Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Patrick L, Purdon"'
Autor:
Carol L. Wilkinson, Lisa D. Yankowitz, Jerry Y. Chao, Rodrigo Gutiérrez, Jeff L. Rhoades, Shlomo Shinnar, Patrick L. Purdon, Charles A. Nelson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The development of neural circuits has long-lasting effects on brain function, yet our understanding of early circuit development in humans remains limited. Here, periodic EEG power features and aperiodic components were examined from longit
Externí odkaz:
https://doaj.org/article/447f823164c14852af3b7d2736b21f52
Publikováno v:
eLife, Vol 13 (2024)
Modern neurophysiological recordings are performed using multichannel sensor arrays that are able to record activity in an increasingly high number of channels numbering in the 100s to 1000s. Often, underlying lower-dimensional patterns of activity a
Externí odkaz:
https://doaj.org/article/96496d8ec2fb4dcda5b815636741baeb
Autor:
Ran Liu, Rodrigo Gutiérrez, Rory V. Mather, Tom A. D. Stone, Laura A. Santa Cruz Mercado, Kishore Bharadwaj, Jasmine Johnson, Proloy Das, Gustavo Balanza, Ekenedilichukwu Uwanaka, Justin Sydloski, Andrew Chen, Mackenzie Hagood, Edward A. Bittner, Patrick L. Purdon
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Preoperative knowledge of expected postoperative pain can help guide perioperative pain management and focus interventions on patients with the greatest risk of acute pain. However, current methods for predicting postoperative pain require p
Externí odkaz:
https://doaj.org/article/94e6d1ef1f4344a1b466232724891eda
Autor:
Emily P. Stephen, Gladia C. Hotan, Eric T. Pierce, P. Grace Harrell, John L. Walsh, Emery N. Brown, Patrick L. Purdon
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/df6e6c3fb57f44648973bd7ffcfb4867
Autor:
Fangyun Tian, Laura D. Lewis, David W. Zhou, Gustavo A. Balanza, Angelique C. Paulk, Rina Zelmann, Noam Peled, Daniel Soper, Laura A. Santa Cruz Mercado, Robert A. Peterfreund, Linda S. Aglio, Emad N. Eskandar, G. Rees Cosgrove, Ziv M. Williams, R. Mark Richardson, Emery N. Brown, Oluwaseun Akeju, Sydney S. Cash, Patrick L. Purdon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
The neural mechanisms underpinning ketamine’s dissociative and antidepressant effects remain poorly understood. Here, the authors analyzed ketamine-induced brain dynamics with intracranial recordings in humans and found that ketamine engages differ
Externí odkaz:
https://doaj.org/article/da8d61cabb16496a94d360fce79c2d24
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1011395 (2023)
Linear parametric state-space models are a ubiquitous tool for analyzing neural time series data, providing a way to characterize the underlying brain dynamics with much greater statistical efficiency than non-parametric data analysis approaches. How
Externí odkaz:
https://doaj.org/article/802b3a36ebc24ad5b073ea73d5194830
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Phase amplitude coupling (PAC) is thought to play a fundamental role in the dynamic coordination of brain circuits and systems. There are however growing concerns that existing methods for PAC analysis are prone to error and misinterpretatio
Externí odkaz:
https://doaj.org/article/645648b8eea54003be90129526348145
Autor:
Susanne Koch, Jose I. Egaña, Antonello Penna, Beverley A. Orser, Patrick L. Purdon, Rodrigo Gutiérrez
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/94a251de88df4f5992707737b838b383
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 7, p e1009099 (2021)
Electrodermal activity (EDA) is a direct read-out of sweat-induced changes in the skin's electrical conductance. Sympathetically-mediated pulsatile changes in skin sweat measured as EDA resemble an integrate-and-fire process, which yields an inverse
Externí odkaz:
https://doaj.org/article/1129d58290ab40e599ab8e5480b546df
Autor:
Jerry Y. Chao, Rodrigo Gutiérrez, Alan D. Legatt, Elissa G. Yozawitz, Yungtai Lo, David C. Adams, Ellise S. Delphin, Shlomo Shinnar, Patrick L. Purdon
Publikováno v:
Anesthesia and analgesia. 135(6)
Electroencephalogram (EEG) discontinuity can occur at high concentrations of anesthetic drugs, reflecting suppression of electrocortical activity. This EEG pattern has been reported in children and reflects a deep state of anesthesia. Isoelectric eve