Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Patrick Laprise"'
Autor:
Sara L. Banerjee, Frédéric Lessard, François J.M. Chartier, Kévin Jacquet, Ana I. Osornio-Hernandez, Valentine Teyssier, Karim Ghani, Noémie Lavoie, Josée N. Lavoie, Manuel Caruso, Patrick Laprise, Sabine Elowe, Jean-Philippe Lambert, Nicolas Bisson
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111031- (2022)
Summary: EPH receptors (EPHRs) constitute the largest family among receptor tyrosine kinases in humans. They are mainly involved in short-range cell-cell communication events that regulate cell adhesion, migration, and boundary formation. However, th
Externí odkaz:
https://doaj.org/article/8fd2c903558b408894f403b0c0bd57f6
Autor:
Cornelia Biehler, Katheryn E Rothenberg, Alexandra Jette, Helori-Mael Gaude, Rodrigo Fernandez-Gonzalez, Patrick Laprise
Publikováno v:
eLife, Vol 10 (2021)
The Drosophila polarity protein Crumbs is essential for the establishment and growth of the apical domain in epithelial cells. The protein Yurt limits the ability of Crumbs to promote apical membrane growth, thereby defining proper apical/lateral mem
Externí odkaz:
https://doaj.org/article/41dc7f1f3a404852bf2f5ed8b65a4f6f
Autor:
Cornélia Biehler, Li-Ting Wang, Myriam Sévigny, Alexandra Jetté, Clémence L Gamblin, Rachel Catterall, Elise Houssin, Luke McCaffrey, Patrick Laprise
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008674 (2020)
Epithelial cell polarity defects support cancer progression. It is thus crucial to decipher the functional interactions within the polarity protein network. Here we show that Drosophila Girdin and its human ortholog (GIRDIN) sustain the function of c
Externí odkaz:
https://doaj.org/article/c6d446d3491048b99a113c4d201ddbaf
Publikováno v:
Biology Open, Vol 5, Iss 1, Pp 49-54 (2016)
The morphometric parameters of epithelial tubes are critical to the physiology and homeostasis of most organs. In addition, many human diseases are associated with tube-size defects. Here, we show that Rac1 limits epithelial tube elongation in the de
Externí odkaz:
https://doaj.org/article/3addb4a9991f4689979aa067b3e9acd6
Autor:
Cristina Gareau, Elise Houssin, David Martel, Laetitia Coudert, Samia Mellaoui, Marc-Etienne Huot, Patrick Laprise, Rachid Mazroui
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55342 (2013)
The RNA-binding protein Fragile X Mental Retardation (FMRP) is an evolutionarily conserved protein that is particularly abundant in the brain due to its high expression in neurons. FMRP deficiency causes fragile X mental retardation syndrome. In neur
Externí odkaz:
https://doaj.org/article/6a8fac1e64a14c7ca08d66bf0dd8c934
Autor:
Rodrigo Fernandez-Gonzalez, Patrick Laprise, Alexandra Jetté, Cornélia Biehler, Katheryn E. Rothenberg, Helori-Mael Gaude
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
The Drosophila polarity protein Crumbs is essential for the establishment and growth of the apical domain in epithelial cells. The protein Yurt limits the ability of Crumbs to promote apical membrane growth, thereby defining proper apical/lateral mem
Autor:
Josée N. Lavoie, Ana I. Osornio-Hernandez, Nicolas Bisson, Jean-Philippe Lambert, Sabine Elowe, Kévin Jacquet, Frédéric Lessard, Sara L. Banerjee, Patrick Laprise, Noémie Lavoie
SUMMARYThe EPH family is the largest among receptor tyrosine kinases (RTKs) in humans. In contrast to other RTKs, EPH receptors (EPHRs) cognate ligands, ephrins, are tethered to the cell surface. This results in EPHR-ephrin signaling being mainly inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bb8a3eb31896985b704b825eb08df08
https://doi.org/10.1101/2020.09.06.285270
https://doi.org/10.1101/2020.09.06.285270
Autor:
Jonathan Bergeman, Darren E. Richard, Marie-Chloé Boulanger, Francois Bordeleau, Claire Dziengelewski, Herman Lambert, Kévin Jacquet, Marc-Étienne Huot, Margit Fuchs, Alexia Caillier, Patrick Laprise, Marc-Antoine Rodrigue, Josée N. Lavoie
Publikováno v:
The Journal of Cell Biology
The plasticity of cancer cells depends on numerous factors that distinguish them from normal cells. Proteins with a tumor cell–selective killing activity offer powerful tools to uncover fundamental differences. Dziengelewski et al. show that one su
Autor:
Jean-Philippe Lambert, Frédéric Lessard, Sabine Elowe, Kévin Jacquet, Sara L. Banerjee, Josée N. Lavoie, Patrick Laprise, Noémie Lavoie, Nicolas Bisson
Publikováno v:
SSRN Electronic Journal.
The EPH family is the largest among receptor tyrosine kinases (RTKs) in humans. In contrast to other RTKs, EPH receptors (EPHRs) cognate ligands, ephrins, are tethered to the cell surface. This results in EPHR-ephrin signaling being mainly involved i