Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Patrick L Wagner"'
Autor:
Patrick L. Wagner, Jianwu Xie, Devin C. Flaherty, Hyun Park, Chelsea Knotts, Justine Debelius, Curtis Tilves, Neda Dadgar, Kunhong Xiao, Ali H. Zaidi, Louis Gil Acevedo, William LaFramboise, Ni Zhao, Cynthia Sears, Noel Mueller
Publikováno v:
Frontiers in Gastroenterology, Vol 3 (2024)
BackgroundIntra-tumoral lymphocytes hold prognostic and predictive significance in colorectal cancer (CRC). The internationally validated Immunoscore™ predicts CRC survival risk by averaging percentile scores of tumor-associated CD3+ and CD8+ cell
Externí odkaz:
https://doaj.org/article/48defe3cde3b4de29ccb665df38a6fe5
Autor:
Sven Perner, Patrick L Wagner, Francesca Demichelis, Rohit Mehra, Christopher J LaFargue, Benjamin J Moss, Stefanie Arbogast, Alex Soltermann, Walter Weder, Thomas J Giordano, David G Beer, David S Rickman, Arul M Chinnaiyan, Holger Moch, Mark A Rubin
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 3, Pp 298-302 (2008)
A recurrent gene fusion between EML4 and ALK in 6.7% of non-small cell lung cancers (NSCLCs) and NKX2-1 (TTF1, TITF1) high-level amplifications in 12% of adenocarcinomas of the lung were independently reported recently. Because the EML4-ALK fusion wa
Externí odkaz:
https://doaj.org/article/fa6a25e867ee4e21909b1c06f037b237
Autor:
Neda Dadgar, Christopher Sherry, Jenna Zimmerman, Hyun Park, Catherine Lewis, Albert Donnenberg, Ali H. Zaidi, Yong Fan, Kunhong Xiao, David Bartlett, Vera Donnenberg, Patrick L. Wagner
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Peritoneal carcinomatosis (PC) is a complex manifestation of abdominal cancers, with a poor prognosis and limited treatment options. Recent work identifying high concentrations of the cytokine interleukin-6 (IL-6) and its soluble receptor (s
Externí odkaz:
https://doaj.org/article/a71ee4cc59e64df78edf01e2021607ca
Autor:
Vera S. Donnenberg, Patrick L. Wagner, James D. Luketich, David L. Bartlett, Albert D. Donnenberg
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Metastasis to the pleural and peritoneal cavities is a common terminal pathway for a wide variety of cancers. This article explores how these unique environments both promote aggressive tumor behavior and suppresses anti-tumor immunity, and ways in w
Externí odkaz:
https://doaj.org/article/680442810c3f447b9389d36923b3aaeb
Autor:
Ali H. Zaidi, Muhammad Yogi Pratama, Ashten N. Omstead, Anastasia Gorbonova, Rubab Mansoor, Rachael Melton-Kreft, Blair A. Jobe, Patrick L. Wagner, Ronan J. Kelly, Ajay Goel
Publikováno v:
British Journal of Cancer. 127:2016-2024
Emerging evidence indicates the potential clinical significance of specific microbial signatures as diagnostic and prognostic biomarkers, in multiple cancers. However, to date, no studies have systematically interrogated circulating metagenome profil
Autor:
Casey J Allen, Nathan Bloom, Michael Rothka, Pavan Rao, Patrick L Wagner, David L Bartlett, Katie Farah, Sricharan Chalikonda
Publikováno v:
Journal of the American College of Surgeons.
Autor:
Ashten N Omstead, Michael Paskewicz, Anastasia Gorbunova, Ping Zheng, Madison S Salvitti, Rubab Mansoor, Payton Reed, Sydne Ballengee, Patrick L Wagner, Blair A Jobe, Ronan J Kelly, Ali H Zaidi
Publikováno v:
Carcinogenesis. 43:842-850
Esophageal adenocarcinoma (EAC) is a leading cause of cancer deaths. Pexidartinib, a multi-gene tyrosine kinase inhibitor, through targeting colony-stimulating factor 1 (CSF-1) receptor (CSF-1R), down modulates macrophage-mediated pro-survival tumor
Autor:
Pavan K Rao, Samantha Falls, Stacey Shipley, Katie Farah, Patrick L Wagner, David L Bartlett, Sricharan Chalikonda, Casey J Allen
Publikováno v:
Journal of the American College of Surgeons. 235:S43-S43
Publikováno v:
The Bacteriophages.
Externí odkaz:
https://doi.org/10.1093/oso/9780195168778.003.0047
Autor:
Lekshmi Ramalingam, David L. Bartlett, Amer H. Zureikat, Matthew P. Holtzman, Patrick L. Wagner, Herbert J. Zeh, James F. Pingpank, Brian A. Boone, Haroon A. Choudry, Heather Jones, Steven A. Ahrendt
Publikováno v:
Annals of Surgical Oncology. 22:588-595
Cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC) are used to treat peritoneal carcinomatosis from a variety of primary tumor sites. Little is known about the in vivo effects of CRS and HIPEC. We examined tumor and non-neopl