the intramolecular 1,6-addition of an enolate to a 2-pyridone moiety, a reaction that has found application in the synthesis of the lupin alkaloids, have been probed. This nucleophilic addition process has been shown to b
Publikováno v:
Biopolymers. 104(5)
Tryptophan has been taken as the basic scaffold for a chromophore whose indole residue can be further functionalized by the introduction of endocyclic nitrogen atoms or by N-methylation. When compared with exocyclic modifications, modifying tryptopha
Publikováno v:
Synlett. 2010:2789-2791
The application of a lactam enolate-pyridone addition sequence, originally developed for cytisine, has been applied successfully to generate the first examples of 4-halocytisines. Variation of the lactam component provides cyfusine and 4-fluorocyfusi