Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Patrick Münzer"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Formation of Neutrophil Extracellular Traps (NETosis), accompanied by the release of extracellular decondensed chromatin and pro-inflammatory as well as pro-thrombotic factors, is a pivotal element in the development and progression of thrombo-occlus
Externí odkaz:
https://doaj.org/article/98e922d278c949e29b62cd121fe9b379
Autor:
Anne-Katrin Rohlfing, Kyra Kolb, Manuel Sigle, Melanie Ziegler, Alexander Bild, Patrick Münzer, Jessica Sudmann, Valerie Dicenta, Tobias Harm, Mailin-Christin Manke, Sascha Geue, Marcel Kremser, Madhumita Chatterjee, Chunguang Liang, Hendrik von Eysmondt, Thomas Dandekar, David Heinzmann, Manina Günter, Saskia von Ungern-Sternberg, Manuela Büttcher, Tatsiana Castor, Stine Mencl, Friederike Langhauser, Katharina Sies, Diyaa Ashour, Mustafa Caglar Beker, Michael Lämmerhofer, Stella E. Autenrieth, Tilman E. Schäffer, Stefan Laufer, Paulina Szklanna, Patricia Maguire, Matthias Heikenwalder, Karin Anne Lydia Müller, Dirk M. Hermann, Ertugrul Kilic, Ralf Stumm, Gustavo Ramos, Christoph Kleinschnitz, Oliver Borst, Harald F. Langer, Dominik Rath, Meinrad Gawaz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
ACKR3 is a critical regulator of platelet-mediated thrombosis and organ injury following ischemia/reperfusion. Platelet ACKR3 surface expression is independently associated with all-cause mortality in patients with cardiovascular diseases.
Externí odkaz:
https://doaj.org/article/bff45f142b4844968bc8a69ceae8231a
Autor:
Patrick Münzer, Roberto Negro, Shoichi Fukui, Lucas di Meglio, Karen Aymonnier, Long Chu, Deya Cherpokova, Sarah Gutch, Nicoletta Sorvillo, Lai Shi, Venkat Giri Magupalli, Alexander N. R. Weber, Rüdiger E. Scharf, Clare M. Waterman, Hao Wu, Denisa D. Wagner
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophil extracellular trap formation (NETosis) and the NLR family pyrin domain containing 3 (NLRP3) inflammasome assembly are associated with a similar spectrum of human disorders. While NETosis is known to be regulated by peptidylarginine deimina
Externí odkaz:
https://doaj.org/article/2d05e129ea374b9f8cb826c28431c42d
Autor:
Patrick Münzer, Oliver Borst
Publikováno v:
Cells, Vol 11, Iss 4, p 619 (2022)
Thrombo-occlusive diseases such as myocardial infarction, ischemic stroke and deep vein thrombosis with subsequent pulmonary embolism still represent a major health burden worldwide. Besides the cells of the vasculature or other hematopoietic cells,
Externí odkaz:
https://doaj.org/article/51c3b15b20534ddfa2387ccf59790ae8
Autor:
Patricia B. Maguire, Martin E. Parsons, Paulina B. Szklanna, Monika Zdanyte, Patrick Münzer, Madhumita Chatterjee, Kieran Wynne, Dominik Rath, Shane P. Comer, Melanie Hayden, Fionnuala Ní Áinle, Meinrad Gawaz
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Upon activation, platelets release a host of soluble and vesicular signals, collectively termed the “platelet releasate” (PR). The contents of this PR play a significant role in haemostasis, inflammation, and pathologic sequelae. Despite this, pr
Externí odkaz:
https://doaj.org/article/54d7a47a1c8a471197c7d69f0ca6437b
Autor:
Oliver Borst, Patrick Münzer, Nada Alnaggar, Sascha Geue, Roland Tegtmeyer, Dominik Rath, Michal Droppa, Peter Seizer, Stefan Heitmeier, Johan W.M. Heemskerk, Lisa K. Jennings, Robert F. Storey, Dominick J. Angiolillo, Bianca Rocca, Henri Spronk, Hugo Ten Cate, Meinrad Gawaz, Tobias Geisler
Publikováno v:
Blood Advances, Vol 2, Iss 6, Pp 715-730 (2018)
Abstract: Very low–dose (VLD) factor Xa (FXa) inhibition, in combination with acetylsalicylic acid (ASA) and clopidogrel, is associated with improved outcomes in patients with acute coronary syndrome (ACS) with a tolerable bleeding risk profile. To
Externí odkaz:
https://doaj.org/article/d9e3884a70ea426791e0641813794a24
Autor:
Yuetao Zhou, Madhuri S. Salker, Britta Walker, Patrick Münzer, Oliver Borst, Meinrad Gawaz, Erich Gulbins, Yogesh Singh, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 3, Pp 985-995 (2016)
Background/Aims: Regulatory T cell (Treg) is required for the maintenance of tolerance to various tissue antigens and to protect the host from autoimmune disorders. However, Treg may, indirectly, support cancer progression and bacterial infections. T
Externí odkaz:
https://doaj.org/article/31258b40ceb24bafbea70115c2653aec
Autor:
Oliver Borst, Britta Walker, Patrick Münzer, Antonella Russo, Evi Schmid, Caterina Faggio, Boris Bigalke, Stefan Laufer, Meinrad Gawaz, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 31, Iss 6, Pp 914-924 (2013)
Background/Aims: Platelets are critically important for primary haemostasis and the major players in thrombotic vascular occlusion. Platelets are activated by agonists, such as thrombin and collagen-related peptide as well as second-wave mediators in
Externí odkaz:
https://doaj.org/article/1d16ea74728c485d95b22c3d81d0dd12
Autor:
Syeda T. Towhid, Eva-Maria Schmidt, Alexander Tolios, Patrick Münzer, Evi Schmid, Oliver Borst, Meinrad Gawaz, Evi Stegmann, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 31, Iss 1, Pp 102-112 (2013)
Background/Aims: Side effects of vancomycin, a widely used antibiotic, include thrombocytopenia. The vancomycin-induced thrombocytopenia has been attributed to immune reactions. At least in theory, thrombocytopenia could result in part from the trigg
Externí odkaz:
https://doaj.org/article/a73c7097c6144e94a9ff9fd2a61f0edb
Autor:
Nina S Gowert, Lili Donner, Madhumita Chatterjee, Yvonne S Eisele, Seyda T Towhid, Patrick Münzer, Britta Walker, Isabella Ogorek, Oliver Borst, Maria Grandoch, Martin Schaller, Jens W Fischer, Meinrad Gawaz, Sascha Weggen, Florian Lang, Mathias Jucker, Margitta Elvers
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90523 (2014)
Alzheimer's disease (AD) is characterized by neurotoxic amyloid-ß plaque formation in brain parenchyma and cerebral blood vessels known as cerebral amyloid angiopathy (CAA). Besides CAA, AD is strongly related to vascular diseases such as stroke and
Externí odkaz:
https://doaj.org/article/28262559de414f24ab89ec45d0d6c575