Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Patrick Lau"'
Autor:
Matteo Scorcelletti, Jochen Zange, Jonas Böcker, Wolfram Sies, Patrick Lau, Uwe Mittag, Neil D. Reeves, Alex Ireland, Jörn Rittweger
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Features of lower limb bone geometry are associated with movement kinematics and clinical outcomes including fractures and osteoarthritis. Therefore, it is important to identify their determinants. Lower limb geometry changes dramatical
Externí odkaz:
https://doaj.org/article/ca9ba95fa6884434b13f0b433ada2c3f
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 342 (2022)
The dissociation of bone formation and resorption is an important physiological process during spaceflight. It also occurs during local skeletal unloading or immobilization, such as in people with neuromuscular disorders or those who are on bed rest.
Externí odkaz:
https://doaj.org/article/fd4c8c088495425f86d3c82603b7fb78
Autor:
Zhen-Yong Keck, Brian G Pierce, Patrick Lau, Janine Lu, Yong Wang, Alexander Underwood, Rowena A Bull, Jannick Prentoe, Rodrigo Velázquez-Moctezuma, Melanie R Walker, Fabio Luciani, Johnathan D Guest, Catherine Fauvelle, Thomas F Baumert, Jens Bukh, Andrew R Lloyd, Steven K H Foung
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007772 (2019)
Cumulative evidence supports a role for neutralizing antibodies contributing to spontaneous viral clearance during acute hepatitis C virus (HCV) infection. Information on the timing and specificity of the B cell response associated with clearance is
Externí odkaz:
https://doaj.org/article/02ca33a0a5d144a7a284f9c9f72f99b4
Autor:
Zewen Kelvin Tuong, Rebecca Fitzsimmons, Shu-Ching Mary Wang, Tae Gyu Oh, Patrick Lau, Frederik Steyn, Gethin Thomas, George E.O. Muscat
Publikováno v:
EBioMedicine, Vol 11, Iss C, Pp 101-117 (2016)
RORα is a member of the nuclear receptor (NR) superfamily and analysis of the (global) RORα-deficient mouse model revealed this NR has a role in glycemic control and fat deposition. Therefore, we generated an adipose-specific RORα ‘gain of funct
Externí odkaz:
https://doaj.org/article/9a268d51f1f44530b3a43e3c6d5584ac
Autor:
Zewen Kelvin Tuong, Patrick Lau, Ximing Du, Nicholas D Condon, Joel M Goode, Tae Gyu Oh, Jeremy C Yeo, George E O Muscat, Jennifer L Stow
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147179 (2016)
Nuclear hormone receptors have important roles in the regulation of metabolic and inflammatory pathways. The retinoid-related orphan receptor alpha (Rorα)-deficient staggerer (sg/sg) mice display several phenotypes indicative of aberrant lipid metab
Externí odkaz:
https://doaj.org/article/61f2313aad8344a498cd7c54cd093eba
Autor:
Zhen-yong Keck, Allan G N Angus, Wenyan Wang, Patrick Lau, Yong Wang, Derek Gatherer, Arvind H Patel, Steven K H Foung
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004297 (2014)
A challenge for hepatitis C virus (HCV) vaccine development is to define epitopes that are able to elicit protective antibodies against this highly diverse virus. The E2 glycoprotein region located at residues 412-423 is conserved and antibodies to 4
Externí odkaz:
https://doaj.org/article/a9bb5eb1ccdf44dc99201ffff062dbad
Autor:
Gregory Cheng, Rino Alvani Gani, Ji Dong Jia, Diana A. Payawal, Guo Feng Chen, Khin Maung Win, Simone I. Strasser, Zhen Wen Liu, Hasmik Ghazinian, Saeed Hamid, Tony Mok, Tanwandee Tawesak, Jer Ming Chang, Ann-Lii Cheng, Shiv Kumar Sarin, Jin Lin Hou, Rosmawaiti Mohamed, Pierce K. H. Chow, Grace Lai-Hung Wong, Masashi Mizokami, Patrick Lau, Woon Leung Ng, George Lau, Teerha Piratvisuth, Oidov Baatarkhuu, A. Kadir Dokmeci, Ming-Lung Yu, Alexander J. Thompson, Masao Omata, Joong-Won Park
Publikováno v:
Hepatology International
Background & Aim Hepatitis B reactivation related to the use of immunosuppressive therapy remains a major cause of liver-related morbidity and mortality in hepatitis B endemic Asia-Pacific region. This clinical practice guidelines aim to assist clini
Publikováno v:
Current Urology.
Publikováno v:
ACS Biomaterials Science & Engineering. 7:2615-2626
The combination of macro- and microporosity is a potent manner of enhancing osteogenic potential, but the biological events leading to this increase in osteogenesis are not well understood. In this study, we investigated the effect of a dual pore siz
Autor:
Alma Balestrazzi, Cinzia Calvio, Anca Macovei, Andrea Pagano, Patrick Laux, Hassane Moutahir, Loїc Rajjou, Eleni Tani, Dimosthenis Chachalis, Christos Katsis, Lamiae Ghaouti, Said Gmouh, Sanaa Majid, Amine Elleuch, Moez Hanin, Bassem Khemakhem, Hanen El Abed, Joao Nunes, Susana Araújo, Aziz Benhamrouche, Mohand Bersi
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
In developing countries, orphan legumes stand at the forefront in the struggle against climate change. Their high nutrient value is crucial in malnutrition and chronic diseases prevention. However, as the ‘orphan’ definition suggests, their seed
Externí odkaz:
https://doaj.org/article/ce2836bdb56f41e390a183ba0bf08583