Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Patrick M, Carry"'
Autor:
Patrick M. Carry, Lauren A. Vanderlinden, Randi K. Johnson, Teresa Buckner, Andrea K. Steck, Katerina Kechris, Ivana V. Yang, Tasha E. Fingerlin, Oliver Fiehn, Marian Rewers, Jill M. Norris
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundType 1 diabetes (T1D) is preceded by a heterogenous pre-clinical phase, islet autoimmunity (IA). We aimed to identify pre vs. post-IA seroconversion (SV) changes in DNAm that differed across three IA progression phenotypes, those who lose a
Externí odkaz:
https://doaj.org/article/13d1cee8ffcf44c0a63da89f47ca487c
Autor:
Patrick M. Carry, Tim Vigers, Lauren A. Vanderlinden, Carson Keeter, Fran Dong, Teresa Buckner, Elizabeth Litkowski, Ivana Yang, Jill M. Norris, Katerina Kechris
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background We developed a novel approach to minimize batch effects when assigning samples to batches. Our algorithm selects a batch allocation, among all possible ways of assigning samples to batches, that minimizes differences in average pr
Externí odkaz:
https://doaj.org/article/f5f3161d1212472ba1fb4cc3ce02231b
Autor:
Teresa Buckner, Randi K. Johnson, Lauren A. Vanderlinden, Patrick M. Carry, Alex Romero, Suna Onengut-Gumuscu, Wei-Min Chen, Soojeong Kim, Oliver Fiehn, Brigitte I. Frohnert, Tessa Crume, Wei Perng, Katerina Kechris, Marian Rewers, Jill M. Norris
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
BackgroundOxylipins are inflammatory biomarkers derived from omega-3 and-6 fatty acids implicated in inflammatory diseases but have not been studied in a genome-wide association study (GWAS). The aim of this study was to identify genetic loci associa
Externí odkaz:
https://doaj.org/article/1fe4b1d6ea3a4185b725567210cde705
Autor:
Sulafa Elhassan, Fran Dong, Teresa Buckner, Randi K. Johnson, Jennifer A. Seifert, Patrick M. Carry, Lauren Vanderlinden, Kathleen Waugh, Marian Rewers, Jill M. Norris
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundStudies of the role of iron in the risk of type 1 diabetes (T1D) have been inconsistent. Given that iron generates reactive oxygen radicals, which can lead to oxidative damage and apoptosis in the beta cells of the pancreas, we examined whe
Externí odkaz:
https://doaj.org/article/30d76eca792b41168fc0dd1cbe9b638b
Autor:
Lauren A. Vanderlinden, Randi K. Johnson, Patrick M. Carry, Fran Dong, Dawn L. DeMeo, Ivana V. Yang, Jill M. Norris, Katerina Kechris
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract Objective Illumina BeadChip arrays are commonly used to generate DNA methylation data for large epidemiological studies. Updates in technology over time create challenges for data harmonization within and between studies, many of which obtai
Externí odkaz:
https://doaj.org/article/70d7935c93f24ff6b5f49921e5cd5dfa
Autor:
Minami K. Yamamura, Patrick M. Carry, Romie F. Gibly, Kaley Holmes, Brandon Ogilvie, Alicia Phillips, Gaia Georgopoulos, Nancy Hadley Miller, Karin A. Payne
Publikováno v:
Journal of the American Academy of Orthopaedic Surgeons. 31:e507-e515
Autor:
Christopher J. Brazell, Patrick M. Carry, Kaley S. Holmes, Reba L. Salton, Nancy Hadley-Miller, Gaia Georgopoulos
Publikováno v:
Orthopedics. :1-7
Large-scale studies examining fracture trends and epidemiological data are lacking. The purpose of this study was to evaluate the incidence of fractures presenting to US emergency departments using the National Electronic Injury Surveillance System.
Autor:
Margaret S, Murphy-Zane, Patrick M, Carry, Reba L, Salton, Nancy, Hadley Miller, Kaley, Holmes, Tyler, Freeman, Matthew, Belton, Brian, Kohuth, Deborah, Burke, Gaia, Georgopoulos
Publikováno v:
Journal of Pediatric Orthopaedics. 43:e138-e143
This analysis examined how the application of the American Academy of Orthopedic Surgeons appropriate use criteria (AUC) for developmental dysplasia of the hip in infants would change treatment patterns and outcomes for Graf IIA hips at a single quat
Autor:
Tim Vigers, Lauren A. Vanderlinden, Randi K. Johnson, Patrick M. Carry, Ivana Yang, Brian C. DeFelice, Alexander M. Kaizer, Laura Pyle, Marian Rewers, Oliver Fiehn, Jill M. Norris, Katerina Kechris
Publikováno v:
Metabolites, Vol 11, Iss 8, p 542 (2021)
Environmental factors including viruses, diet, and the metabolome have been linked with the appearance of islet autoimmunity (IA) that precedes development of type 1 diabetes (T1D). We measured global DNA methylation (DNAm) and untargeted metabolomic
Externí odkaz:
https://doaj.org/article/714dbdf695d241429a1a4ba14acd0040
Autor:
Patrick M Carry, Victoria R Duke, Christopher J Brazell, Nicholas Stence, Melissa Scholes, Dominique L Rousie, Nancy Hadley Miller
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232417 (2020)
PurposeAdolescent idiopathic scoliosis (AIS) is a three-dimensional spinal structural deformity that occurs in otherwise normal individuals. Although curve progression and severity vary amongst individuals, AIS can lead to significant cosmetic and fu
Externí odkaz:
https://doaj.org/article/59e5d0e07ab1444c87348beb009f3a95