Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Patrick Lebok"'
Autor:
Simon Kind, Carolina Palacios Castillo, Ria Schlichter, Natalia Gorbokon, Maximilian Lennartz, Lisa S. Hornsteiner, Sebastian Dwertmann Rico, Viktor Reiswich, Florian Viehweger, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Franziska Büscheck, Till S. Clauditz, Christoph Fraune, Andrea Hinsch, Till Krech, Patrick Lebok, Stefan Steurer, Eike Burandt, Sarah Minner, Andreas H. Marx, Ronald Simon, Waldemar Wilczak, Guido Sauter, Anne Menz, Frank Jacobsen
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and thus plays a pivotal role in maintaining skin homeostasis. In cancer, KLK7 overexpression was
Externí odkaz:
https://doaj.org/article/5ac61efaf1d649688eb409482a34a7c5
Autor:
Nina Schraps, Jacob Constantin Port, Anne Menz, Florian Viehweger, Seyma Büyücek, David Dum, Ria Schlichter, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Martina Kluth, Claudia Hube‐Magg, Katharina Möller, Viktor Reiswich, Andreas M. Luebke, Patrick Lebok, Sören Weidemann, Guido Sauter, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Andreas H. Marx, Ronald Simon, Stefan Steurer, Baris Mercanoglu, Nathaniel Melling, Thilo Hackert, Eike Burandt, Natalia Gorbokon, Sarah Minner, Till Krech, Florian Lutz
Publikováno v:
Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)
ABSTRACT Backround Anterior gradient 2 (AGR2) is a resident endoplasmic reticulum (ER) protein with a vital role in embryonal development, mucus maturation, tissue regeneration, and wound healing. Methods To determine the prevalence and clinical sign
Externí odkaz:
https://doaj.org/article/63147fc510d546f48524d9789dc18496
Autor:
Florian Viehweger, Carola Böcker, Sören Weidemann, Morton Freytag, Anne Menz, Franziska Büscheck, Andreas M. Luebke, Devita Putri, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Maximilian Lennartz, Florian Lutz, Viktor Reiswich, Doris Höflmayer, Christoph Fraune, Katharina Möller, Christian Bernreuther, Patrick Lebok, Guido Sauter, Stefan Steurer, David Dum, Andreas H. Marx, Ronald Simon, Till Krech, Till S. Clauditz, Frank Jacobsen, Natalia Gorbokon, Eike Burandt, Sarah Minner, Simon Kind
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background Prostein (P501S), also termed solute carrier family 45 member 3 (SLC45A3) is an androgen regulated protein which is preferentially expressed in prostate epithelial cells. Because of its frequent expression in prostate cancer, pros
Externí odkaz:
https://doaj.org/article/1ce52e7787bb496aabfb9873d8fef92f
Autor:
Florian Lutz, Soo-Young Han, Seyma Büyücek, Katharina Möller, Florian Viehweger, Ria Schlichter, Anne Menz, Andreas M. Luebke, Ahmed Abdulwahab Bawahab, Viktor Reiswich, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Sören Weidemann, Maximilian Lennartz, David Dum, Christian Bernreuther, Patrick Lebok, Guido Sauter, Andreas H. Marx, Ronald Simon, Till Krech, Christoph Fraune, Natalia Gorbokon, Eike Burandt, Sarah Minner, Stefan Steurer, Till S. Clauditz, Frank Jacobsen
Publikováno v:
Diagnostics, Vol 14, Iss 19, p 2157 (2024)
Background/Objectives: Trefoil factor 1 (TFF1) plays a role in the mucus barrier. Methods: To evaluate the prevalence of TFF1 expression in cancer, a tissue microarray containing 18,878 samples from 149 tumor types and 608 samples of 76 normal tissue
Externí odkaz:
https://doaj.org/article/98d38a2aa4434efc97a21e0fd50a656d
Autor:
Maximilian Lennartz, Henrietta Csomós, Viktoria Chirico, Sören Weidemann, Natalia Gorbokon, Anne Menz, Franziska Büscheck, Claudia Hube-Magg, Doris Höflmayer, Christian Bernreuther, Niclas C. Blessin, Patrick Lebok, Guido Sauter, Stefan Steurer, Eike Burandt, David Dum, Till Krech, Ronald Simon, Sarah Minner, Frank Jacobsen, Till S. Clauditz, Andreas M. Luebke, Abdul Khalid Siraj, Fouad Al-Dayel, Khawla S. Al-Kuraya, Andrea Hinsch
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Cadherin-16 (CDH16) plays a role in the embryonal development in kidney and thyroid. Downregulation of CDH16 RNA was found in papillary carcinomas of the thyroid. To determine the expression of CDH16 in tumors and to assess the diagnostic ut
Externí odkaz:
