In vivo and in silico evaluation of a new nitric oxide donor, S,S′ -dinitrosobucillamine

Autor: François Dupuis, Caroline Perrin-Sarrado, Alessandro Genoni, Pierre Leroy, Philippe Giummelly, Ariane Boudier, Valérie Salgues, Benjamin Meyer, Isabelle Lartaud, Igor Clarot, Manuel F. Ruiz-López, Patrick Limiñana, Mostafa Kouach, Marie-Lynda Bouressam

Publikováno v: Nitric Oxide: Biology and Chemistry
Nitric Oxide: Biology and Chemistry, Elsevier, 2017, 71, pp.32-43. ⟨10.1016/j.niox.2017.10.004⟩
Nitric Oxide: Biology and Chemistry, 2017, 71, pp.32-43. ⟨10.1016/j.niox.2017.10.004⟩

International audience; Purpose: In a previous work, we have synthetized a new dinitrosothiol, i.e. S,S′-dinitrosobucillamine BUC(NO)2 combining S-nitroso-N-acetylpenicillamine (SNAP) and S-nitroso-N-acetylcysteine (NACNO) in its structure. When ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e486b3faf94c09ab2f12953ca08e7c
https://hal.univ-lorraine.fr/hal-01665352/file/Bouressam_et_al_Nitric_Oxide_2017.pdf

Captopril improves cerebrovascular structure and function in old hypertensive rats

Autor: Jean-Marc Chillon, François Dupuis, Jeffrey Atkinson, Patrick Limiñana

Publikováno v: British Journal of Pharmacology. 144:349-356

1 We examined the effects of an angiotensin-converting enzyme inhibitor (ACEI), captopril, on cerebral arterioles in young and old spontaneously hypertensive rats (SHR). 2 Animals were anesthetized with sodium pentobarbitone (60 mg kg−1 day−1). W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::930ea4813b24654697e2dc31ee14e4fb
https://doi.org/10.1038/sj.bjp.0706001

High salt intake abolishes AT2-mediated vasodilation of pial arterioles in rats

Autor: Faten Merhi-Soussi, François Dupuis, Isabelle Lartaud, Christine Capdeville-Atkinson, Yiu Wa Kwan, Caroline Perrin-Sarrado, Patrick Limiñana, Sébastien Foulquier, Katy Maguin Gaté, Jeffrey Atkinson

Publikováno v: Journal of Hypertension
Journal of Hypertension, Lippincott, Williams & Wilkins, 2011, 29 (7), pp.1392-1399. ⟨10.1097/HJH.0b013e328347050e⟩

International audience; Angiotensin II (Ang II) induces constriction (AT(1)) and dilation (AT(2) receptors) of cerebral arterioles. High sodium intake induces changes in receptors expression and loss of AT(2)-mediated vasodilation in extracerebral ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b532a2158052224b3021ca51ebbb5d6
https://hal.univ-lorraine.fr/hal-01646675

Impact of treatment with melatonin on cerebral circulation in old rats

Autor: François, Dupuis, Olivier, Régrigny, Jeffrey, Atkinson, Patrick, Limiñana, Philippe, Delagrange, Elizabeth, Scalbert, Jean-Marc, Chillon

Publikováno v: British journal of pharmacology. 141(3)

Melatonin deprival in young rats induces alterations in cerebral arteriolar wall similar to those observed during aging: atrophy and a decrease in distensibility. In this study, we examined the effects of melatonin treatment on cerebral arteriolar st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6cfaca14af444e34c23afada35f7fe5a
https://pubmed.ncbi.nlm.nih.gov/14718260

7.2 IN WHICH EXTENT GAMMA-GLUTAMYLTRANSFERASE CONTRIBUTES TO THE VASORELAXANT EFFECT OF S-NITROSOGLUTATHIONE?

Autor: Caroline Perrin-Sarrado, Patrick Limiñana, Alfonso Pompella, Pierre Leroy, Isabelle Lartaud, Ariane Boudier, C. Gaucher-di Stasio, Fatima Dahboul, K. Maguin Gate

Publikováno v: Artery Research, Vol 5, Iss 4 (2011)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8ecc5888b55db2878cc1294d95a676
https://doi.org/10.1016/j.artres.2011.10.232