Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Patrick L Wagner"'
Autor:
Sven Perner, Patrick L Wagner, Francesca Demichelis, Rohit Mehra, Christopher J LaFargue, Benjamin J Moss, Stefanie Arbogast, Alex Soltermann, Walter Weder, Thomas J Giordano, David G Beer, David S Rickman, Arul M Chinnaiyan, Holger Moch, Mark A Rubin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 3, Pp 298-302 (2008)
A recurrent gene fusion between EML4 and ALK in 6.7% of non-small cell lung cancers (NSCLCs) and NKX2-1 (TTF1, TITF1) high-level amplifications in 12% of adenocarcinomas of the lung were independently reported recently. Because the EML4-ALK fusion wa
Externí odkaz:
https://doaj.org/article/fa6a25e867ee4e21909b1c06f037b237
Autor:
Neda Dadgar, Christopher Sherry, Jenna Zimmerman, Hyun Park, Catherine Lewis, Albert Donnenberg, Ali H. Zaidi, Yong Fan, Kunhong Xiao, David Bartlett, Vera Donnenberg, Patrick L. Wagner
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Peritoneal carcinomatosis (PC) is a complex manifestation of abdominal cancers, with a poor prognosis and limited treatment options. Recent work identifying high concentrations of the cytokine interleukin-6 (IL-6) and its soluble receptor (s
Externí odkaz:
https://doaj.org/article/a71ee4cc59e64df78edf01e2021607ca
Autor:
Bibek Aryal, Zhadyra Bizhanova, Edward A. Joseph, Yue Yin, Patrick L. Wagner, Emily Dalton, William A. LaFramboise, David L. Bartlett, Casey J. Allen
Publikováno v:
Cancers, Vol 16, Iss 4, p 760 (2024)
Advancing cancer treatment relies on the rapid translation of new scientific discoveries to patient care. To facilitate this, an oncology biobank and data repository program, also referred to as the “Moonshot” program, was launched in 2021 within
Externí odkaz:
https://doaj.org/article/8e50e6f080e4426fa4b677fd8419f5c0
Autor:
Catherine R. Lewis, Neda Dadgar, Samuel A. Yellin, Vera S. Donnenberg, Albert D. Donnenberg, David L. Bartlett, Casey J. Allen, Patrick L. Wagner
Publikováno v:
Cancers, Vol 15, Iss 20, p 5107 (2023)
Peritoneal carcinomatosis originating from gastric/gastroesophageal junction cancer (GC-PC) occurs in a defined subset of gastric cancer patients with unique clinical, pathologic, molecular and immunologic characteristics that create significant obst
Externí odkaz:
https://doaj.org/article/6d4074c5f4844ba0834a436e16564ea5
Publikováno v:
Cancers, Vol 15, Iss 18, p 4426 (2023)
Immunotherapy has shown promise as a treatment option for gastroesophageal cancer, but its effectiveness is limited in many patients due to the immunosuppressive tumor microenvironment (TME) commonly found in gastrointestinal tumors. This paper explo
Externí odkaz:
https://doaj.org/article/260cdbf3f5a0402d9887641ee4948df5
Autor:
Vera S. Donnenberg, Patrick L. Wagner, James D. Luketich, David L. Bartlett, Albert D. Donnenberg
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Metastasis to the pleural and peritoneal cavities is a common terminal pathway for a wide variety of cancers. This article explores how these unique environments both promote aggressive tumor behavior and suppresses anti-tumor immunity, and ways in w
Externí odkaz:
https://doaj.org/article/680442810c3f447b9389d36923b3aaeb
Autor:
Ali H. Zaidi, Muhammad Yogi Pratama, Ashten N. Omstead, Anastasia Gorbonova, Rubab Mansoor, Rachael Melton-Kreft, Blair A. Jobe, Patrick L. Wagner, Ronan J. Kelly, Ajay Goel
Publikováno v:
British Journal of Cancer. 127:2016-2024
Emerging evidence indicates the potential clinical significance of specific microbial signatures as diagnostic and prognostic biomarkers, in multiple cancers. However, to date, no studies have systematically interrogated circulating metagenome profil
Autor:
Casey J Allen, Nathan Bloom, Michael Rothka, Pavan Rao, Patrick L Wagner, David L Bartlett, Katie Farah, Sricharan Chalikonda
Publikováno v:
Journal of the American College of Surgeons.
Autor:
Ashten N Omstead, Michael Paskewicz, Anastasia Gorbunova, Ping Zheng, Madison S Salvitti, Rubab Mansoor, Payton Reed, Sydne Ballengee, Patrick L Wagner, Blair A Jobe, Ronan J Kelly, Ali H Zaidi
Publikováno v:
Carcinogenesis. 43:842-850
Esophageal adenocarcinoma (EAC) is a leading cause of cancer deaths. Pexidartinib, a multi-gene tyrosine kinase inhibitor, through targeting colony-stimulating factor 1 (CSF-1) receptor (CSF-1R), down modulates macrophage-mediated pro-survival tumor
Autor:
Pavan K Rao, Samantha Falls, Stacey Shipley, Katie Farah, Patrick L Wagner, David L Bartlett, Sricharan Chalikonda, Casey J Allen
Publikováno v:
Journal of the American College of Surgeons. 235:S43-S43