https://doaj.org/article/bbfd9ebdf3b84c049d5620f1b25266ec
Autor:
Anne Menz, Nora Lony, Maximilian Lennartz, Sebastian Dwertmann Rico, Ria Schlichter, Simon Kind, Viktor Reiswich, Florian Viehweger, David Dum, Andreas M. Luebke, Martina Kluth, Natalia Gorbokon, Claudia Hube-Magg, Christian Bernreuther, Ronald Simon, Till S. Clauditz, Guido Sauter, Andrea Hinsch, Frank Jacobsen, Andreas H. Marx, Stefan Steurer, Sarah Minner, Eike Burandt, Till Krech, Patrick Lebok, Sören Weidemann
Publikováno v:
Diagnostics, Vol 14, Iss 10, p 1044 (2024)
EpCAM is expressed in many epithelial tumors and is used for the distinction of malignant mesotheliomas from adenocarcinomas and as a surrogate pan-epithelial marker. A tissue microarray containing 14,832 samples from 120 different tumor categories w
Externí odkaz:
https://doaj.org/article/37a7dfa58a674ff98acd50533d86ce0c
Autor:
Florian Viehweger, Jennifer Hoop, Lisa-Marie Tinger, Christian Bernreuther, Franziska Büscheck, Till S. Clauditz, Andrea Hinsch, Frank Jacobsen, Andreas M. Luebke, Stefan Steurer, Claudia Hube-Magg, Martina Kluth, Andreas H. Marx, Till Krech, Patrick Lebok, Christoph Fraune, Eike Burandt, Guido Sauter, Ronald Simon, Sarah Minner
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 957 (2024)
Androgen receptor (AR) is a transcription factor expressed in various normal tissues and is a therapeutic target for prostate and possibly other cancers. A TMA containing 18,234 samples from 141 different tumor types/subtypes and 608 samples of 76 di
Externí odkaz:
https://doaj.org/article/67466c86e8b94945acb66492eacdd01e
Autor:
Tim Mandelkow, Elena Bady, Magalie C. J. Lurati, Jonas B. Raedler, Jan H. Müller, Zhihao Huang, Eik Vettorazzi, Maximilian Lennartz, Till S. Clauditz, Patrick Lebok, Lisa Steinhilper, Linn Woelber, Guido Sauter, Enikö Berkes, Simon Bühler, Peter Paluchowski, Uwe Heilenkötter, Volkmar Müller, Barbara Schmalfeldt, Albert von der Assen, Frank Jacobsen, Till Krech, Rainer H. Krech, Ronald Simon, Christian Bernreuther, Stefan Steurer, Eike Burandt, Niclas C. Blessin
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3175 (2023)
Prognostic markers in routine clinical management of breast cancer are often assessed using RNA-based multi-gene panels that depend on fluctuating tumor purity. Multiplex fluorescence immunohistochemistry (mfIHC) holds the potential for an improved r
Externí odkaz:
https://doaj.org/article/36bff2cc5d55475d8196e9f7dd6cc9c6
Autor:
Laura Sophie Tribian, Maximilian Lennartz, Doris Höflmayer, Noémi de Wispelaere, Sebastian Dwertmann Rico, Clara von Bargen, Simon Kind, Viktor Reiswich, Florian Viehweger, Florian Lutz, Veit Bertram, Christoph Fraune, Natalia Gorbokon, Sören Weidemann, Claudia Hube-Magg, Anne Menz, Ria Uhlig, Till Krech, Andrea Hinsch, Eike Burandt, Guido Sauter, Ronald Simon, Martina Kluth, Stefan Steurer, Andreas H. Marx, Patrick Lebok, David Dum, Sarah Minner, Frank Jacobsen, Till S. Clauditz, Christian Bernreuther
Publikováno v:
Diagnostics, Vol 13, Iss 20, p 3242 (2023)
Prostate-specific acid phosphatase (PSAP) is a marker for prostate cancer. To assess the specificity and prognostic impact of PSAP, 14,137 samples from 127 different tumor (sub)types, 17,747 prostate cancers, and 76 different normal tissue types were
Externí odkaz:
https://doaj.org/article/260e28f917f945e4b0a035b10b40ec43
Autor:
Ria Uhlig, Nina Bröker, Sören Weidemann, Natalia Gorbokon, Anne Menz, Franziska Büscheck, Andreas M Luebke, Devita Putri, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Maximilian Lennartz, Viktor Reiswich, Doris Höflmayer, Christoph Fraune, Katharina Möller, Christian Bernreuther, Patrick Lebok, Guido Sauter, Sarah Minner, Stefan Steurer, Eike Burandt, Rainer Krech, David Dum, Andreas Marx, Ronald Simon, Till Krech, Till S Clauditz, Frank Jacobsen
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287528 (2023)
Chymotrypsin-like elastase family member 3B (CELA3B, elastase-3B) is a pancreatic enzyme with digestive function in the intestine. Since RNA analyses of normal tissues suggest that CELA3B expression is limited to the pancreas, the potential diagnosti
Externí odkaz:
https://doaj.org/article/899c288372aa4b03ab5c490b5f24035d